Research Interests: Pathogenesis and prevention strategies of metabolism-related reproductive abnormalities
Tao Tao, aged 45, the Deputy Director of Administration, Chief Physician and Postgraduate tutor of the Department of Endocrinology at Renji Hospital, Shanghai JiaoTong University School of Medicine, and the clinical research tutor and adjunct professor in the department of innovation in Medical Education, Faculty of Medicine at the Ottawa-Shanghai Joint School of Medicine.
The senior member of the Androgen Excess & PCOS Society of the United States, member of the Standing Committee of the Endocrine and Diabetes Branch of the Bai Qiu'en Spiritual Research Society, member of the Gestational Diabetes Group of the 8th Committee of the Chinese Medical Association Diabetes Branch, member of the 11th Committee of the Endocrine Specialist Branch of the Shanghai Medical Association, deputy leader of the Endocrine Gonadology Group of the Shanghai Medical Association, young member of the 7th Committee of the Shanghai Medical Association Diabetes, member of the Seventh Committee of the Shanghai Medical Association for Diabetes, member of the Research Sub-Committee on Psychosomatic Medicine of the Chinese Medical and Health Culture Association, member of the Standing Committee of the Endocrine and Diabetes Sub-Committee of the Bai Qiu'en Spiritual Research Association, member of the Ninth Committee of the Shanghai Medical Association for Endocrinology and Metabolism. The reviewer for Clinical Endocrinology, Frontiers in Endocrinology and other academic journals and monographs.
Has published 49 papers in national and international journals, 32 of which are SCI-indexed, including 20 papers with first or corresponding authorship. Hosted 2 National Natural Science Foundation of China (NSFC) projects, 3 Shanghai Science and Technology Commission (SSTC) projects. Participated in 1 sub-project under the National Key Research and Development Program of China, 3 projects under the National Natural Science Foundation of China (NSFC). The editor-in-chief of "Polycystic Ovary Syndrome and Endocrine Infertility" and the co-editor of 5 monographs. In 2018 was awarded the Outstanding Teacher of Residency Standardization Training in Renji Hospital. In 2005 was awarded the Outstanding Youth Reserve of Renji Hospital. Has been invited to give lectures at many academic conferences in China.
Main research directions include the study of the etiology and treatment strategies of metabolism-related reproductive abnormalities (polycystic ovary syndrome). Has visited the Department of Endocrinology at the University of Virginia School of Medicine and the Massachusetts General Hospital of Harvard University in the United States, where conducted clinical and basic research on polycystic ovary syndrome and bone metabolism.
Shan C, Zhu YC, Yu J, Zhang Y, Wang YY, Lu N, Cai J, Liu W, Tao T. Low Serum 25-Hydroxyvitamin D Levels Are Associated With Hyperandrogenemia in Polycystic Ovary Syndrome: A Cross-Sectional Study. Front Endocrinol (Lausanne). 2022 May 2;13:894935.
Tao T, Kobelski MM, Saini V, Demay MB. Adipose-specific VDR Deletion Leads to Hepatic Steatosis in Female Mice Fed a Low-Fat Diet. Endocrinology. 2022 Feb 1;163(2):bqab249.
Tao T, Zhang Y, Zhu YC, Fu JR, Wang YY, Cai J, Ma JY, Xu Y, Gao YN, Sun Y, Fan W, Liu W. Exenatide, Metformin, or Both for Prediabetes in PCOS: A Randomized, Open-label, Parallel-group Controlled Study. J Clin Endocrinol Metab. 2021 Mar 8;106(3):e1420-e1432.
Wang Y, Guo X, Xu W, Cai J, Zhang Y, Wu C, Li S, Sun Y, Liu W, Tao T. Role of Androgen in Liver Fat Content in Women: Metabolically Advantageous or Disadvantageous? Endocr Pract 2020.
