Biography

• Dr. Li graduated from the Shanghai First Medical College in 1973. He received his master’s degree from Shanghai Medical University 1988, and his doctor’s degree in the Lund University in Sweden in 1993. From 1994 to 1995, Dr. Li pursued a post-doctoral program in the field of interventional neuroradiology as a visiting scholar in the University of Milanin,Italy.

• From September 1973 to November 1989, Dr. Li served as an residency and attending doctor of the radiology department of Huashan Hospital in Shanghai. Dr. Li served as a chief doctor and professor since January 1992. From January 2000 to May 2018, he served as the chairman and doctoral supervisor of the department of diagnostic and neoro-interventional radiology of Shanghai Sixth People’s Hospital. He retired and got an emeritus professor in 2019.

• Dr.Li’s research interests lies in non-invasive imaging diagnosis and micro-invasive therapy for cerebral vascular diseases. He did a lot of work with MRA imaging in the diagnosis of cerebral aneurysms and spinal vascular diseases, and was also a principal of development and clinical application of Willis covered stent. He published over 150 scientific papers at international scientific journal and 9 books in the area of diagnostic and interventional neuroradiology.

PUBLICATIONS

1. Li MH ,Holtas S. MR imaging of spinal neurofibromatosis. Acta Radiologica 1991;32:279-285

2. Li MH, Holtas S. MR imaging of spinal intramedullary tumors. Acta Radiologica 1991;32:505-513

3. Li MH, Holtas S, Larsson EM. MR imaging of spinal lymphoma. Acta Radiologica 1992;33:338-342

4. Li MH, Holtas S, Larsson EM. MR imaging of intradural extramedullary tumors. Acta Radiologica 1992;33:207-212

5. Li MH, Holtas S, Larsson EM. MRI of extraldural spinal tumors at 0.3T. Neuroradiology 1993;35:370-374.

6. Scotti G, Li MH, Righi C, Simionato F, Rocca A. Endovascular treatment of bacterial intracranial aneurysms. Neuroradiology 1996;38(2): 186-189

7. Li MH, Li WB, Pan YP, Fang C, Wang W. Persistent primitive trigeminal artery associated with aneurysm: two case reports and review of the literature. Acta Radiologica 2004;45(6):664-668

8. Li MH，Gao BL，Fang C, Gu BX, Cheng YS, Wang W, Scotti G. Angiographic follow-up of cerebral aneurysms treated with Guglielmi detachable coils: an analysis of 162 cases with with 173 aneurysms. AJNR Am J Neuroradiology 2006;27(5): 1107-1112

9. Li MH，Gao BL，Fang C, Cheng YS, Li YD, Wang J, Xu GP. Prevention and management of intraprocedural rupture of intracranial aneurysm with detachable coils during embolization. Neuroradiology 2006;48(12): 907-915

10. Gao BL，Li MH, Wang YL, Fang C. Delayed coil migration from a small wide-necked aneurysm after stent-assisted embolization. Neuroradiology 2006;48(5):333-337

11. Li MH，Gao BL，Wang YL, Fang C, Li YD. Management of pseudoaneurysms in the CICA with covered stents specially designed for use in the intracranial vasculature : technical notes. Neuroradiology 2006;48(11): 841-846

12. Li MH, Li YD, Fang C, Gu BX, Cheng YS, Wang YL, Gao BL, Zhao JG, Wang J, Li M. Endovascular treatment of giant or very large intracranial aneurysms with different modalities: an analysis of 20 cases. Neuroradiology 2007; 49(10):819-828

13. Li MH, Li YD, Gao BL, Fang C, Luo QY, Cheng YS, Xie ZY, Wang YL, Zhao JG, Li Y, Wang W, Zhang BL, Li M. A new covered stent designed for intracranial vasculature: application in the management of pseudoaneurysms of the cranial internal carotid artery. AJNR Am J Neuroradiol. 2007; 28(8):1579-1585

14. Li MH，Li WB，Fang C, Gao BL. Transarterial embolization with Berenstein liquid coils and N-butyl cyanoacrylate in a vein of Galen aneurysmal malformation. Korean J Radiol. 2007;8(2):164-168

