School of Pediatrics


Yan Weihui

Associate senior physician


Research direction: Regulation of intestinal barrier in pediatric gastrointestinal diseases; prevention and management of parenteral nutrition-associated liver disease


She graduated from Zhejiang University School of Medicine in 2006 with a master's degree in pediatrics. After that, she worked at the department of gastroenterology, Children's Hospital Affiliated to Zhejiang University School of Medicine, completed the standardized residency training, and became attending in 2009. From 2011 to 2014, she studied at Shanghai Jiao Tong University School of Medicine and obtained a Ph.D. in pediatrics. Since August 2014, she has been working at the division of pediatric gastroenterology and nutrition, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine. She visited Lencer’s Laboratory as a visiting scholar at Boston Children's Hospital, Harvard Medical School from 2016-2017. In 2018, she was promoted as associate senior physician. She has been engaged in clinical, training and research work in pediatric gastroenterology and nutrition for more than 15 years. Several projects were granted, including the National Natural Science Foundation of China, the Shanghai Natural Science Foundation, and the Foundation of Municipal Health Commission. She also contributed to the formulation of several clinical guidelines or expert consensus.

Academic position: young member of Gastroenterology Group, Chinese Pediatric Society, Chinese Medical Association; young member of Parenteral and enteral Nutrition Society, Shanghai Medical Association; member of Gastroenterology Group, Pediatric gastrointestinal diseases and health care Society, Chinese Maternal and Child Health Association; member of Gastroenterology Group, Pediatric Society, Shanghai Medical Association.


  1. Lina Dai, Junkai Yan, Tian Zhang, Wei Cai*, Weihui Yan*. Butyrate promotes the adaptation of intestinal smooth muscle cells through the yes-associated protein (YAP) pathway in a rat model of short bowel syndrome, American Journal of Translational Research, 2019, 11(1): 453-462.

  2. Junkai Yan, Weihui Yan*, Wei Cai*. Fish oil-derived lipid emulsion induces RIP1-dependent and caspase 8-licensed necroptosis in IEC-6 cells through overproduction of reactive oxygen species, Lipids in Health and Disease, 2018, 17(1): 148.

  3. Yan W, Xiao Y, Zhang Y, Tao Y, Cao Y, Liu K, Cai W, Wang Y. Monogenic mutations in four cases of neonatal-onset watery diarrhea and a mutation review in East Asia. Orphanet J Rare Dis. 2021 Sep 9;16(1):383.

  4. Nan Wang#, Weihui Yan#,  Li Hong, Lina Lu, Yi Feng, Jiang Wu, Yijing Tao, Huijuan Ruan, Qingya Tang, Wei Cai, Ying Wang*. Risk factors of parenteral nutrition-associated cholestasis in very-low-birthweight infants, Journal of paediatrics and Child Health, 2020, 56(11): 1785-1790.

  5. Yan W#, Hong L#, Wang Y#, Feng Y, Lu L, Tao Y, Wu J, Ruan H, Tang Q, Cai W. Retrospective Dual-Center Study of Parenteral Nutrition-Associated Cholestasis in Premature Neonates: 15 Years' Experience. Nutr Clin Pract. 2017 Jun;32(3):407-413.

  6. Wang Y#, Yan W#, Wang J, Zhou Y, Chen J, Gu B, Cai W. Common genetic variants in GAL, GAP43 and NRSN1 and interaction networks confer susceptibility to Hirschsprung disease. J Cell Mol Med. 2018 Jul;22(7):3377-3387.