Tao T, Xu H. Autophagy and Obesity-Related Reproductive Dysfunction. Adv Exp Med Biol 2020, 1207: 463-466.
Li X, Zhang T, Li S, Deng Y, Wang L, Tao T, Wang S, Gu Y, Gu W, Hong J, Liu W, Wang W, Zhang Y. Correlation between glucose metabolism and serum steroid hormones in patients with polycystic ovary syndrome. Clin Endocrinol (Oxf) 2020, 92(4): 350-357.
Tao T, Wang Y, Xu B, Mao X, Sun Y, Liu W. Role of adiponectin/peroxisome proliferator-activated receptor alpha signaling in human chorionic gonadotropin-induced estradiol synthesis in human luteinized granulosa cells. Mol Cell Endocrinol. 2019 Aug 1;493:110450.
Cai J, Zhang Y, Wang Y, Li S, Wang L, Zheng J, Jiang Y, Dong Y, Zhou H, Hu Y, Ma J, Liu W, Tao T. High Thyroid Stimulating Hormone Level Is Associated With Hyperandrogenism in Euthyroid Polycystic Ovary Syndrome (PCOS) Women, Independent of Age, BMI, and Thyroid Autoimmunity: A Cross-Sectional Analysis. Front Endocrinol (Lausanne). 2019 Apr 10;10:222.
Huang R, Xue X, Li S, Wang Y, Sun Y, Liu W, Yin H, Tao T. Alterations of polyunsaturated fatty acid metabolism in ovarian tissues of polycystic ovary syndrome rats. J Cell Mol Med. 2018 Jul;22(7):3388-3396.
Wang Y, Zhou W, Wu C, Zhang Y, Lin T, Sun Y, Liu W, Tao T. Circulating osteopontin and its association with liver fat content in non-obese women with polycystic ovary syndrome: a case control study. Reprod Biol Endocrinol. 2018 Mar 27;16(1):31.
Tao T, Wu P, Wang Y, Liu W. Comparison of glycemic control and β-cell function in new onset T2DM patients with PCOS of metformin and saxagliptin monotherapy or combination treatment. BMC Endocr Disord. 2018 Feb 27;18(1):14.
Liu Y, Li S, Tao T, Li X, Zhu Q, Liao Y, Ma J, Sun Y, Liu W. Intrafollicular fibroblast growth factor 13 in polycystic ovary syndrome: relationship with androgen levels and oocyte developmental competence. J Ovarian Res 2018, 11(1): 87
Cai J, Wu CH, Zhang Y, Wang YY, Xu WD, Lin TC, Li SX, Wang LH, Zheng J, Sun Y, Liu W, Tao T. High-free androgen index is associated with increased risk of non-alcoholic fatty liver disease in women with polycystic ovary syndrome, independent of obesity and insulin resistance. Int J Obes (Lond) 2017; 41: 1341-1347
Ju Q, Tao T, Hu T, Karadağ AS, Al-Khuzaei S, Chen W. Sex hormones and acne. Clin Dermatol. 2017 Mar-Apr;35(2):130-137.
Li S, Chu Q, Ma J, Sun Y, Tao T, Huang R, Liao Y, Yue J, Zheng J, Wang L, Xue X, Zhu M, Kang X, Yin H, Liu W. Discovery of Novel Lipid Profiles in PCOS: Do Insulin and Androgen Oppositely Regulate Bioactive Lipid Production? J Clin Endocrinol Metab. 2017 Mar 1;102(3):810-821.