15. Tan HQ, Li MH, Wu CG, Gu YF, Zhang H, Fang C. Percutaneous vertebroplasty for eosinophilic granuloma of the cervical spine in a child. Pediatr Radiol. 2007;37:1053-1057

16. Li MH, Zhu YQ, Fang C, Wang W, Zhang PL, Cheng YS, Tan HQ, Wang JB. The feasibility and efficacy of treatment with a Willis covered stent in recurrent intracranial aneurysms after coiling. AJNR Am J Neuroradiol. 2008;29:1395-1400

17. Wang JB, Li MH, Fang C, Wang W, Cheng YS, Zhang PL, Du ZY, Wang J. Endovascular treatment of giant intracranial aneurysms with willis covered stents: technical case report. Neurosurgery 2008;62(5):E1176-1177

18. Tan HQ, Li MH, Zhu YQ，Fang C, Wu CG, Cheng YS, Wang J, Xie J, Zhang H. Surgical Construction of a Novel Simulated Carotid Siphon in dogs. J Neurosurg. 2008;109(6) : 1173-1178

19. Li MH, Tan HQ, Fang C, Zhu YQ, Wang W, Wang J, Cheng YS. Transarterial embolotherapy of Dural Carotid-Cavernous Fistula with low concentration n-Butyl-Cyanoacrylate. Acta neurochir. 2008;150(11):1149-1156

20. Fang C, Li MH, Tan HQ, Zhang PL, Zhou B. Endovascular treatment of pseudo-aneurysm occurring after embolization of traumatic carotid cavernous fistula with detachable balloons. Chin Med J (Engl) 2008;121(15):1487-1491

21. Fang C, Li MH, Zhang PL, Wang W, Tan HQ, Xu HW and Zhou B. Endovascular Treatment for Very Small Supraclinoid Aneurysms with Stent-Assisted Coiling Long-Term Follow-up in Six Cases. Interventional neuroradiology 2009; 15: 37-44

22. Xie J, Li MH, Tan HQ, Zhu YQ, Li YD, Fan CH, Hu DJ, Qiao RH. Establishment of an Experimental Intracranial Internal Carotid Artery Model and the Application in Covered-Stent Navigability Testing. AJNR Am J Neuroradiol. 2009(5):1041-1045

23. Li MH, Cheng YS, Li YD, Fang C,Chen SW, Wang W, Hu DJ, Xu HW. Large-Cohort comparison between three-dimensional time-of-flight magnetic resonance and rotational digital subtraction angiographies in intracranial aneurysm detection. Stroke 2009 40(9):3127-3129

24. Zhu YQ，Cheng YS，Li MH，Zhang HX，Zhao JG，Wang YL. Comparison of Tissue Reaction with Three Different Endografts Used for Exclusion of Carotid Artery Aneurysm in a Dog Model. J Vasc Interv Radiol. 2009;20(6): 791-798

25. Li MH, Li YD, Tan HQ, Luo QY, Cheng YS. Treatment of Distal Internal Carotid Artery Aneurysm with the Willis Covered Stent: A Prospective Pilot Study. Radiology 2009; 253(2):470-477

26. Zhu YQ, Li MH, Fang C, Fang C, Wang W, Tan HQ, Cheng YS. Combined Endovascular and Vascular Surgical Therapy of Blister-like Distal Internal Carotid Aneurysm in a Right-Sided Aortic Arch Patient. Vascular. 2010;18(6):363-366

27. Li YD, Li MH, Gao BL, Fang C, Cheng YS, Wang W, Li WB, Zhao JG, Zhang PL, Wang J, Li M. Endovascular treatment of recurrent intracranial aneurysms with re-coiling or covered stents. J Neurol Neurosurg Psychiatry. 2010 Jan;81(1):74-79

28. Li MH, Leng B, Li YD, Tan HQ, Wang W, Song DL, Tian YL. Comparative study of covered stent with coil embolization in the treatment of cranial internal carotid artery aneurysm: a nonrandomized prospective trial. Eur Radiol. 2010;20(11):2732-2739

29. Zhu YQ, Li MH, Xie J, Tan HQ, Cheng YS, Wang JB. Treatment of carotid siphon aneurysms by use of the Willis stent graft: an angiographic and histopathological study. Eur Radiol. 2010 ;20(8):1974-1984.

