CHEN Erzhen
chief physician
Email: chenerzhen@hotmail.com
Tel: 021-
Research Interests: Clinical and basic research of sepsis, severe acute pancreatitis and multiple organ dysfunction syndrome.
Biography
Professor CHEN, a chief physician and doctoral supervisor, is the academic leader in emergency and critical care medicine, as the vice president of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine. He has been working in the front line of emergency and critical care for many years, good at the diagnosis and treatment of severe pancreatitis, sepsis, severe trauma and other critical diseases, as well as major public health emergencies and natural disasters. Engaged in the clinical diagnosis and treatment of emergency and critical diseases for a long time, focusing on the occurrence and development of critical diseases and the mechanism of organ failure, paying attention to the protection of early organ function, going deep into the essence of acute and critical diseases such as severe acute pancreatitis, hemorrhagic shock and sepsis, and attempting to complete clinical translation to put forward new concepts and new technologies oriented by organ function protection.
Publications
Yu X, Wei D, Xu W, Liu C, Guo W, Li X, Tan W, Liu L, Zhang X, Qu J, Yang Z, Chen E. Neutralizing activity of BBIBP-CorV vaccine-elicited sera against Beta, Delta and other SARS-CoV-2 variants of concern. Nat Commun, 2022 Apr 4; 13(1):1788.
Yu X, Wei D, Xu W, Li Y, Li X, Zhang X, Qu J, Yang Z, Chen E. Reduced sensitivity of SARS-CoV-2 Omicron variant to antibody neutralization elicited by booster vaccination. Cell Discov. 2022 Jan 17;8(1):4. doi: 10.1038/s41421-022-00375-5. PMID: 35034952; PMCID: PMC8761745.
Liu T, Dai J, Yang Z, Yu X, Xu Y, Shi X, Wei D, Tang Z, Xu G, Xu W, Liu Y, Shi C, Ni Q, Yang C, Zhang X, 3. 3. Wang X, Chen E, Qu J. Inactivated SARS-CoV-2 vaccine does not influence the profile of prothrombotic antibody nor increase the risk of thrombosis in a prospective Chinese cohort. Sci Bull (Beijing). 2021 Nov 30;66(22):2312-2319. doi: 10.1016/j.scib.2021.07.033. Epub 2021 Jul 27. PMID: 34336365; PMCID: PMC8313791.
Xiao S, Tang C, Zeng Q, Xue Y, Chen Q, Chen E, Han L. Antimicrobial Resistance and Molecular Epidemiology of Escherichia coliFrom Bloodstream Infection in Shanghai, China, 2016-2019. Front Med (Lausanne). 2022 Jan 10;8:803837. doi: 10.3389/fmed.2021.803837. PMID: 35083253; PMCID: PMC8784657.
Zheng YJ, Xie T, Wu L, Liu XY, Zhu L, Chen Y, Mao EQ, Han LZ, Chen EZ, Yang ZT. Epidemiology, species distribution, and outcome of nosocomial Candida spp. bloodstream infection in Shanghai: an 11-year retrospective analysis in a tertiary care hospital. Ann Clin Microbiol Antimicrob. 2021 May 13;20(1):34. doi: 10.1186/s12941-021-00441-y. PMID: 33985505; PMCID: PMC8120712.
Wang YM, Chen Y, Zheng YJ, Huang YC, Chen WW, Ji R, Xu LL, Yang ZT, Sheng HQ, Qu HP, Mao EQ, Chen EZ. Low fluid intake volume during the first 24 h and persistent negative fluid balance from the second day are associated with favorable prognosis for patients with sepsis. Exp Ther Med. 2021 Apr;21(4):387. doi: 10.3892/etm.2021.9818. Epub 2021 Feb 23. PMID: 33680109; PMCID: PMC7918047.
Zhong M, Xu W, Qiu Y, Li L, Qu H, Chen E. Association of Changes in Acute Gastrointestinal Injury Grade with Prognosis in Critically Ill Patients: A Prospective, Single-Center, Observational Study. J Multidiscip Healthc. 2021 Feb 5;14:279-286. doi: 10.2147/JMDH.S291883. PMID: 33574672; PMCID: PMC7872930.
Gong FC, Ji R, Wang YM, Yang ZT, Chen Y, Mao EQ, Chen EZ. Identification of Potential Biomarkers and Immune Features of Sepsis Using Bioinformatics Analysis. Mediators Inflamm. 2020 Oct 9;2020:3432587. doi: 10.1155/2020/3432587. PMID: 33132754; PMCID: PMC7568774.
Huang YZ, Lu GZ, Zhao HS, Liu LJ, Jin J, Wu YF, Wu J, Zhao FL, Liu N, Liu WM, Liu L, Zhu TJ, Chen EZ, Gu Q, Ye HW, Xi XM, Du B, Yi Y, Qiu HB. Clinical features and mortality-related factors of extensive burns among young adults: the Kunshan disaster experience. Ann Transl Med. 2020 Sep;8(17):1053. doi: 10.21037/atm-20-288. PMID: 33145272; PMCID: PMC7575965.
Ji R, Chen Y, Chen W, Wang Y, Gong F, Huang S, Xie R, Zhong M, Liu Z, Yang Z, Fei J, Mao E, Chen E. Identification of Significant Genes and Pathways in Acute Pancreatitis via Bioinformatical Analysis. Dig Dis Sci. 2020 Sep 22. doi: 10.1007/s10620-020-06598-4. Epub ahead of print. PMID: 32960383.
