YUAN Weijie
Professor (T2)（four-tier system）/Chief Physician/Doctoral Supervisor
Academic leader of Department of Nephrology, Shanghai General Hospital
Email: ywj4169@163.com
Tel: 021-
Research Interests: Pathogenesis of hepatitis B associated glomerulonephritis; Chronic kidney disease and intestinal microecology; Nutritional therapy for chronic kidney disease
Biography
YUAN Weijie, Academic leader of Department of Nephrology, Shanghai General Hospital, is a leading scholar of nephrology. He was selected into “Shanghai Leading Talent Plan”in 2016. And he qualified for the State Council Special Allowance.
In the past years, he has been awarded four NSF surface projects and another 18 funds. He has published more than 400 papers in authoritative journals in his field, such as American Society of Nephrology, Cell Discovery, and Kidney International. He has been awarded the honor of Chinese medical science and technology(first), 4 items of the PLA general logistics department of science and technology progress prize(first) and other honorary titles.
Selected Publications
Gang Tang, Haochen Guan, Zhiyong Du, Weijie Yuan. Comprehensive Analysis of the Butyrate-Metabolism-Related Gene Signature in Tumor Microenvironment-Infiltrating Immune Cells in Clear Cell Renal Cell Carcinoma. Front Cell Dev Biol. 2022;10:816024.
Haochen Guan#, Nan Zhu#, Gang Tang #, Yi Du, Ling Wang, Weijie Yuan. DNA methyltransferase 1 knockdown reverses PTEN and VDR by mediating demethylation of promoter and protects against renal injuries in hepatitis B virus-associated glomerulonephritis. Cell Biosci. 2022;12(1):98.
Dan-Qin Sun, Ting-Yao Wang, Kenneth I Zheng, Hao-Yang Zhang, Xiao-Dong Wang, Giovanni Targher, Christopher D Byrne, Yong-Ping Chen, Wei-Jie Yuan, Yan Jin, Ming-Hua Zheng. The HSD17B13 rs72613567 variant is associated with lower levels of albuminuria in patients with biopsy-proven nonalcoholic fatty liver disease. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2021;31(6):1822-31.
Yi Du, Yi-Tong Yang, Gang Tang, Jie-Shuang Jia, Nan Zhu, Wei-Jie Yuan. Butyrate alleviates diabetic kidney disease by mediating the miR-7a-5p/P311/TGF-β1 pathway. Faseb j, 2020. 34(8): p. 10462-10475.
Haochen Guan, Zhi Geng, Weijie Yuan, Bowen Chang. Association of Serum Uric Acid Levels in Meige's Syndrome. Front Neurosci. 2021;15:755056.
Gang Tang, Yi Du, Haochen Guan, Jieshuang Jia, Nan Zhu, Yuping Shi, Shu Rong, Weijie Yuan. Butyrate ameliorates skeletal muscle atrophy in diabetic nephropathy by enhancing gut barrier function and FFA2-mediated PI3K/Akt/mTOR signals. British journal of pharmacology. 2022;179(1):159-78.