30. Zhu YQ, Zhao JG, Li MH, Liu F, Wang JB, Cheng YS, Wang J, Li J. Retrograde transdorsal-to-plantar or transplantar-to-dorsal intraluminal re-entry following unsuccessful subintimal angioplasty for below-the-ankle arterial occlusion. J Endovasc Ther. 2010;17(6):712-721.

31. Zhu YQ, Li MH, Fang C, Tan HQ, Wang W, Zhang PL, Cheng YS, Wang JB, Ma LT. Application of the Willis covered stent in the treatment of aneurysm in the cisternal segment of the internal carotid artery: a pilot comparative study with midterm follow-up. J Endovasc Ther. 2010;17(1):55-65

32. Zhou B, Li MH, Wang W, Xu HW, Cheng YD, Wang J. Three- dimensional volume-rendering technique in the angiographic follow-up of intracranial aneurysms embolized with coils. J Neurosurg. 2010;112(3):674-680.

33. Fang C, Li MH, Zhu YQ, Tan HQ, Zhang PL, Xu HW, Wang W, Zhou B. The effectiveness and feasibility of endovascular coil embolization for very small cerebral aneurysms: mid- and long-term follow-up. Ann Vasc Surg. 2010 Apr;24(3):400-407

34. Zhu YQ, Gu BX, Li MH, Wang W, Cheng YS, Tan HQ, Wang JB, Zhang PL, Ma LT. Safety, feasibility, and mid-term follow-up of Willis stent graft placement in the treatment of symptomatic complicated intra- or extra-cranial aneurysms: a multicenter experience. Minim Invasive Ther Allied Technol. 2010 Dec;19(6):320-328

35. Shi WY, Li YD, Li MH, Gu BX, Chen SW, Wang W, Zhang BL, Li M. 3D rotational angiography with volume rendering: the utility in the detection of intracranial aneurysms. Neurol India 2010 Nov-Dec;58(6):908-913

36. Lu HT, Zhao JG, Li MH, Cheng YS, Wang J, Wang W. Subarachnoid contrast enhancement after endovascular packing of ruptured intracranial aneurysm with balloon assistance mimicking procedure-related intracerebral hemorrhage: case report and literature review. Neurosurg Q. 2010;20:189-193

37. Li MH, Li YD, Tan HQ, Wang W, Gu BX, Chen YC, Chen SW, Hu DJ. Contrast-free MRA at 3.0 T for the Detection of Intracranial Aneurysms. Neurology 2011;2011;77(7):667-676

38. Chen YC, Li MH, Li YH, Qiao RH. Analysis of correlation between the number of lenticulostriate arteries and hypertension based on high-resolution magnetic resonance angiography findings. AJNR 2011;32(10):1899-1903

39. Wang W, Li YD, Li MH,Tan HQ, Gu BX, Wang J, Zhang PL. Endovascular treatment of post-traumatic direct carotid-cavernous fistulas: A single-center experience. Journal of Clinical Neuroscience 2011;18(1):24-28

40. Xu HW, Yu SQ, Mei CL, Li MH. Screening for Intracranial Aneurysm in 355 Patients with Autosomal-Dominant Polycystic Kidney Disease. Stroke 2011;42:204-206

41. Tan HQ, Li MH, Li YD, Fang C, Wang JB, Wang W, Wang J, Zhang PL, Zhu YQ. Endovascular Reconstruction with the Willis Covered Stent for the Treatment of Large or Giant Intracranial Aneurysms. Cerebrovasc Dis 2011;31:154 -162

42. Tan HQ, Li MH, Zhang PL, Li YD, Wang JB, Zhu YQ, and Wang W. Reconstructive endovascular treatment of intracranial aneurysms with the Willis covered stent: medium-term clinical and angiographic follow-up. J Neurosurg 2011;114:1014-1020

43. Wang J, Zhu YQ, Li MH, Zhao JG, Tan HQ, Wang JB, Liu F, Cheng YS. Batroxobin plus Aspirin Reduces Restenosis after Angioplasty for Arterial Occlusive Disease in Diabetic Patients with Lower-limb Ischemia. J Vasc Interv Radiol 2011; 22(7):987-994

