Biography

• Professor Zhang Jianjun, chief physician, doctoral supervisor；Director of Liver Surgery, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.

• He is the member and secretary general of Transplant Immunology Branch of Chinese Society of Immunology, member and secretary general of Pediatric Transplantation Professional Committee of Organ Transplant Physicians Branch of Chinese Medical Doctor Association, and member and secretary general of Organ Transplant Branch of Shanghai Medical Association. Over the past 20 years, he performed thousands of various hepatectomy, and liver transplantation, including more than 2000 cases of infant living donor liver transplantation. He specializes in the diagnosis and surgical treatment of liver cirrhosis, liver cancer and other hepatobiliary system diseases caused by various causes, especially in living donor liver transplantation for children and adults.

• His research interests include the pathogenesis of liver cancer, perioperative treatment of liver transplantation, mechanism of organ ischemia-reperfusion injury and acute liver injury, and organ preservation. As the editorial board member of many core journals, such as Transplantation Journal and Chinese Digestive Surgery, he has published more than 90 papers. He also won the second prize of National Science and Technology Progress, the first prize of Shanghai Science and Technology Progress, the first prize of higher Education Science and Technology Progress, the first prize of Huaxia Medical Science Award and the first prize of Shanghai Medical Science and Technology Award, due to his contributions to pediatric liver transplantation.

Publications

1. Zhang Jian Jun; Han, Conghui; Dai, Huijuan; Hou, Jianquan; Dong, Yang; Zhang, Jianjun Cui, Xiaolan; Xu, Longmei; Zhang, Ming; Xia, Qiang，Hypoxia-Inducible Factor-2alpha Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury.，J Am Soc Nephrol，2016.1.01，27（1）：92~106

2. Zhou Tao, Chang Ling, Luo Y, Zhou Y, Zhang JJ. Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy. Redox Biology.2019 Feb;21:101120.

3. Zhang, Jianjian; Zhang, Ming; Zhang, Jianjun; Xia, Qiang，A Novel Mouse Model of Liver Ischemic/Reperfusion Injury and its Differences to the Existing Model.，J Invest Surg，2015.01.01，28（5）：283~291

4. Chen, Xiaosong; Zhang, Jianjian; Han, Conghui; Dai, Huijuan; Kong, Xianming; Xu, Longmei; Xia, Qiang; Zhang, Ming; A sexual dimorphism influences bicyclol-induced hepatic heat shock factor 1 activation and hepatoprotection.，Mol Pharmacol，2015.7.01，88（1）：38~47

5. Zhuang S, Hua X, He K, Zhou T, Zhang J, Wu H, Ma X, Xia Q, Zhang J.Inhibition of GSK-3β induces AP-1-mediated osteopontin expression to promote cholestatic liver fibrosis. FASEB J. 2018 Aug;32(8):4494-4503.

6. He K, Xia L, Zhang J.LPS ameliorates renal ischemia/reperfusion injury via Hsp27 up-regulation.Int Urol Nephrol. 2018 Mar;50(3):571-580.

7. He, Kang; Chen, Xiaosong; Han, Conghui; Xu, Longmei;  Zhang, Jianjun ;Zhang, Ming; Xia, Qiang，Lipopolysaccharide-induced cross-tolerance against renal ischemia-reperfusion injury is mediated by hypoxia-inducible factor-2alpha-regulated nitric oxide production.，Kidney Int，2014.2.01，85（2）：276~288

8. Hua X, Lu T, Zhang J, Miao Q, Bian Z, Zhang H, Huang S, Lin W, Xi Z, Zhang M, Chen Q, Ma X, Zhang J, Xia Q. Hypoxia-Inducible Factor-2alpha Promotes Hepatocyte Apoptosis during Cholestasis. Hepatol Res. 2017 Jan;47(1):95-102. 共同通讯

9. Zhang, Shun; Han, Cong-Hui; Chen, Xiao-Song; Zhang, Ming; Xu, Long-Mei; Xia, Qiang，Zhang, Jian-Jun. Transient ureteral obstruction prevents against kidney ischemia/reperfusion injury via hypoxia-inducible factor (HIF)-2alpha activation.，PLoS One，2012.01.01，7（1）：e29876~e29876

10. Xu N, Shen C, Luo Y, Xia L, Xue F, Xia Q, Zhang J.Upregulated miR-130a increases drug resistance by regulating RUNX3 and Wnt signaling in cisplatin-treated HCC cell. Biochem Biophys Res Commun. 2012.24;425(2):468-72

11. Xue F, Han LZ, Chen YK, Xi ZF, Li QG, Xu N, Xia Y, Streicher K, Zhang JJ, Xia Q. CYP3A5 genotypes affect tacrolimus pharmacokinetics and infectious complications in Chinese pediatric liver transplant patients. Pediatric Transplantation,2014,18（2）: 166-176

12. HUIJUAN DAI, DAN CUI, DAWEI LI, BO ZHAI, JIANJIAN ZHANG and JIANJUN ZHANG. Hepatic abscess with hepatobronchial fistula following percutaneous radiofrequency ablation for hepatocellular carcinoma: A case report. ONCOLOGY LETTERS 9: 2289-2292, 2015

13. Junda Gao#, Kang He#*, Qiang Xia, Jianjun Zhang. Research progress on hepatic machine perfusion. Int J Med Sci 2021 Mar 3;18(9):1953-1959

14. Zi-yun Qiao, Zi-jie Zhang, Zi-cheng Lv, Huan Tong, Zhi-feng Xi, Hao-xiang Wu, Xiao-song Chen, Lei Xia, Hao Feng, Jian-jun Zhang and Qiang Xia. Neoadjuvant Programmed Cell Death 1 (PD-1) Inhibitor Treatment in Patients With Hepatocellular Carcinoma Before Liver Transplant: A Cohort Study and Literature Review. Front Immunol. 2021 Jul 19;12:653437.