Research Interests

1. Investigating the molecular mechanism underlying tumorigenesis and progression of gallbladder cancer.

2. 2.Screening and identification of biomarkers for early diagnosis, monitoring therapeutic efficacy and prognosis judgment of gallbladder cancer.

3. Study on the efficacy of novel small-molecule targeted drugs (including small-molecule drugs and their drug-loaded materials) combined with chemotherapeutic agents for gallbladder cancer.

4. Study on tumor microenvironment and immunotherapy of gallbladder cancer.

5. Study on PDX models and organoids of gallbladder cancer.

6. Revealing the spatial structure of gallbladder cancer by spatial transcriptome sequencing and single-cell transcriptome sequencing.