Ottawa-Shanghai Joint School of Medicine


LU Haixia

Associate Professor


Tel: 86-21-53316065

Research Interests

  • prevention and management of early children caries, periodontal disease and general health, oral epidemiology and oral biostatistics


  • Dr. Haixia Lu, the director of Discipline and Research office, Shanghai Jiao Tong University, College of Stomotology, office director of National Clinical Research center for Oral Diseases, and deputy office director of the National Center of Stomatology, Ninth People's Hospital. Member of the Dental Prevention Committee of the Chinese Stomatological Association, Member of the Dental Prevention Committee of the Chinese Preventive Medicine Association. She attained PhD degree from Dental Public Health, Faculty of Dentistry, The University of Hong Kong in 2011, and visited the University of Washington in 2009 as a visit scholar. She has long been engaged in the professional medical education and research of Preventive Dentistry. Her research interests include prevention and management of early children caries, periodontal disease and general health, oral epidemiology and oral biostatistics. As the principal investigator, she was awarded one National Natural Science Foundation of China and three provincial and ministerial projects. She also published more than 50 journal papers, including 19 SCI papers as the first or corresponding authors, particularly in the Journal of Dental Research, Community Dentistry and Oral epidemiology. She is the editorial board member of the International Dental Journal, the official journal of the World Dental Federation FDI, and the young editorial board member of the Shanghai Journal of Preventive Medicine. She is also a reviewer for Journal of Dental Research, Community Dentistry and Oral Epidemiology, and BMC oral health. As the main drafter, she drafted the national health industry standard "Oral Health Survey and Examination Methods". As the main writer, she compiled the clinical guidelines for the Diagnosis and Prevention of Dentin Sensitivity (Revised 2019). She was awarded the third prize of the Heraeus Gosa Medical Education Award in 2014 and 2015. In 2015, it was funded by the Excellent Youth Project of the Ninth People's Hospital. Member of high-level local university innovation team in Shanghai Jiaotong University School of Medicine. The 2017 National Conference on Oral Preventive Medicine won the second prize for outstanding papers.


  1. Lu HX, Wong MCM, Lo ECM, McGrath C. Trends in oral health from childhood to early adulthood: a life course approach. Community Dent Oral Epidemiol. 2011; 39(4): 352-60.

  2. Lu HX, Wong MCM, Lo ECM, McGrath C. Risk indicators of oral health status among young adults aged 18 years analyzed by negative binomial regression. BMC oral health. 2013,13:40.

  3. Lu HX,Tang C,Chen X,Wong MCM,Ye W. Characteristics of patients complaining of halitosis and factors associated with halitosis. Oral Disease. 2014; 20: 787-795.

  4. Lu HX, Wong MCM, Lo ECM, McGrath C. Oral health related quality of life among young adults. Applied Research in Quality of Life. 2015 10(1): 37-47.

  5. Lu HX, Xu W, Wong MCM, Wei TY, Feng XP. Impact of periodontal conditions on the quality of life of pregnant women: A cross-sectional study. Health and Quality of Life Outcomes. 2015, 13:67.

  6. Zhu C, Li F, Wong MCM, Feng XP, Lu HX*, Xu W. Association between Herpesviruses and Chronic Periodontitis: A Meta-Analysis Based on Case-Control Studies. PLoS ONE. 2015 Dec 14; 10(12): e0144319. doi: 10.1371/journal.pone.0144319.

  7. Lu HX, Zhu C, Li F, Xu W, Tao DY, Feng XP. Putative periodontopathic bacteria and herpesviruses in pregnant women: a case-control study. Scientific Reports. 2016, 6: 27796. IF:4.9; JCR分区Q1

  8. Lu HX, Chen XL, Wong MCM, Zhu C, Ye W. Oral health impact of halitosis in Chinese adult. Int J Dent Hyg. 15, 2017, e85-e92.

  9. Li F, Tao D, Feng X, Wong MCM and Lu H. Establishment and Development of Oral Microflora in 12–24 Month-Old Toddlers Monitored by High-Throughput Sequencing. Front. Cell. Infect. Microbiol/ Frontiers in Cellular and Infection Microbiology. 2018; 8: 422. doi: 10.3389/fcimb.2018.00422.

