Tier 2 Professors

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CHEN Fang

Chief Surgeon Doctoral supervisor

Email: chenfang01@sjtu.edu.cn

Tel: 021-

Research Interests:Development of Urogenital Organs, Urinary Reconstruction in Congenital Malformations, Tissue Engineering of Urogenital Organs, Hospital Administration

Biography

  • Chen Fang, Secretary of the Shanghai Sixth People's Hospital Committee of the Communist Party of China. He got his Ph.D from Shanghai Second Medical University in 2004. He is currently a standing Committee Member of Pediatric Surgery Branch of Chinese Medical Association, a supervisor of Shanghai Hospital Association, an editorial board member of Chinese Journal of Pediatric Surgery and Chinese Journal of Hospital Administration.

  • Dr. Chen mainly engaged in the clinic and research in urology, including pathogenesis of congenital urinary malformations, urinary system organ reconstruction, tissue engineering, etc. He ranks at the leading level in the management of complex genitourinary malformations, including hypospadias, bladder exstrophy and epispadias, cloacal malformations, etc.

  • Dr. Chen has led a research team and finished over 15 projects from the National Natural Science Foundation of China, scientific research fund and talent construction projects of the Ministry of National Education and Shanghai Municipal Government. He has 4 licenced patents of invention and utility model, and has published more than 100 papers in Chinese and foreign academic journals.

  • Dr. Chen has won the Special Government Allowance of the State Council, the Shanghai Medical Leading Talent Plan, the title of Shanghai Excellent Discipline Leader, the Science and Technology Innovation Award of the Chinese Hospital Association, the Song Ching Ling Pediatric Medicine Award, the Science and Technology Progress Award of the State Education Commission and the Ministry of Health, the Shanghai Science and Technology Progress Award, the Strongest Leadership Prize for Chinese hospital administrators(13th),etc.

Publications(recent 5 years)

  1. Lyu YQ, Yu L, Xie H, Huang YC, Li XX, Sun L, Liang Y, Chen F*. Spongiosum-combined glanuloplasty reduces glans complications after proximal hypospadias repair. Asian J Androl. 2021 Sep-Oct;23(5):532-536.

  2. Chen Z, Xie H, Chen F*. Re: Vuthy Ea, Anne Bergougnoux, Pascal Philibert, et al. How Far Should We Explore Hypospadias? Next-generation Sequencing Applied to a Large Cohort of Hypospadiac Patients. Eur Urol 2021;79:507-515. Eur Urol. 2021 Jul;80(1):e10-e11.

  3. CAI Qin-yi,LIU Yi-cheng,LUO Li ,TAO Min-fang, CHEN Fang*.Exploration of the Construction of Emergency Medical Rescue Reserve Service Corps of Prevention and Control of Major Epidemics in Health Institutions[J].Chinese Hospital Management,2021,41(6):5-7.

  4. 蔡沁怡,刘义成,罗莉,陶敏芳,陈方*.医疗机构重大疫情防控应急医疗救治预备役队伍建设探讨[J]. 中国医院管理,2021,41(6):5-7.

  5. Yu M, Bian Y, Wang L, Chen F*. Low-intensity pulsed ultrasound enhances angiogenesis in rabbit capsule tissue that acts as a novel vascular bed in vivo. Adv Clin Exp Med. 2021 Jun;30(6):581-589.

  6. Peng X, Guo H, Yuan J, Chen Y, Xia Y, Wang L, Wang Y, Huang Y, Xie H, Wang Y*, Chen F*. Extracellular vesicles released from hiPSC-derived MSCs attenuate chronic prostatitis/chronic pelvic pain syndrome in rats by immunoregulation. Stem Cell Res Ther. 2021 Mar 20;12(1):198. doi: 10.1186/s13287-021-02269-x. PMID: 33743834; PMCID: PMC7981875.

  7. Wang L, Yu M, Peng X, Wang Y, Chen F*. Assessing the potential regeneration ability of corpus spongiosum in rabbit models. Andrologia. 2021 Feb;53(1):e13901.

