Biography

• Dingliang Zhu is lifetime Professor of Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine. He graduated from Shanghai Second Military Medical University in 1966, received his Master’s degree from Shanghai Second Medical College in1981 and PhD from University of Paris VI, France in1992. He was a visiting scientist in Department of Anatomy and Cell Biology at University of North Carolina at Chapel Hill (1986-1988) and the research units of INSERM and CNRS, France (1988-1995). In 1996, he joined Shanghai Institute of Hypertension (SIH), and  became Director of the Department of Cellular and Molecular Biology, Director of SIH (1998-2011) and Chief of the Department of Hypertension in Ruijin Hospital (2002-2008). In 2005, he was elected the vice-president of Chinese Hypertension League (2005-2017).

• Dr. Zhu has devoted to the basic, clinical and community research of hypertension. One of his main research interest is the mechanism of vascular remodeling. In 1999, he established Shanghai Key Laboratory of Vascular Biology. His another interest is the molecular genetics of hypertension. He led to build a huge sample of hypertension genetic biobank. Since 2011, he has expanded his research to community prevention of hypertension. He is currently Director of the Center for Hypertension Management in Community, SIH.

• Dr. Zhu has published over 300 publications including 170 papers in international journals and won 6 prizes for science and technology at national level and Shanghai municipal level.

Publications

First or corresponding author:

1. Zhu DL, Herembert T, Marche P: Increased proliferation of adventitial fibroblasts from spontaneously hypertensive rat aorta.

   J Hypertens.  1991, 9:1161-1168.

2. Zhu DL, Wang HY, Xiong MM, He X, Chu SL, Jin L, Wang GL, Yuan WT, Zhao GS, Boerwinkle E, Huang W: Linkage of hypertension to chromosome 2q14-q23 in Chinese families.

   J Hypertens.   2001; 19(1):55-61.

3.  Kato N, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, Tay WT, Chen CH, Zhang Y, Yamamoto K, Katsuya T, Yokota M, Kim YJ, Ong RT, Nabika T, Gu D, Chang LC, Kokubo Y, Huang W, Ohnaka K, Yamori Y, Nakashima E, Jaquish CE, Lee JY, Seielstad M, Isono M, Hixson JE, Chen YT, Miki T, Zhou X, Sugiyama T, Jeon JP, Liu JJ, Takayanagi R, Kim SS, Aung T, Sung YJ, Zhang X, Wong TY, Han BG, Kobayashi S, Ogihara T#, Zhu D# (co- corresponding), Iwai N#, Wu JY#, Teo YY#, Tai ES#, Cho YS#, He J#. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in East Asians。

   Nat Genet. 2011;43(6):531-538.

4. Chen CT, Li Y, Zhang J, Wang Y, Ling HW, Chen KM, Gao PJ, Zhu DL (corresponding) . Association between ambulatory systolic blood pressure during the day and asymptomatic intracranial arterial stenosis.

   Hypertension  2014;63(1):61-67.

5. Wang Y, Chen L, Fu C, Wang Y, An D, Zhang J, Tang X, Li Y, Zhu D (corresponding). Associations between various attended automated office blood pressure estimations and all-cause and cardiovascular mortality: Minhang study.

   J Hypertens.  2020;38(6):1072-1079.

Co-author:

• Ke yuehai , Su Bing, Song Xiufeng, Lu Daru, Chen Lifeng, Li Hongyu, Qi Chunjian, Marzuki Sangkot, Deka Ranjan, Underhill Peter, Xiao Chunjie, Shriver Mark, Jeff Lell, Wallace Douglas Wallace, Wells R Spencer, Seielatad Mark, Oefner Peter, Zhu Dingliang, Jin Jianzhong, Huang Wei, Chakraborty Ranajit, Chen Zhu, Jin Li : African Origin of mordern humans in east asia : a tale of 12000 Y chromosomes.

  Science  2001 ;292(5519) :1151-1153

• Huo Y, Li J, Qin X, Huang Y, Wang X, Gottesman RF, Tang G, Wang B, Chen D, He M, Fu J, Cai Y, Shi X, Zhang Y, Cui Y, Sun N, Li X, Cheng X, Wang J, Yang X, Yang T, Xiao C, Zhao G, Dong Q, Zhu D, Wang X, Ge J, Zhao L, Hu D, Liu L, Hou F. Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China, The CSPPT randomized clinical trial.

  JAMA.  2015; 313(13):1325-1335.