  10. Tao D, Li F, Feng X, Wong MCM, Lu H. Plaque biofilm microbial diversity in infants aged 12 months and their mothers with or without dental caries: a pilot study. BMC Oral Health. 2018 Dec 29;18: 228. doi: 10.1186/s12903-018-0699-8.

  11. Qi Lei, Qian Yifeng, Zhu Fangxing, Cao Ningning, Lu Haixia*, Zhang Lei. Association between periodontal disease and tooth loss and mortality in an elderly Chinese population. Aging Clinical and Experimental Research (Aging Clin Exp Res). 2020 Feb 4. doi: 10.1007/s40520-019-01446-6.

  12. Yifeng Qian, Weijun Yuan, Nianrou Mei, Jiaqing Wu, Qingyu Xu, Haixia Lu, Xudong Wang, Periodontitis increases the risk of respiratory disease mortality in older patients, Experimental Gerontology (Exp Gerontol), 13. 2020, 133, 110878.

  13. *共同通讯作者

  14. He Mei#, Lu Hai-Xia#, Cao Jun-Yao, Zhang Yu, Wong MCM, Fan Juan, Ye Wei. Psychological characteristics of Chinese patients with genuine halitosis. Oral Dis. 2020 Oct; 26(7):1576-1585.

  15. # 共同第一作者

  16. Dan-Ying Tao#, Jia-Lin Zhu#, Chun-Yu Xie, Yan-Ping Kuang, Wei-Ran Chai, Edward Chin Man Lo, Wei Ye, Fei Li, Xi-Ping Feng*, Hai-Xia Lu*. Relationship between periodontal disease and male infertility: A case-control study. Oral Dis. 2021 Apr;27(3):624-631.

  17. Sicheng Wu#, Xiaoxin Ma#, Zhiyuan Zhang, Edward Chin Man LO, Xing WANG, Bao Jun TAI, De Yu HU, Huan Cai LIN, Chun Xiao WANG, Xue Nan LIU, Wen Sheng RONG, Wei Jian WANG, Yan SI, Xi Ping FENG*, Hai Xia LU*. Ethnic Disparities in Dental Caries among Adolescents in China. Journal of Dental Research, 2021 May;100(5):496-506.

  18. Xiaoxin Ma#, Yongli Wang#, Hongyu Wu, Fei Li, Xiping Feng, Yingxin Xie, Danshu Xie, Wenji Wang, Edward. Chin. Man. Lo, Haixia Lu. Periodontal health related-inflammatory and metabolic profiles of patients with end-stage renal disease: potential strategy for predictive, preventive, and personalized medicine. EPMA Journal. 2021 April (12) :117-128.

  19. Fei Li#, Ding Fu#, Danying Tao, Xiping Feng, May Chun Mei Wong, Wei Xu* and Haixia Lu*. Dynamic Observation of the Effect of Maternal Caries on the Oral Microbiota of Infants Aged 12–24 Months. Front. Cell. Infect Microbiol. / Frontiers in Cellular and Infection Microbiology. 2021 May 21;11:637394. doi: 10.3389/fcimb.2021.637394.

  20. Fei Li#, Si‑Cheng Wu#, Zhi‑Yuan Zhang, Edward Chin Man Lo, Wen‑Jia Gu, Dan‑Ying Tao, Xing Wang, Bao‑Jun Tai, De‑Yu Hu, Huan‑Cai Lin, Bo Wang, Yan Si, Chun‑Xiao Wang, Shu‑Guo Zheng, Xue‑Nan Liu, Wen‑Sheng Rong, Wei‑Jian Wang, Xi‑Ping Feng* and Hai‑Xia Lu*. Trend on dental caries status and its risk indicators in children aged 12 years in China: a multilevel analysis based on the repeated national cross-sectional surveys in 2005 and 2015. BMC Public Health. 2021, 21:2285.

  21. Chao Bi, Xiao-Lan Han, Xue-Zhu Li, Jian-Yong Sun, Yan Liu, Sheng-Zhong Duan, Hai-Xia Lu. Periodontitis aggravates renal inflammatory response in a mouse model of renal fibrosis. Oral Diseases, 2022 Mar;28(2):521-528. doi: 10.1111/odi.13764. Online ahead of print.

