On 23 May, Professor Tong Xuemei research group with the Biochemistry and Molecular Cell Biology of College of Basic Medical Sciences of SJTUSM, Research Fellow Li Bin research group with Shanghai Institute on Immunology, and Research Fellow Yang Hui with Huashan Hospital/Institute for Translational Brain Research affiliated to Fudan University jointly publish online in the “Nature Metabolism...

STING (Stimulator of interferon genes) is a vital regulating molecule in the process of natural immunization. The cGAS-STING pathway can sense free DNA and activate the downstream NF-κB and IRF3 signal molecule, and produce Type I interferon, which plays a vital role to the process of infection, autoimmune disease, inflammation response, cell aging, etc. The researches in recent years also sug...