Research Interests

• -Nanobiology and Tumor Therapy

• Biological effects of nanomaterials (e.g. interaction between inorganic nanomaterials and proteins; autophagy induced by nanomaterials) and their application in tumor therapy, including: the discovery of specific interactions between carbon nanomaterials and cellular signaling proteins CaMKII, the clarification of  the new mechanism of CaMKII activation; the proposal of a new strategy for osteosarcoma therapy through nanomaterials induced autophagy downstream regulation.

• -Microenvironment Regulation and Intervention Strategies of Bone Tumor.

• The application of novel Nanoparticle Drug Delivery System in the diagnosis and treatment of osteosarcoma by regulating tumor acidic / metabolic / immune microenvironment.