  22. Xiao-Xin Ma*, Xiao-Qian Meng*, Yong-Li Wang, Yuan Liu, Xue-Rui Shi, Shuai-Shao, Sheng-Zhong Duan#, Hai-Xia Lu#. NCoR1 deficiency promotes osteoclastogenesis and exacerbates periodontitis. Journal of Dental Research, 2022 Aug 18; 220345221116927. doi: 10.1177/00220345221116927. Online ahead of print.

  23. Haixia Lu*, Hongyu Wu*, Yuanmeng Yang, Xiping Feng, Xiaoxin Ma, Yingxin Xie, Danshu Xie, Wenji Wang, Edward Chin Man Lo, Wei Ye. Relationship between chronic periodontitis and inflammatory cytokines in patients undergoing maintenance hemodialysis. Clinical Oral Investigation, 2022 Jul 21. doi: 10.1007/s00784-022-04629-0. Online ahead of print.

  24. Bo-Yan Chen, Wen-Zhen Lin, Yu-Lin Li, Chao Bi, Lin-Juan Du, Yuan Liu, Lu-Jun Zhou, Ting Liu, Shuo Xu, Chao-Ji Shi, Hong Zhu, Yong-Li Wang, Jian-Yong Sun, Yan Liu, Wu-Chang Zhang, Hai-Xia Lu, Yi-Hua Wang, Qiang Feng, Fu-Xiang Chen, Chang-Qian Wang, Maurizio S. Tonetti, Ya-Qin Zhu, Huili Zhang, Sheng-Zhong Duan. Roles of oral microbiota and oral-gut microbial transmission in hypertension. Journal of Advanced Research, 2022. Online ahead of print.

  25. Relationship between chronic periodontitis and inflammatory cytokines in patients undergoing maintenance hemodialysis, Clinical Oral Investigations, 2022 Jul 21. doi: 10.1007/s00784-022-04629-0. Online ahead of print.

  26. Hai Xia LU, Dan Ying TAO, Edward Chin Man LO, Rui LI, Xing WANG, Bao Jun TAI, De Yu HU, Huan Cai LIN, Bo WANG, Yan SI, Chun Xiao WANG, Shu Guo ZHENG, Xue Nan LIU, Wen Sheng RONG, Wei Jian WANG, Xi Ping FENG. The 4th National Oral Health Survey in the Mainland of China: Background and Methodology. The Chinese Journal of Dental Research, 2018, 21(3):161-165.

  27. Li F, Zhu C, Deng F-Y, Wong M.C.M, Lu H-X, Feng X-P (2017) Herpesviruses in etiopathogenesis of aggressive periodontitis: A meta-analysis based on case-control studies. PLoS ONE 12(10): e0186373.

  28. Lu HX, Wong MCM. Perspectives of Dentists on Smoking Cessation in Hong Kong. Hong Kong Dental Journal. 2011; 8: 79-86.

  29. Wong MCM, Lu HX, Lo ECM (2011). Caries increment over 2 years in preschool children: a life course approach. Int J Paediatr Dent. 2012; 22(2): 77-84.

  30. Xu W, Lu HX, Li CR, Zeng XL. Dental caries status and risk indicators of dental caries among middle-aged adults in Shanghai, China. Journal of Dental Science. 2014; 9(2): 151-7;

  31. Gu Q, Lu HX, Feng XP. Status of the dental health care workforce in Shanghai, China. International Dental Journal. 2012; 62(6): 331-6.

  32. Chen X, Zhan JY, Lu HX, Ye W, Zhang W, Yang WJ, Feng XP. Factors associated with black tooth stain in Chinese preschool children. Clinical Oral Investigation. 2014, 18(9): 2059-2066.

  33. Chen X, Zhang Y, Lu HX, Feng XP. Factors Associated with Halitosis in White-Collar Employees in Shanghai, China. PLoS ONE. 2016, 11(5): e0155592. doi:10.1371/journal.pone.0155592

  34. Tao DY, Shu CB, Lo ECM, Lu HX, Feng XP. A Randomized Trial on the Inhibitory Effect of Chewing Gum Containing Tea Polyphenol on Caries. Journal of Clinical Pediatric Dentistry. 2013; 38(1):67-70.

  35. Wong MCM, Lau AW, Lam KF, McGrath C, Lu HX. Assessing consistency in oral health-related quality of life (OHRQoL) across gender and stability of OHRQoL over time for adolescents using Structural Equation Modeling. Community Dent Oral Epidemiol. 2011; 39(4): 325-35.