44. Chen YC, Li MH, Chen SW, Hu DJ, Qiao RH. Incidental Findings of Persistent Primitive Trigeminal Artery on 3-Dimensional Time-of-Flight Magnetic Resonance Angiography at 3.0 T: An Analysis of 25 Cases. J Neuroimaging 2011;21:152-158

45. Sun ZK, Li YD, Li MH, Chen SW, Tan HQ. Detection of infundibula using three-dimensional time-of-flight magnetic resonance angiography with volume rendering at 3.0 Tesla compared to digital subtraction angiography. Journal of Clinical Neuroscience 2011;18:504-508

46. Shi WY, Li YD, Li MH, Gu BX, Wang W, Zhang BL, Li M. Infundibular dilation: an anatomical variant or a pre-aneurysm? Advantages of assessment with three-dimensional rotational angiography. Surg Radiol Anat 2011;33:75–80

47. Fang C, Li MH, Zhu YQ, Tan HQ, Zhang PL, Wang J.Treatment of complex ruptured anterior communicating arterial aneurysms by endovascular coil embolisation of the anterior communicating artery. Br J Neurosurg. 2011; 25(5):591-5

48. Li YH, Li MH, Zhao JG, Wang W.  MRI-based ultrafast protocol thrombolysis with rt-PA for acute ischemia stroke in 12 hour time window. J Neuroimaging 2011 Oct;21(4):332-339

49. Wang W, Li MH, Li YD, Gu BX, Wang J, Zhang PL, and Li M. Treatment of Traumatic Internal Carotid Artery Pseudoaneurysms With the Willis Covered Stent: A Prospective Study. J Trauma 2011 ;70(4):816-822

50. Wu Q, Li MH. A comparison of 4D time-resolved MRA with keyhole and 3D time-of-flight MRA at 3.0 T for the evaluation of cerebral aneurysms. BMC Neurol. 2012;12:50

51. Lu HT, Zhao JG, Li MH, Li YD. Application of albumin prior to delayed thrombolysis reduces brain edema and blood brain barrier permeability in an embolic stroke model. Brain Res. 2012;1438:75-84

52. Sun ZK, Li M, Li MH, Li YD, Sun WP, Zhu YQ. Erdheim-chester Disease: Case report with Radiologic Characteristic and Biopsy Findings. Neurosurgery Quarterly 2012; 22(4):275-279

53. Sun ZK, Li M, Li MH, Li YD, Sun WP, Zhu YQ. Fenestrations accompanied by intracranial aneurysms assessed with magnetic resonance angiography. Neurology India 2012;60(1):45-49

54. Chen YC, Sun ZK, Li MH, Li YD, Wang W, Tan HQ, Gu BX, Chen SW. The clinical value of MRA at 3.0 T for the diagnosis and therapeutic planning of patients with subarachnoid haemorrhage. Eur Radiol. 2012;22(7):1404 -1412

55. Shi WY, Li MH, Yan L, Zhu YQ. Creation of Carotid Fusiform Aneurysm in a Canine Model: Comparison of the Surgical Venous-graft Model With the Model Induced by Porcine Elastase With or Without Balloon Assistance. Neurosurgery Quarterly. 2012;22(4):255-260

56. Li MH, Zhang JY, Pan JW, Lu ZG. Coronary total occlusion lesions: Linear intrathrombus enhancement at CT predicts better outcome of percutaneous coronary intervention. Radiology 2013;266(2):443-451

57. Li MH, Zhang JY, Pan JW, Lu ZG. Obstructive coronary artery disease: reverse attenuation gradient sign at CT indicates distal retrograde flow--a useful sign for differentiating chronic total occlusion from subtotal occlusion. Radiology 2013;266(3):766-772

58. Yan L, Shi WY, Wang D, Zhu YQ, Tan HQ, Li MH. Application of the Willis covered stent using the telescopic technique for the treatment of fusiform aneurysm in a canine model. Neurol India. 2013;61(1):45-50