  8. Guo HL, Peng XF, Bao XQ, Wang L, Jia ZM, Huang YC, Zhou JM, Xie H, Chen F*. Bladder reconstruction using autologous smooth muscle cell sheets grafted on a pre-vascularized capsule. Theranostics. 2020 Aug 20;10(23):10378-10393.

  9. Guo HL, Wang L, Jia ZM, Bao XQ, Huang YC, Zhou JM, Xie H, Yang XJ, Chen F*. Tissue expander capsule as an induced vascular bed to prefabricate an axial vascularized buccal mucosa-lined flap for tubularized posterior urethral reconstruction: preliminary results in an animal model. Asian J Androl. 2020 Sep-Oct;22(5):459-464.

  10. Chen Z, Lin X, Wang Y, Xie H, Chen F*. Dysregulated expression of androgen metabolism genes and genetic analysis in hypospadias. Mol Genet Genomic Med. 2020 Aug;8(8):e1346. doi: 10.1002/mgg3.1346. Epub 2020 Jun 8. PMID: 32515122; PMCID: PMC7434757.

  11. LIU Yi-cheng,CHEN Fang*,DUO Qi.Exploration and practice of strengthening political construction of Communist Party in public hospitals[J].Chinese Health Resources,2019,22(5):382-385.

  12. 刘义成,陈方*,多琦.加强公立医院党的政治建设的探索和实践[J].中国卫生资源,2019,22(5):382-385.

  13. Chen Z, Lin X, Lei Y, Chen H, Finnell RH, Wang Y, Xu J, Lu D*, Xie H*, Chen F*. Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13. BMC Med Genomics. 2019 Dec 19;12(1):196.

  14. Bao Xingqi,Huang Yichen,Xie Hua,Lyu Yiqing,Yu Ling,Li Zhi,Fu Qiang,Song Lujie,Chen Fang*.A histomorphological study of corpus spongiosum around urethral plate in hypospadias[J].Chin J Peditar Surg,2019,40(11):1030-1035.

  15. 鲍星奇,黄轶晨,谢华,吕逸清,余玲,奚政君,李治,傅强,宋鲁杰,陈方*.尿道下裂尿道板周围尿道海绵体的组织形态学研究[J].中华小儿外科杂志,2019,40(11):1030-1035.

  16. Jia Z, Guo H, Xie H, Zhou J, Wang Y, Bao X, Huang Y, Chen F*. Construction of Pedicled Smooth Muscle Tissues by Combining the Capsule Tissue and Cell Sheet Engineering. Cell Transplant. 2019 Mar;28(3):328-342.

  17. Bao XQ, Huang YC*, Chen F*. C-Phycocyanin Alleviates Bladder Inflammation and Dysfunction in Cyclophosphamide-Induced Cystitis in a Mouse Model by Inhibiting COX-2 and EP4. Evid Based Complement Alternat Med. 2019 Jul 29;2019:8424872.

  18. Guo HL, Jia ZM, Wang L, Bao XQ, Huang YC, Zhou JM, Xie H, Yang XJ, Chen F*. Tubularized urethral reconstruction using a prevascularized capsular tissue prelaminated with buccal mucosa graft in a rabbit model. Asian J Androl. 2019 Jul-Aug;21(4):381-386.

  19. Lyu Y, Yu L, Xie H, Huang Y, Li X, Sun L, Bao J, Liang Y, Zhou X, Chen F*. Comparison of short-term complications between Onlay and Duckett urethroplasty and the analysis of risk factors. Int Urol Nephrol. 2019 May;51(5):783-788.

  20. LI Bin, WANG Lijun, CAO Houde , ZHENG Yunxing, JIANG Ruiyao, QIAN Jianguo, CAO Shaoping, ZHANG Lifang, GE Yi, BI Fan, CAO Hui, CHEN Fang*.Improvement of Medical Device “Made in China” Based on Ten-Year Data of the Shanghai Medical Device Market Survey[J].Chinese Medical Equipment,2018,33(2):23-26.

