LU Peihua
LU Peihua
Professor
Research area: Immunization and treatment of spinal cord injury. (2000-2010) Immunization and recurrent spontaneous abortion. (1990-2010) Cellular immunity and human leukocyte antigen (HLA). (1978-1999)
Email: peihualua3@aliyun.com
Tel: 021-64731908
Education
M.S. June 1989, Department of Immunology, Shanghai Second Medical University, Shanghai, China
M.D. December 1976, Department of Pediatrics, Shanghai Second Medical University, Shanghai, China
Professional Experience
Jun 2009 - Retired,8 years as teaching supervisor in Shanghai Jiao Tong University School of Medicine
Jan 2000 - Jun 2009 Professor, Chief, Department of Neurobiology, Shanghai Jiao Tong University School of Medicine
Oct 1978 - Dec 1999 Assistant Professor, Associate Professor, Professor, Shanghai Institute of Immunology, Shanghai Second Medical University
Jul 1991 - Dec 1991 Visiting Scholar, Molecular Genetics Laboratory, United Kingdom Transplant Support Service, Bristol, UK
Jul 1987 - Dec 1987 Visiting Scholar, Department of Transplantation Immunology, Kitasato University School of Medicine, Kitasato, Sagamihara, Kanagawa, Japan
Honors
Second Prize of National Science and Technology Progress Award, Project "Diagnose, Treatment and Mechanisms of Recurrent Immunity Spontaneous Abortion ", awarded by the People's Republic of China State Council, 2008
Second Prize of National Natural Science Award, Project "Treatment and Mechanisms of Recurrent Spontaneous Abortion ", awarded by the People's Republic of China State Council, 2003
Award Nomination of Excellent Teacher, awarded by Shanghai Committee of Education, 2000
Excellent Professor, awarded by Shanghai Second Medical University, 2000
Shanghai Outstanding Woman, awarded by Shanghai federation of trade unions, 1997
First Prize of Bang Sheng, awarded by “Bang Shang” Foundation, 1996
Special Government Allowances, awarded by the People's Republic of China State Council, Since 1992
Second Prize of National Science and Technology Progress Award, Project "Studies on Chinese HLA-Dw", awarded by the People's Republic of China State Council, 1991
First Prize of Shanghai Science and Technology Progress Award, Project "Studies on Chinese HLA-Dw", awarded by Shanghai Municipal People's Government, 1990
Publications
Jing-Ya Huang, Yan-Xia Wang, Wen-Li Gu, Sai-Li Fu, Ying Li, Li-Dong Huang, Zhen Zhao, Qin Hang, Hui-Qin Zhu and Pei-hua Lu: Expression and Function of Myelin-associated Proteins and Their Common Receptor NgR on Oligodendrocyte Progenitor Cells. Brain Research 1437:1-15, 2012
Chao-Jin Xu, Liang Xu, Li-Dong Huang, Ying Li, Pan-Pan Yu, Qin Hang Xiao-Ming Xu, Pei-hua Lu: Combination Therapy with NgR Vaccine and Neural Stem Cells Promotes Functional Recovery after Spinal Cord Injury in Adult Rats. Neuropathology and Applied Neurobiology 37(2):135-55, 2011
He-Zuo Lü, Yan-Xia Wang, Jian Zou, Ying Li, Sai-Li Fu, Jian-Qiang Jin,Jian-Guo Hu and Pei-hua Lu:Differentiation of Neural Precursor Cell-derived Oligodendrocyte Progenitor Cells Following Transplantation into Normal and Injured Spinal Cords. Differentiation 80 (2010)228-240, 2010
Liang Xu, Chao-jin Xu, He-Zuo Lü, Yan-Xia Wang, Ying Li and Pei-hua Lu: Long-term Fate of Allogeneic Neural Stem Cells Following Transplantation into Injured Spinal Cord. Stem Cell Reviews and Reports 6(1):121-136 2010
Zhifang Chen, Zhengwen Ma, Yanxia Wang, Ying Li, Hezuo Lü, Saili Fu, Qin Hang, Pei-hua Lu : Oligodendrocyte–Spinal Cord Explant Co-culture: an In Vitro Model for the Study of Myelination. Brain Research, 1309: 9-18, 2010 (with cover)
Wenli Gu, Saili Fu, Yanxia Wang, Ying Li, Hezuo Lü, Xiaoming Xu and Peihua Lu: Chondroitin Sulfate Proteoglycans Regulate the Growth, Differentiation and Migration of Multipotent Neural Precursor Cells through the Integrin Signaling Pathway. BMC Neuroscience, 10:128, 2009
Panpan Yu, Lidong Huang, Jian Zou, Zhihua Yu, Yanxia Wang, Xiaofei Wang, Liang Xu, Xinqiu Liu, Xiao-Ming Xu, and Pei-hua Lu: Immunization with recombinant Nogo-66 receptor (NgR) promotes axonal regeneration and recovery after spinal cord injury in rats. Neurobiology of Disease, 32:535-542, 2008
He-Zuo Lü, Liang Xu, Jian Zou, Yan-Xia Wang, Zheng-Wen Ma, Xiao-Ming Xu, and Pei-hua Lu: Effects of autoimmunity on recovery of function in adult rats following spinal cord injury. Brain, Behavior, and Immunity, 22 (8): 1217-1230, 2008
