Biography

• Dr. Gao is a professor at the Department of Hypertension of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, the Vice Director of Shanghai Institute of Hypertension, and the Director of Shanghai Key Laboratory of Hypertension. She currently serves as vice chair of the Hypertension Committee of Chinese Geriatric Society, vice chair of the Hypertension Committee of China International Exchange and Promotive Association for Medical and Health Care, standing committee member of China Hypertension League, and member of the Chinese Section of the International Society for Heart Research. She is also an associate editor at Cardiovascular Research and a guest editor at Hypertension.

• Dr. Gao's current research is focused on clinical and basic studies of hypertension. Her main research interests are: (1) etiological screening and treatment strategies of hypertension; (2) the establishment and application of genetic hypertension resources (Dr Gao's team has collected many samples, including hypertensive patients, normotensive subjects, nuclear families and sib-pairs); (3) the mechanisms of vascular remodelling in hypertension, her main focus being the role of inflammatory phenotype of perivascular adipocytes in vascular structure and function; (4) screening and discovery of new biomarkers in vascular injury.

Publications

1. Brown Adipocyte ADRB3 Mediates Cardioprotection via Suppressing Exosomal iNOS. Circ Res. 2022. DOI: 10.1161/CIRCRESAHA.121.320470.

2. PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice. J Exp Med. 2021. DOI: 10.1084/jem.20210252.

3. Perivascular adipose tissue-derived stromal cells contribute to vascular remodeling during aging. Aging Cell. 2019. DOI: 10.1111/acel.12969.

4. A2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling via Promoting Brown Adipose Tissue-Derived FGF21. Cell Metab. 2018. DOI: 10.1016/j.cmet.2018.06.013.

5. Deficiency of Complement C3a and C5a Receptors Prevents Angiotensin II-Induced Hypertension via Regulatory T Cells. Circ Res. 2018. DOI: 10.1161/CIRCRESAHA.117.312153.