Liao Y, Huang R, Sun Y, Yue J, Zheng J, Wang L, Tao T, Ma J, Li S, Liu W. An inverse association between serum soluble receptor of advanced glycation end products and hyperandrogenism and potential implication in polycystic ovary syndrome patients. Reprod Biol Endocrinol 2017 Jan 26;15(1):9
Deng Y, Zhang Y, Li S, Zhou W, Ye L, Wang L, Tao T, Gu J, Yang Z, Zhao D, Gu W, Hong J, Ning G, Liu W, Wang W. Steroid hormone profiling in obese and nonobese women with polycystic ovary syndrome. Sci Rep 2017 Oct 26;7(1):14156
Li Q, Yan Z, Kuang Y, Zhou X, Jin L, He L, Sun X, Tao T, Wang L. Genetic variations in the 3'-untranslated region of SLC18A2 are associated with serum FSH concentration in polycystic ovary syndrome patients and regulate gene expression in vitro. Hum Reprod. 2016 Sep;31(9):2150-7.
Huang R, Zheng J, Li S, Tao T, Ma J, Liu W. Characteristics and contributions of hyperandrogenism to insulin resistance and other metabolic profiles in polycystic ovary syndrome. Acta Obstet Gynecol Scand. 2015;94(5):494-500.
Huang R, Yue J, Sun Y, Zheng J, Tao T, Li S, Liu W. Increased serum chemerin concentrations in patients with polycystic ovary syndrome: Relationship between insulin resistance and ovarian volume. Clin Chim Acta 2015 ;450:366-9
Huang R, Zheng J, Li S, Tao T, Liu W. Subclinical hypothyroidism in patients with polycystic ovary syndrome: distribution and its association with lipid profiles. Eur J Obstet Gynecol Reprod Biol 2014 ;177:52-6
Huang R, Zheng J, Li S, Wang L, Tao T, Teng X, Ma J, Liu W. Variations in different polycystic ovary syndrome phenotypes in a population of Chinese Han. Endocr Connect 2014 Mar 14;3(1):Z1
Ma J, Liu LY, Wu PH, Liao Y, Tao T, Liu W. Comparison of metformin and repaglinide monotherapy in the treatment of new onset type 2 diabetes mellitus in China. J Diabetes Res 2014;2014:294017
Yang J, Gong H, Liu W, Tao T. The association of Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 gene with the metabolic characteristics in Chinese women with polycystic ovary syndrome. Int J Clin Exp Pathol. 2013 Aug 15;6(9):1894-902.
Tao T, Xu B, Liu W. Ovarian HMW adiponectin is associated with folliculogenesis in women with polycystic ovary syndrome. Reprod Biol Endocrinol. 2013 Oct 21;11:99.
Li S, Tao T, Wang L, Mao X, Zheng J, Zhao A, Liu W. The expression of 11beta-HSDs, GR, and H6PDH in subcutaneous adipose tissue from polycystic ovary syndrome subjects. Horm Metab Res 2013; 45: 802-807
Wickham EP, 3rd, Tao T, Nestler JE, McGee EA. Activation of the LH receptor up regulates the type 2 adiponectin receptor in human granulosa cells. J Assist Reprod Genet 2013; 30: 963-968
Tao T, Li S, Zhao A, Zhang Y and Liu W. Expression of the CD11c gene in subcutaneous adipose tissue is associated with cytokine level and insulin resistance in women with polycystic ovary syndrome. Eur J Endocrinol 2012; 167: 705-713
Tao T, Li S, Zhao A, Mao X and Liu W. Early impaired β-cell function in chinese women with polycystic ovary syndrome. Int J Clin Exp Pathol 2012; 5: 777-786
Tao T, Wickham EP, 3rd, Fan W, Yang J and Liu W. Distribution of adiponectin multimeric forms in Chinese women with polycystic ovary syndrome and their relation to insulin resistance. Eur J Endocrinol 2010; 163: 399-406
Hu Y, Liu W, Chen Y, Zhang M, Wang L, Zhou H, Wu P, Teng X, Dong Y, Zhou J, Xu H, Zheng J, Li S, Tao T, Hu Y, Jia Y. Combined use of fasting plasma glucose and glycated hemoglobin A1c in the screening of diabetes and impaired glucose tolerance. Acta Diabetol 2010, 47(3): 231-236.