Biography

Deng Xiaobei, associate professor of Shanghai Jiao Tong University School of Public Health. She got her Ph.D of cell biology from University of Chinese Academy of Sciences in 2013. And then, she went to Tongji University School of Medicine to do postdoctoral research from 2013 to 2015. Since 2015, she has worked in Shanghai Jiao Tong University School of Medicine. Dr. DENG′s main research focused on the mechanism of atmospheric particulate matter PM2.5 induced lung cancer. As a principal investigator, she has participated in several research funds, such as General Program of National Natural Science Foundation of China, Youth Science Foundation Project of National Natural Science Foundation of China, and China Postdoctoral Science Foundation. She has published more than 20 academic papers as co-author.

EDUCATION

• 2013-2015       Postdoctoral Associate (Translational Neurodegeneration), Tongji University School of Medicine, Shanghai, China

• 2008-2013      Ph.D. (Cell biology), University of Chinese Academy of Sciences, Beijing, China

• 2006-2008      M.Sc. (Microbiology), Wuhan University Wuhan, China

• 2002-2006      Bachelor (Biotechnologies), Qingdao University, Qingdao,China

PROFESSIONAL EXPERIENCE

• 2015-2019   Lecturer, School of Public Health, Shanghai Jiao Tong University, Shanghai, P.R. China

• 2020-press   Associate Professor, School of Public Health, Shanghai Jiao Tong University, Shanghai, P.R. China

RESEARCH PROJECTS

Participate in scientific project as principal investigator

• The national natural science fund projects, #21777099, ￥650,000, 2018/01-2021/12.

• New young teacher launch program of Shanghai Jiao Tong University, ￥200,000, 2016/01-2018/12.

• The national natural science fund projects - Youth programs, #81401046, ￥220,000, 2015/01-2017/12.

• The first prize scholarship of China Postdoctoral Science Foundation (#56), #2014M560354, ￥80,000, 2014/03-2015/09.

• The scholarship of China Postdoctoral Science special Foundation (#8), #2015T80454, ￥150,000, 2015/01-2015/09.

Participate in scientific project as participator

• The national natural science fund projects - Youth programs, #81602929, ￥180,000, 2017/01-2019/12.

• The national natural science fund projects - Youth programs, #81501172, ￥210,000, 2016/01-2018/12.

• The national natural science fund projects, #81471936, ￥800,000, 2015/01-2018/12.

• The national natural science fund projects- Youth programs, #81401704, ￥230,000, 2015/01-2017/12.

• The national natural science fund projects- Youth programs, #31400926, ￥220,000, 2015/01-2017/12.

• Major national scientific research projects, #2014CB965000,￥1,5000,000, 2014/01-2018/12.

• The national natural science fund projects，#21377127, ￥820,000, 2013/01-2016/12.

PUBLICATIONS

1. Lefei Han, Shi Zhao, Peihua Cao, Marc K C Chong, Jingxuan Wang, Daihai He, Xiaobei Deng*, Jinjun Ran*. How Transportation Restriction Shapes the Relationship Between Ambient Nitrogen Dioxide and COVID-19 Transmissibility: An Exploratory Analysis. Front Public Health . 2021, 29;9:697491. doi: 10.3389/fpubh.2021.697491. eCollection 2021.(*co-corresponding author)

2. Jian Wang, Tengfei Ma, Ding Ma, Huimin Li, Li Hua, Qing He, and Xiaobei Deng*. The Impact of Air Pollution on Neurodegenerative Diseases. Ther Drug Monit. 2021, 43(1):69-78.  (*responding author)

3. Zihan Xu, Ning Wang, Ye Xua, Li Hua, Dan Zhou, Min Zheng* , Xiaobei Deng*.Effects of chronic PM2.5 exposure on pulmonary epithelia: Transcriptome analysis of mRNA-exosomal miRNA interactions. Toxicology Letters 316 (2019): 49-59. (*co-corresponding author)

4. Zihan Xu, Wenjun Ding* and Xiaobei Deng*. PM2.5, Fine Particulate Matter: A Novel Player in the EpithelialMesenchymal Transition?Front. Physiol. 10:1404. doi: 10.3389/fphys.2019.01404. (*co-corresponding author)

5. Zihan Xua#, Zilin Lia#, Ziyi Liao#, Sumeng Gao, Li Hua, Xiaofei Ye, Yu Wang, Shan Jiang, Ning Wangd, Dan Zhou*, Xiaobei Deng*. PM2.5 induced pulmonary fibrosis in vivo and in vitro, Ecotoxicology and Environmental Safety. 2019, 171:112-121. (*co-corresponding author)

6. WANG Hao#, JIANG Shan#, GONG Yang-ming, LIU Yan, HUA Li, Xiaobei Deng*, Atmospheric fine particulate matter cause Alzheimer’s disease through the olfactory bulb pathway：a review of recent studies，Journal of Shanghai Jiaotong University (Medical Science), 2019. (*Corresponding author)

7. Xiao Yu#, Xiaofei Ye#, Hongyan Lin, Nannan Feng, Sumeng Gao, Xiaohong Zhang, Yu Wang, Herbert Yu, Xiaobei Deng*, Biyun Qian* Knockdown of long non-coding RNA LCPAT1 inhibits autophagy in lung cancer, Cancer Biology & Medicine. (2018) (*co-corresponding author)

8. Kangmu Ma#, Xiaobei Deng#, Xiaohuan Xia, Xinrui Qi, Yongxiang Wang, Yuju Li, Yizhao Ma, Qiang Chen, Hui Peng, Jianqing Ding, Yunlong Huang, Changhai Tian, Jialin C. Zheng, Direct Conversion of Mouse Astrocytes into Neural Progenitor Cells and Specific Lineages of Neurons. Translational Neurodegeneration. (2018) (#co-First author)

9. Xiaobei Deng, Nannan Feng, Min Zheng, Xiaofei Ye, Hongyan Lin, Xiao Yu, Zhihua Gan, Zheng Fang, Huan Zhang, Ming Gaod, Zhi-jie Zheng, Herbert Yu, Wenjun Ding**, Biyun Qian*. PM2.5 exposure-induced autophagy is mediated by lncRNA loc146880 which also promotes the migration and invasion of lung cancer cells, Biochimica et Biophysica Acta, 2017, 1861(2), 112-125 (First author)

10. Xiaobei Deng, Fang Zhang, Lijuan Wang, Wei Rui, Fang Long, Yong Zhao*,  Deliang Chen, Wenjun Ding*, Airborne Fine Particulate Matter Induces Multiple Cell Death Pathways in Human Lung Epithelial Cells, Apoptosis, 2014, 19(7), 1099-1112 (First author)

11. Xiaobei Deng, Wei Rui, Fang Zhang*, Wenjun Ding*, PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells, Cell Biology and Toxicology, 2013, 29(3), 143-157 (First author)

12. Xiaobei Deng, Fang Zhang, Wei Rui, Fang Long, Lijuan Wang, Zhaohan Feng*, Deliang Chen, Wenjun Ding*, PM2.5-induced Oxidative Stress Triggers Autophagy in Human Lung Epithelial A549 Cells, Toxicology in Vitro, 2013, 27(6), 1762-1770 (First author)