School of Pediatrics


ZHANG Jianhua

Professor, Chief physician


Mobile Phone:15000572623

Research interests: Pediatric respiratory infections, asthma, chronic cough, allergic diseases


Jianhua Zhang is a professor of pediatrics, chief physician, PhD(medical doctor), doctoral supervisor, Shanghai Jiao Tong University School of Medicine. He graduated from the Department of Pediatrics, Nanjing Medical University in 1987, and received his master's and Doctor's degrees in medicine from Soochow University in 1993 and 1999. He was a visiting scholar at the University of Hawaii School of Medicine in 2011. Currently, he is the director of Pediatric Respiratory Department (national key clinical specialty) of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.

Professor Zhang is a member of the Standing Committee of Pediatricians Branch of Chinese Medical Doctor Association and Chairman of the Children's Respiratory Committee. Member of Respiratory Group, Pediatric Branch of Chinese Medical Association, leader of children's chronic cough collaborative group. National Children's Medical Center Yangtze River Delta Pediatric Respiratory Alliance vice chairman. Standing Committee Member of Children's Health and Pharmaceutical Research Committee of China Association of Traditional Chinese Medicine, etc. He is the standing editorial board and editorial board member of Chinese Journal of Clinical Practical Pediatrics, Journal of Clinical Pediatrics, Journal of Educational Biology, and Pediatric    Pulmonology (Chinese version).

Professor Zhang has rich clinical experience in the diagnosis, treatment and research of respiratory tract infections, asthma, chronic cough, tuberculosis infection and allergic diseases in children.

Professor Zhang has undertaken research projects of the National Natural Science Foundation of China and the Shanghai Key Basic Research Project. Won the first prize of science and technology progress twice, second prize twice and third prize once by Jiangsu Provincial Health Department; Suzhou Science and Technology Progress second prize twice; Shanghai Science and Technology Progress second prize once. He has published more than 140 papers as the first author or corresponding author, 30 of which are included in SCI.


Appendix: Papers of the first author or corresponding author included in SCI in 10 years:

25. Zhu R, Mao S, Shi W, Wu L, Zhang J*. A prediction study of IL-18 and IFN-γ in glucocorticoid treatment response in infants and young children with severe Mycoplasma pneumoniae pneumonia, Transl Pediatr,2022,11(5):738-747.

24. Chen L, Xu W, Mao S, Zhu R, Zhang J*. Autoantibody of interleukin-17A induced by recombinant Mycobacterium smegmatis attenuates airway inflammation in mice with neutrophilic asthma. J Asthma, 2021,18:1-10.

23. Yongli Lv,  Jianhua Zhang* Chaoying Wang. Self-assembled chitosan nanoparticles for intranasal delivery of recombinant protein interleukin-17 receptor C (IL-17RC): preparation and evaluation in asthma mice. Bioengineered, 2021,12(1): 3029–3039.

22. Li Hua, Fen Yang, Qian Chen,Quanhua Liu,Ruoxu Ji,Haipei Liu,Jianmin Ye, Jun Zhang, Jianhua  Zhang*,Yixiao Bao*. Association of a four-gene model with allergic diseases: two-year follow-up of a birth cohort study. Immun Inflamm Dis, 2021,9(1):239-245.

21. Mengxue Chen, Yutong Gu, Quanhua Liu,Ruoxu Ji, Jianhua Zhang*, Li Hua*. Relationship of Cord Blood IgE with Maternal, Fetal and Environmental Factors in Chinese population. Allergol Immunopathol(Madr),2021,49(2):00-00.

20. Jingyang Li, Jinhong Wu, Haipei Liu, Li Hua, Quanhua Liu,Dingzhu Fang,Yi Chen,Ruoxu Ji, Jianhua Zhang*, and Wenwei Zhong*. Utility of Basophil Activation Test for predicting the outcome of wheezing in children: a pilot study. BMC immunology, 2021 Jan 6;22(1):4.

19. Yuan F, Hu R, Wang M, Zhang J*. MiR-124-3p protects against acute lung injury in young rats with septic shock via regulating p38 MAPK signaling pathway. Int J Clin Exp Med,2020,13(7):4822-4830.