59. Lai XB, Li MH, Tan HQ, Luo BY, Zhu YQ, Wang J, Li YD. Predictors of in-stent stenosis and occlusion after endovascular treatment of intracranial vascular disease with the Willis covered stent. J Clin Neurosci. 2013;20(1):122-127

60. Zhu YQ, Li MH, Lin F, Song DL, Tan HQ, Gu BX, Zhang HQ, Leng B, Zhang PL. Frequency and predictors of endoleaks and long-term patency after covered stent placement for the treatment of intracranial aneurysms: a prospective, non-randomised multicentre experience. European Radiology 2013;23:287-297

61. Shi WY, Li YD, Li MH, Gu BX, Gu JP.Differential diagnosis of infundibular dilation versus a small aneurysm of the internal carotid artery: assessment by three-dimensional rotational angiography with volume rendering. Neurol Sci. 2013; 34(7):1065-70.

62. Lu HT, Tan HQ, Gu BX, Wu-Wang, Li MH. Risk factors for multiple intracranial aneurysms rupture: a retrospective study. Clin Neurol Neurosurg. 2013; 115(6):690-4.

63. Yan L, Zhu YQ, Li MH, Tan HQ, Cheng YS.Geometric, hemodynamic, and pathological study of a distal internal carotid artery aneurysm model in dogs. Stroke. 2013; 44(10):2926-9.

64. Li MH , Chen SW, Li YD, Chen YC, Cheng YS, Hu DJ, Tan HQ, Wu Q, Wang W, Sun ZK, Wei XE, Zhang JY, Qiao RH, Zong WH, Zhang Y, Lou W, Chen ZY, Zhu Y, Peng DR, Ding SX, Xu XF, Hou XH, Jia WP）. Prevalence of Unruptured Cerebral Aneurysms in Chinese Adults Aged 35 to 75 Years: A Cross-sectional Study. Ann Intern Med. 2013 ;159(8):514-21

65. Li MH, Zhang JY, Pan JW, Lu ZG. Coronary Stenosis: Morphologic Index Characterized by Using CT Angiography Correlates with Fractional Flow Reserve and Is Associated with Hemodynamic Status. Radiology, 2013; 269:713-721

66. Chen H, Li MH. Magnetic resonance angiography diagnosis of infundibula occurring at an unusual location: Source image should not be overlooked. Neurol India. 2013;61(6):697-8.

67. Le WJ, Zhu YQ,  Li MH, Yan L, Tan HQ, Xiao SM, Cheng YS. New method for retrospective study of hemodynamic changes before and after aneurysm formation in patients with ruptured or unruptured aneurysms. BMC Neurol. 2013 Nov 6;13:166.

68. Li H, Yan L, Li MH, Li YD, Tan HQ, Gu BX, Wang W. Evaluation of intracranial aneurysms with high-resolution MR angiography using single-artery highlighting technique: correlation with digital subtraction angiography. Radiol Med. 2013 Dec;118(8):1379-1387.

69. Zhu YQ, Li MH, Yan L, Tan HQ, Cheng YS. Arterial wall degeneration plus hemodynamic insult cause arterial wall remodeling and nascent aneurysm formation at specific sites in dogs. J Neuropathol Exp Neurol. 2014;73(9):808-19

70. Li MH, Li YD, Gu BX, Cheng YS, Wang W, Tan HQ, Chen YC. Accurate diagnosis of small cerebral aneurysms ≤5 mm in diameter with 3.0-T MR angiography. Radiology. 2014;271(2):553-60

71. Wan-Yin S, Ming-Hua L, Lei Y, Yue-Qi Z, Jian-Ping G. Application of dual Willis covered stents in the management of large fusiform carotid aneurysms in a canine model. Vascular. 2014;22(6):432-8

72. Wan-Yin S, Ming-Hua L, Bin-Xian G, Yong-Dong L, Hua-Qiao T. Azygous anterior cerebral artery and associated aneurysms: detection and identification using 3-dimensional time-of-flight magnetic resonance angiography. J Neuroimaging. 2014;24(1):18-22

73. Chen H, Li MH.A1 segment hypoplasia accompanied by AcomA aneurysms assessed with magnetic resonance angiography. Surg Radiol Anat. 2014;36(4):353-7

74. Li MH，Li YD. Unusual Exclusion Criteria. Ann Intern Med. 2014;160（5）：368-368，IF=17.810

75. Li MH, Zhang J, Zhang Q, Pan J, Lu Z, Wei M.Coronary stent occlusion: reverse attenuation gradient sign observed at computed tomography angiography improves diagnostic performance. European Radiology 2015; 25(2):568-574.

