SVETOSLAV Georgiev Chakarov
Email: svetoslav_chakarov@shsmu.edu.cn
Tel: 63846590-776796
Research Field: Myeloid cell biology and metabolism lab
Biography
2021.4-now Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai Institute of Immunology (SII), Research Fellow
2019.3-2021.4 Singapore Immunology network, Research Scientist
2014.1-2019.3 Singapore Immunology network, PostDoc
2009.9-2013.12 University Paul Sabatier (Toulouse, France), Ph.D degree
2007.9-2009.7 University Paul Sabatier (Toulouse, France), Master degree
2004.9-2007.7 University Paul Sabatier (Toulouse, France), university degree
Scientific Research Projects
Estern scholar，2021.1-2023.12
Foreign Experts Project of Shanghai Science and Technology Commission，150k，2021.1-2021.12
Start up from SJTU，5 million，2021.1-2025.12
Key research project of SII （ab-seq），300k，2021.1-2021.12
Key research project of SII (Mucosal immunity)，350k，2021.1-2021.12
Special funds for high-level local universities from SJTU，24k，2021.11-2021.12
Publications
Chakarov S, Lim HY, Tan L, Lim SY, See P, Lum J, Zhang XM, Foo S, Nakamizo S, Duan K, Kong WT, Gentek R, Balachander A, Carbajo D, Bleriot C, Malleret B, Tam JKC, Baig S, Shabeer M, Toh SES, Schlitzer A, Larbi A, Marichal T, Malissen B, Chen J, Poidinger M, Kabashima K, Bajenoff M, Ng LG, Angeli V, Ginhoux F. Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches. Science. 2019 Mar 15;363(6432). pii: eaau0964.
Fujita K, Chakarov S, Kobayashi T, Sakamoto K, Voisin B, Duan K, Nakagawa T, Horiuchi K, Amagai M,Ginhoux F, Nagao K. Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen. PNAS. 2019 Jul 16;116(29):14714-14723.
Liu Z, Gu Y, Chakarov S, Bleriot C, Kwok I, Chen X, Shin A, Huang W, Dress RJ, Dutertre CA, Schlitzer A, Chen J, Ng LG, Wang H, Liu Z, Su B, Ginhoux F. Fate mapping via Ms4a3-expression history traces monocyte-derived cells. Cell. 2019 Sep 5 178, 1509-1525.
Chakarov S & Fazilleau N. Monocyte-derived dendritic cells promote T follicular helper cell differentiation. EMBO Mol Med. 2014 May;6(5):590-603.
Chakarov S & Fazilleau N. Tracking by flow cytometry antigen-specific follicular helper T cells in wild-type animals after protein vaccination. Methods Mol Biol. 2015 1291:39-47.
