College of Basic Medical Sciences

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Svetoslav Georgiev Chakarov

Email: svetoslav_chakarov@shsmu.edu.cn

Tel: 63846590-776796

Research Field: Myeloid cell biology and  metabolism lab

Personal Introduction

  • 2021.4-now Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai Institute of Immunology (SII), Research Fellow

  • 2019.3-2021.4 Singapore Immunology network, Research Scientist

  • 2014.1-2019.3 Singapore Immunology network, PostDoc

  • 2009.9-2013.12 University Paul Sabatier (Toulouse, France), Ph.D degree

  • 2007.9-2009.7 University Paul Sabatier (Toulouse, France), Master degree

  • 2004.9-2007.7 University Paul Sabatier (Toulouse, France), university degree

Scientific Research Projects

  • Estern scholar,2021.1-2023.12

  • Foreign Experts Project of Shanghai Science and Technology Commission,150k,2021.1-2021.12

  • Start up from SJTU,5 million,2021.1-2025.12

  • Key research project of SII (ab-seq),300k,2021.1-2021.12

  • Key research project of SII (Mucosal immunity),350k,2021.1-2021.12

  • Special funds for high-level local universities from SJTU,24k,2021.11-2021.12

Publications

  • Chakarov S, Lim HY, Tan L, Lim SY, See P, Lum J, Zhang XM, Foo S, Nakamizo S, Duan K, Kong WT, Gentek R, Balachander A, Carbajo D, Bleriot C, Malleret B, Tam JKC, Baig S, Shabeer M, Toh SES, Schlitzer A, Larbi A, Marichal T, Malissen B, Chen J, Poidinger M, Kabashima K, Bajenoff M, Ng LG, Angeli V, Ginhoux F. Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches. Science. 2019 Mar 15;363(6432). pii: eaau0964.

  • Fujita K, Chakarov S, Kobayashi T, Sakamoto K, Voisin B, Duan K, Nakagawa T, Horiuchi K, Amagai M,Ginhoux F, Nagao K. Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen. PNAS. 2019 Jul 16;116(29):14714-14723.

  • Liu Z, Gu Y, Chakarov S, Bleriot C, Kwok I, Chen X, Shin A, Huang W, Dress RJ, Dutertre CA, Schlitzer A, Chen J, Ng LG, Wang H, Liu Z, Su B, Ginhoux F. Fate mapping via Ms4a3-expression history traces monocyte-derived cells. Cell. 2019 Sep 5 178, 1509-1525.

  • Chakarov S & Fazilleau N. Monocyte-derived dendritic cells promote T follicular helper cell differentiation. EMBO Mol Med. 2014 May;6(5):590-603.

  • Chakarov S & Fazilleau N. Tracking by flow cytometry antigen-specific follicular helper T cells in wild-type animals after protein vaccination. Methods Mol Biol. 2015 1291:39-47.