76. Li MH, Liu S, Zhang J, Lu Z, Wei M, Chun EJ, Lu B.Coronary competitive reverse flow: Imaging findings at CT angiography and correlation with invasive coronary angiography. Journal of Cardiovascular Tomography 2015; 9(3):202-208.

77. Zhou G, Su M, Zhu YQ, Li MH. Efficacy of Flow-Diverting Devices for Cerebral Aneurysms: A Systematic Review and Meta-analysis. World Neurosurgey 2016;85：252-262.

78. Zhou G, Zhu YQ, Su M, Gao KD, Li MH. Flow-Diverting Devices versus Coil Embolization for Intracranial Aneurysms: A Systematic Literature Review and Meta-analysis. World Neurosurgey 2016;88：640-645.

79. Zhou G, Yin Y, Li MH. Flow Diversion for Cerebral Aneurysms: A Promising Therapy Needs Full Evaluation. World Neurosurgey. 2016;91：626-627.

80. Wang W, Wang YL, Chen M, Chen L, Zhang J, Li YD, Li MH, Yuan GY. Magnesium alloy covered stent for treatment of a lateral aneurysm model in rabbit common carotid artery: An in vivo study. Sci Rep. 2016 Nov 21;6:37401.

81. Shi WY, Gu JP, Li MH, Yan L, He X.The predictors of endoleaks after endovascular repair of experimentally produced fusiform carotid aneurysm in canine. Minim Invasive. Ther Allied Technol. 2016;25(2):99-106.

82. Wang W, Li MH, Li YD, Gu BX, Lu HT. Reconstruction of the Internal Carotid Artery After Treatment of Complex Traumatic Direct Carotid-Cavernous Fistulas With the Willis Covered Stent: A Retrospective Study With Long-Term Follow-up. Neurosurgery. 2016 Dec;79(6):794-805.

83. Tian QH, He CJ, Wu CG, Li YD, Gu YF, Wang T, Xiao QP, Li MH. Comparison of Percutaneous Cementoplasty with and Without Interventional Internal Fixation for Impending Malignant Pathological Fracture of the Proximal Femur. CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY 2016;39（1）：81-89

84. Li MH, Zhu Y, Song H, Gu B, Lu H, Li Y, Tan H, Cheng Y. Subarachnoid Hemorrhage in Patients with Good Clinical Grade: Accuracy of 3.0-T MR Angiography for Detection and Characterization. Radiology. 2017 Jul;284(1):191-199

85. Zhou G, Su M, Yin YL, Li MH. Complications associated with the use of flow-diverting devices for cerebral aneurysms: a systematic review and meta-analysis. Neurosurg Focus. 2017 Jun;42(6):E17.

86. Zhou G, Zhu Y, Yin Y, Su M, Li MH. Association of wall shear stress with intracranial aneurysm rupture: systematic review and meta-analysis. Sci Rep. 2017 Jul 13;7(1):5331

87. Wei XE, Li MH, Qiao RH, Yu WB and Li YH. Feasibility of Noninvasive Diagnosis of Spinal Vascular Diseases Using Time-Resolved Angiography with Stochastic Trajectories. Frontiers in Neurology 2021, doi:10.3389/fneur.2021.759099

88. Zhu yq, Zhang HB, Zhang YR, Wu HY, Wei LM, Zhou G, Zhang YZ, Deng LF, Cheng YS, Li MH, Santos HA and Cui WG: Endovascular Metal Devices for the Treatment of Cerebrovascular Diseases. Advanced Materials 2018, doi:10.1002./adma.201805452

89. Zhu YQ, Tan HQ, Wu ZX, et al: Use of covered stents to treat complex cerebrovascular diseases: Expert consensus. Frontiers in Cardiovascular Medicine 2022, doi:10.3389/fcvm.2022.934496