College of Basic Medical Sciences

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WANG Jing

Email: jingwang@shsmu.edu.cn

Tel: 13816893660

Research Field: Neutrophil, inflammation, imaging

Personal Introduction

  • Jing Wang received her Ph.D. in Medical Science from Osaka University in 2011 and continued as a postdoctoral fellow in Osaka University (2011~2013) and University of Calgary (2013~2016), where she used intravital imaging to study how neutrophils responde to sterile injury in vivo at the Laboratory of Dr. Paul Kubes. She joined Shanghai Jiao Tong University and Shanghai Institute of Immunology as a Principal Investigator since May, 2018. Her main research interest is to understand how innate immune cells such as neutrophils and macrophages recognize and respond to the presence of "danger agents" and how the specific tissue environment cues may affect such responses.

Publications

  • Zhao D, Yang F, Wang Y, Li S, Li Y, Hou F, Yang W, Liu D, Tao Y, Li Q, Wang J*, He F*, Tang L*. ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection. J Clin Invest. 2021 Dec 7: e150489 *共同通讯

  • Li D, Xiong W, Wang Y, Feng J, He Y, Du J, Wang J, Yang M, Zeng H, Yang Y, Wu N, Chen S*, Dong Z*. SLAMF3 and SLAMF4 are immune checkpoints that constrain macrophage phagocytosis of hematopoietic tumors. Sci Immunol. 2022 Jan 21;7(67)

  • Wang C, Zhang L, Sun Z, Yuan X, Wu B, Cen J, Cui L, Zhang K, Li C, Wu J, Shu Y, Sun W, Wang J, Hui L. Dedifferentiation-associated inflammatory factors of long-term expanded human hepatocytes exacerbate their elimination by macrophages during liver engraftment. Hepatology. 2022 Mar 1.

  • Li G, Wang M, Ding T, Wang J, Chen T, Shao Q, Jiang K, Wang L, Yu Y, Pan F, Wang B, Wei X, Qian J, Zhan C. cRGD enables rapid phagocytosis of liposomal vancomycin for intracellular bacterial clearance. J Control Release. 2022 Apr; 344

  • Huan Wang, Tianhao Ding, Juan Guan, Xia Liu, Jing Wang, Pengpeng Jin, Shuangxing Hou, Weiyue Lu, Jun Qian, Weiping Wang, and Changyou Zhan. Interrogation of folic acid-functionalized nanomedicines: The regulatory roles of plasma proteins reexamined. ACS Nano 2020

  • Xinyu Yang, Xiaoye Cheng, Yiting Tang, Xianhui Qiu, Zhongtai Wang, Guang Fu, Jianfeng Wu, Haixia Kang, Jing Wang, Haichao Wang, Fangping Chen, Xianzhong Xiao, Timothy Billiar, Ben Lu. The role of type 1 interferons in Gram-negative bacteria-induced coagulation. Blood 135 (14), 1087-1100, 2020

  • Bartneck M, Wang J. Therapeutic Targeting of Neutrophil Granulocytes in Inflammatory Liver Disease. Front. Immunol.,10:2257, 2019

  • Wang J. Neutrophils in tissue injury and repair. Cell Tissue Res 371(3):531-539, 2018

  • Wang J*, Hossain M*, Thanabalasuriar A, Gunzer M, Meininger C, Kubes P. Visualizing the Function and Fate of Neutrophils in Sterile Injury and Repair. Science 358(6359): 111-116, 2017 * Contribute equally