  21. 李斌,汪黎君,曹厚德,郑蕴欣,姜瑞瑶,钱建国,曹少平,张力方,葛毅,毕帆,曹辉,陈方*.基于上海市场十年调查数据看医疗设备"中国制造"的提升[J].中国医疗设备,2018,33(2):23-26.

  22. Wang L, Yang G, Xie H, Chen F*. Prospects for the research and application of biodegradable ureteral stents: from bench to bedside. J Biomater Sci Polym Ed. 2018 Oct;29(14):1657-1666.

  23. Wu M, Chen F*, Xie H, Lv Y, Huang Y, Liu Y, Ye W. Management of failed hypospadias: choosing the right method and achieving optimal results. Int Urol Nephrol. 2018 Oct;50(10):1795-1800.

  24. Xie H, Lin XL, Zhang S, Yu L, Li XX, Huang YC, Lyu YQ, Chen HT, Xu J*, Chen F*. Association between diacylglycerol kinase kappa variants and hypospadias susceptibility in a Han Chinese population. Asian J Androl. 2018 Jan-Feb;20(1):85-89.

  25. Wei R, Zhang R, Li H, Li H, Zhang S, Xie Y, Shen L*, Chen F*. MiR-29 Targets PUMA to Suppress Oxygen and Glucose Deprivation/Reperfusion (OGD/R)-induced Cell Death in Hippocampal Neurons. Curr Neurovasc Res. 2018;15(1):47-54. doi: 10.2174/1567202615666180403170902. PMID: 29623838.

  26. Huang Yichen,Chen Fang*.How should we manage the exstrophy-epispadias complex nowadays?[J].Chin J Pediatr Surg,2018,39(7):481-483.

  27. 黄轶晨,陈方*.当下我们应该怎么处理膀胱外翻?[J].中华小儿外科杂志,2018,39(7):481-483.

  28. Chen Fang*,Zhang Weiping.Developments and researches of pediatric urological surgery from the per-spectives of evolving treatments for hypospadias[J]. J Clin Ped Sur,2018,17(8):564-566.

  29. 陈方*,张潍平.从尿道下裂手术变迁谈小儿泌尿外科临床研究的必要性[J]. 临床小儿外科杂志,2018,17(8):564-566.

  30. Huang Yichen,Chen Fang*,Xie Hua,Lyu Yiqing,Yu Ling,Li Xiaoxi,Chen Yan,Yang Ganggang,Sun Huizhen,Liang Yan.Modified Cantwell-Ransley repair via a ventral penile approach for preserving the integrity of corpus spongiosum for male epispadias[J].Chin J Pediatr Surg,,2018,39(2):131-136.黄轶晨,陈方*,谢华,吕逸清,余玲,李晓溪,陈艳,杨刚刚,孙会振,梁龑.阴茎腹侧入路保留完整尿道海绵体的改良Cantwell-Ransley术治疗尿道上裂[J]. 中华小儿外科杂志,2018,39(2):131-136.

  31. Jia Zhiming,Guo Hailin,Chen Fang*.Research Progress of Vascularization Within Engineered Tissues[J].Journal of Tissue Engineering and Reconstructive Surgery,2018,14(1):39-42.

  32. 贾智明,郭海林,陈方*. 组织工程组织血管化的研究进展[J]. 组织工程与重建外科杂志,2018,14(1):39-42.

  33. Yu Ling,Lv Yiqing,Huang Yichen,Li Xiaoxi,Sun Li,Chen Yan,Bao Jiewen,Sun Huizhen,Xu Zhanyuan,Yang Ganggang,Chen Fang*,Xie Hua.Sim-ple suture ligation technique for repairing small urethrocuta-neous fistulae (≤3 mm) after hypospadias surgery[J]. J Clin Ped Sur,2018,17(8):585 -588.

  34. 余玲,吕逸清,黄轶晨,李晓溪,孙莉,陈艳,包杰文,孙会振,徐展远,杨刚刚,陈方*,谢华.单环缝扎法治疗小儿尿道下裂术后3 mm以下尿道皮肤瘘的临床研究[J].临床小儿外科杂志,2018,17(8):585-588.