Tier 2 Professors

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Chen Nan

Professor, Dept of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University; Director of Institute of Nephrology, Shanghai Jiao Tong University

Email: cnrj100@126.com

Tel: 021-

Research Interests: Basic and clinical research of kidney diseases

Biography

  • Professor Nan Chen is the director of the Institute of Nephrology, Shanghai Jiao Tong University, and a tenured professor in the Ruijin Hospital, Shanghai Jiao Tong University School of Medicine. Dr. Chen was elected as an Academician of the French National Academy of Medicine (correspondence). She was the Vice President of Chinese Society of Nephrology from 2005 to 2012, the Vice President of Chinese Medicine Association of Nephrology and President, the President of Shanghai Medical Association Nephrology Branch. She currently serves as president of China Medicine Education Association of Nephrology, Shanghai Society of Nephrologists and the Vice President of Shanghai Society of Rare Disease. She is both a clinician and well-known physician-scientist. She has published more than 300 papers in international peer-reviewed academic journals, including New England Journal of Medicine, received more than 30 grants including National Natural Scientific Foundation of China, National 973 program, Mega-projects of Science Research for the 12th Five-Year Plan, Specific-Fund of Ministry of Health P.R China and et al and multiple scientific awards for her research projects including American NKF’s International Distinguished Medal Recipient (2012), First Prize, Scientific advanced Prize awarded by Chinese ministry of Public health (2018) and Pinner Award for north and east Asia(2021) et al, and leads a research team at Ruijin Hospital.

Representative Publications

  1. Chen N, Hao C, Liu BC, Lin H, Wang C, Xing C, Liang X, Jiang G, Liu Z, Li X, Zuo L, Luo L, Wang J, Zhao MH, Liu Z, Cai GY, Hao L, Leong R, Wang C, Liu C, Neff T, Szczech L, Yu KP. Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis. N Engl J Med. 2019;381(11):1011‐1022.

  2. Chen N, Hao C, Peng X, Lin H, Yin A, Hao L, Tao Y, Liang X, Liu Z, Xing C, Chen J, Luo L, Zuo L, Liao Y, Liu BC, Leong R, Wang C, Liu C, Neff T, Szczech L, Yu KP. Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis. N Engl J Med. 2019;381(11):1001‐1010.

  3. Xie J, Liu L, Mladkova N, Li Y, Ren H, … Kleta R, Chen N, Kiryluk K. The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis. Nat Commun. 2020;11(1):1600.

  4. Xie J, Hao X, Azeloglu EU, Ren H, Wang Z, Ma J, Liu J, Ma X, Wang W, Pan X, Zhang W, Zhong F, Li Y, Meng G, Kiryluk K, He JC, Gharavi AG, Chen N. Novel mutations in the inverted formin 2 gene of Chinese families contribute to focal segmental glomerulosclerosis. Kidney Int. 2015 Sep;88(3):593-604.

  5. Xie J, Wu X, Ren H, Wang W, Wang Z, Pan X, Hao X, Tong J, Ma J, Ye Z, Meng G, Zhu Y, Kiryluk K, Kong X, Hu L, Chen N. COL4A3 mutations cause focal segmental glomerulosclerosis. J Mol Cell Biol. 2014 Dec;6(6):498-505.

  6. Xie J, Lv J, Wang W, Li G, Liu Z, Chen H, Xu F, Sun J, Ouyang Y, Zhang X, Yang M, Shi M, Zhang W, Ren H, Kiryluk K, Zhang H, Chen N. Kidney Failure Risk Prediction Equations in IgA Nephropathy: A Multicenter Risk Assessment Study in Chinese Patients. Am J Kidney Dis. 2018;72(3):371‐380.

  7. Li X, Ren H, Zhang Q, Zhang W, Wu X, Xu Y, Shen P, Chen N. Mycophenolate mofetil or tacrolimus compared with intravenous cyclophosphamide in the induction treatment for active lupus nephritis. Nephrol Dial Transplant. 2012 Apr;27(4):1467-72.

  8. Xie J, Kiryluk K, Ren H, Zhu P, Huang X, Shen P, Xu T, Chen X, Chen N. Coiled versus straight peritoneal dialysis catheters: a randomized controlled trial and meta-analysis. Am J Kidney Dis. 2011 Dec;58(6):946-55.

  9. Xu J, Wang W, Shi H, Chen S, Liu Z, Li W, Zhang J, Li Y, Chen N. Chronic kidney disease is prevalent in Chinese patients admitted with verified cerebrovascular lesions and predicts short-term prognosis. Nephrol Dial Transplant. 2011 Aug;26(8):2590-4.

  10. Nan Chen, Weiming Wang, Yanping Huang, Pingyan Shen, Daoling Pei,Haijin Yu, Hao Shi, Qianying Zhang, Jing Xu, Yilun Lv and Qishi Fan. Community-based on CKD subjects and the associated risk factors.Nephrol Dial Transplant (2009) 24:2117-2123