He-Zuo Lü, Yan-Xia Wang, Ying Li, Sai-Li Fu, Qin Hang, Pei-hua Lu: Proliferation and differentiation of oligodendrocyte progenitor cells induced from rat embryonic neural precursor cells followed by flow cytometry. Cytometry A 73 (8): 754-60, 2008
Bao-Ming Nie, Xiao-Yan Jiang, Jin-Xian Cai, Sai-Li Fu, Li-Min Yang, Lin Lin, Qin Hang, Pei-hua Lu: and Yang Lu: Panaxydol and panaxynol protect cultured cortical neurons against Abeta25-35-induced toxicity. Neuropharmacology. 54 (5): 845-53, 2008
Lan Yin, Sai-Li Fu, Gui-Ying Shi, Ying Li, Jian-Qiang Jin, Zheng-Wen Ma and Pei-hua Lu: Expression and regulation of MHC on neural stem cells and their lineages. Stem Cell and Development, 17: 53-65, 2008
Sai-Li Fu, Jian-Guo Hu, Ying Li, Yan-Xia Wang, Jian-Qiang Jin, Xiao-Ming Xu, Pei-hua Lu : A simplified method for generating oligodendrocyte progenitor cells from neural precursor cells isolated from the embryonic rat spinal cord. Acta Neurobiologiae Experimentalis 67 (4): 367-377, 2007
Xiaofei Wang, Saili Fu, Yanxia Wang, Panpan Yu, Jianguo Hu, Wenli Gu, Xiao-Ming Xu, Peihua Lu: Interleukin-1β mediates proliferation and differentiation of multipotent neural precursor cells through the activation of SAPK/JNK pathway. 36: Molecular and Cellular Neuroscience 343-354, 2007 (with cover)
Wen-Li Gu, Sai-Li Fu, Yan-Xia Wang, Ying Li, Xiao-Fei Wang, Xiao-Ming Xu and Pei-hua Lu: Expression and Regulation of Versican in Neural Precursor Cells and Their Lineages. Acta Pharmacologica Sinica 28 (10): 1519-30, 2007 (with cover)
Panpan Yu, Lidong Huang, Jian Zou, Huiqing Zhu, Xiaofei Wang, Zhihua Yu, Xiaoming Xu and Peihua Lu: DNA Vaccine against NgR Promotes Functional Recovery after Spinal Cord Injury in Adult Rats. Brain Research 25(1147):66-76, 2007
Xiao-Fei Wang, Lan Yin, Jian-Guo Hu , Li-Dong Huang, Pan-Pan Yu, Xiao-Yan Jiang, Xiao-Ming Xu, Pei-hua Lu:Expression and localization of p80 interleukin-1 receptor protein in the rat spinal cord. Journal of Molecular Neuroscience 29:45-54, 2006
Xiao-Fei Wang, Li-Dong Huang, Pan-Pan Yu, Jian-Guo Hu, Lan Yin, Li Wang, Xiao-Ming Xu, Pei-hua Lu: Upregulation of type I interleukin-1 receptor after traumatic spinal cord injury in adult rats. Acta Neuropathologica 111:220-228,2006
S.-L. FU, Z.-W. MA, L. YIN, C. IANNOTTI, P.-H LU and X.-M. XU: Region-Specific Growth Properties and Trophic Requirements of Brain- and Sinal Cord-Derived Embryonic Neural Presursor Cells. Neuroscience 135(3):851-62, 2005
Wang X, Lin Q, Ma Z, Hong Y, Zhao A, Di W, Lu P: Association of the A/G Polymorphism at Position 49 in Exon 1 of CTLA-4 with the Susceptibility to Unexplained Recurrent Spontaneous Abortion in the Chinese Population. American Journal of Reproductive Immunology 53: 100–105, 2005
FU Sai-Li, HU Jian-Guo, LI Ying, YIN Lan, JIN Jian-Qiang, XU Xiao-Ming, Lu Pei-Hua:Induction of rat neural stem cells into oligodendrocyte precursor cells. ACTA Physiologica Sinica 57(2):132-138,2005
Wang Yan-Ting, Han Shu, Zhang Kai-Hua, Xu Xiao-Ming, Lu Pei-Hua: Upregulation of Heprin-Binding Growth Associated Molecules After Spinal Cord Injury in Adult Rats. Acta Pharmacologica Sinica. 25 (5):611-616, 2004
Huang Lidong, Lin Lin, Ma Zhengwen, Fu Saili, Zhou guangyen, Fan Lian, Wang Yuan, Chen Shunle, Lu Pei-Hua:Studies on HLA-DRB1, DQA1, DQB1 Haplotypes of SLE Patients with Autologous Anti-phospholipid Antibodies. U.S.Chinese J of Microbiology and Immunology 2(1):73,2000
J.L.Bidwell , P.Lu , Y.Wang , K.Zhou , T.M.Clay , R.E. Bontrop: DQB,DQA,DQB and DPB Nucleotide Sequences of Sanguinus Oedipus B95-8 . European Journal of Immunogenetics 21:67,1994
Lu Pei-Hua, Zhou Guang-Yan, Chen Guang-Xun, Fu Sai-Li, Yu Qiang, Chen Jing-Hai, XuWen Yu and Zang Ren-Jie: Screening and Identification of HLA Homozygous Cells in Chinese Population. Chinese Journal of Genetics (Acta Genetica Sinica) 15(3):323, 1988
Book Chapters
《Cellular and Molecular Biology of Synaptic Transmission in Neurons》Zu-Hang Shang (Editor-in-Chief), Pei-hua Lu (Associate Editor), Shanghai Science and Technology Publishing House, 2008
《Principle of Immunology》Guang-Yan Zhou (Editor-in-Chief), Pei-hua Lu (Chapter 11, Immune Regulation, p.191-206), Shanghai Science and Technology Publishing House, 2000
《Modern Medical Immunology》Chuan-Lin Yu et al.(Editor-in-Chief), Pei-hua Lu (Chapter 78, Transplantation Immunology, p.996-1013), Shanghai Medical University Press, 1998