CHENG Weiwei
Professor (Chief physician)
Research area: Pathological pregnancy; Prenatal diagnosis
Email: wwcheng29@shsmu.edu.cn
Tel: 021-64070434
Biography
Cheng Weiwei, MD, PhD, Professor, chief obstetrician and gynaecologist. The president of the International Peace Maternal and Child Health Hospital Affiliated to Shanghai Jiaotong University, Chair of Shanghai birth defect prevention center, Chair of Prenatal and diagnosis quality Center, etc.
Professor Cheng has presided over and undertaken nearly 30 national or Shanghai multi center research projects and basic research projects. Won the third prize of Shanghai Science and Technology Progress Award, the National Maternal and Child Health Award, the Huaxia Medical Award, The National May 1st Labour Medals Award, Benevolent doctor Award, State Council special allowance Award.
Professor Cheng’s main research fields are: 1) pathogenesis of preeclampsia or other high risk pregnancy; 2) Prenatal diagnosis: early diagnosis and pathogenesis of congenital heart disease or other rare disease of fetus. As the first author or Corresponding author, more than 70 papers have been published, including nearly 40 SCI papers. Trained more than 10 phD students and 20 MD students.
Publications ( corressponding author)
Jinyu, L., Shuying, W., Panchan, Z., Dan, C., Chao, C., Xingyu, Y., & Weiwei, C. (2022). Bone marrow stromal cell antigen 2 (BST2) suppresses the migration and invasion of trophoblasts in preeclampsia by downregulating matrix metallopeptidase 2 (MMP2). Bioengineered, 13(5), 13174-13187.
Ye, B., Wu, Y., Chen, J., Yang, Y., Niu, J., Wang, H., ... & Cheng, W. (2021). The diagnostic value of the early extended fetal heart examination at 13 to 14 weeks gestational age in a high-risk population. Translational Pediatrics, 10(11), 2907.
Chen, D., He, B., Zheng, P., Wang, S., Zhao, X., Liu, J., ... & Cheng, W. (2021). Identification of mRNA-, circRNA-and lncRNA-associated ceRNA networks and potential biomarkers for preeclampsia from umbilical vein endothelial cells. Frontiers in molecular biosciences, 8, 652250.
Chen, C., Gao, J., Chen, D., Liu, J., He, B., Chen, Y., ... & Cheng, W. (2022). miR-4443/MMP2 suppresses the migration and invasion of trophoblasts through the HB-EGF/EGFR pathway in preeclampsia. Cell Cycle, 1-16.
Xu, X., Ye, B., Li, M., Xia, Y., Wu, Y., & Cheng, W. (2022). The UA Doppler Index, Plasma HCY, and Cys C in Pregnancies Complicated by Congenital Heart Disease of the Fetus. Journal of Clinical Medicine, 11(19), 5962.
Lang, X., Zhao, W., Huang, D., Liu, W., Shen, H., Xu, L., ... & Cheng, W. (2019). The role of NUDT21 in microRNA‐binding sites of EZH2 gene increases the risk of preeclampsia. Journal of Cellular and Molecular Medicine, 23(5), 3202-3213.
He, B., Yang, X., Li, Y., Huang, D., Xu, X., Yang, W., ... & Cheng, W. (2018). TLR9 (toll-like receptor 9) agonist suppresses angiogenesis by differentially regulating VEGFA (vascular endothelial growth factor a) and sFLT1 (soluble vascular endothelial growth factor receptor 1) in preeclampsia. Hypertension, 71(4), 671-680.
Hu, X., Ao, J., Li, X., Zhang, H., Wu, J., & Cheng, W. (2018). Competing endogenous RNA expression profiling in pre-eclampsia identifies hsa_circ_0036877 as a potential novel blood biomarker for early pre-eclampsia. Clinical epigenetics, 10(1), 1-12.
Ouyang, F., Tang, N., Zhang, H. J., Wang, X., Zhao, S., Wang, W., ... & Cheng, W. (2018). Maternal urinary triclosan level, gestational diabetes mellitus and birth weight in Chinese women. Science of The Total Environment, 626, 451-457.
Wang, Y., Chen, Y., Tian, F., Zhang, J., Song, Z., Wu, Y., ... & Cheng, W. (2014). Maternal mosaicism is a significant contributor to discordant sex chromosomal aneuploidies associated with noninvasive prenatal testing. Clinical chemistry, 60(1), 251-259.