18. Li W, Mao S,  Wu L, Shi W, Zhang J*, Wang Z*. Association between the PAI-1 4G/5G Gene Polymorphism and the Risk of System Lupus Erythematosus/Lupus Nephritis. Crit Rev Eukaryot Gene Expr, 2019,29(1):85-94.

17. Mao S, Fang L, Liu F, Jiang S, Wu L, Zhang J*. Leptin and chronic kidney diseases. J Recept Signal Transduct Res, 2018,38(2):89-94

16. Xu W, Chen L, Guo S, Wu L, Zhang J*. Intranasal Administration of Recombinant Mycobacterium smegmatis Inducing IL-17A Autoantibody Attenuates Airway Inflammation in a Murine Model of Allergic Asthma, 2016,11(3):e0151581.

15. Zhang Y, Zhang J*. Preparation of budesonide nanosuspensions for pulmonary delivery: Characterization, in vitro release and in vivo lung distribution studies. Artif Cells Nanomed Biotechnol, 2016, 44(1):285-9.

14. Mao S, Ren X, Zhang J*. The emerging role of fibroblast growth factor 21 in diabetic nephropathy. J Recept Signal Transduct Res, 2016,36(6):586-592.

13. Mao S*, Shen H, Zhang J*. Systemic lupus erythematosus and malignancies risk. J Cancer Res Clin Oncol, 2016,142(1):253-62

12. Mao S*. Zhang J*. Role of complement in glomerular diseases.J Recept Signal Transduct Res,2016, 36(3):319-25.

11. Guo S, Wu LX, Jones CX, Chen L, Hao CL, He L*, Zhang JH*. Allergic airway inflammation disrupts interleukin-17 mediated host defense against streptococcus pneumoniae infection. Int Immunopharmacol, 2016,31:32-8.

10. Mao S*, Zhang J*. The emerging role of hepatocyte growth factor in renal diseases. J Recept Signal Transduct Res, 2016 ,36(3):303-9.

9. Mao S*, Zhang J*. Risk factors for renal damage in Henoch-Schonlein purpura:a meta analysis. Int J Clin Exp Med, 2016, 9(2):3607-3613.

8. Mao S*, Yan B, Zhang J*. Association of transforming growth factor-β1 polymorphisms with the risk of chronic kidney diseases. Ren Fail, 2015,37(10):304-11.

7. Mao S, Zhang J*. Role of autophagy in chronic kidney diseases. Int J Clin Exp Med, 2015, 8(12):22022-9.

6. Chen L, Guo S, Wu L, Fan X, Ma H, Wu K, Wu J, Zhang J*. IL-17A Autoantibody Induced by Recombinant Mycobacterium smegmatis Expressing Ag85A-IL-17A Fusion Protein. App Biochem Biotechnol, 2015,176(7):2018-2026.

5. Chen L, Guo S, Wu L, Hao C, Xu W, Zhang J*. Effects of recombinant IL-17F intranasal inoculation against Streptococcus pneumoniae infection in a murine model. Biotechnol Appl Biochem, 2015, 62(3):393-400.

4. Chen L, Guo S, Xu M, Wu LX, Zhang JH*.Effect of diclofenac on the pharmacokinetics of moxifloxacin in rats. Drug Res (Stuttg), 2014,64(7):343-7.

3. Jin R, Guo S, Wang MY, Li YH, Wu LX, Ma H, Lowrie DB, Fan XY, Zhang JH*. Administration of mycobacterial Ag85A and IL-17A fusion protein attenuates airway inflammation in a murine model of asthma. Int Immunopharmacol. 2013,17(4):1067-74.

2. Zhang JH*, Guo S, Xu M, Wu LX. A simply HPLC method for determination of cefpodoxime in Chinese volunteer and pharmacokinetic study. Drug Res (Stuttg), 2013,63(8):435-8.

1. Jin R, Guo S, Wu L, Fan X, Ma H, Lowrie DB, Zhang J*.Il17A autoantibody induced by recombinant protein Ag85A-Il17A. Appl Biochem Biotechnol,2013,169(2):502-10.