Biography

• Professor, Chief physician, PH. D supervisor. He is the chief expert of Renji Hospital，School of Medicine, Shanghai Jiaotong University; director of Shanghai Key laboratory of Gynecological oncology, vice chairman of Society of Obstetrics & Gynecology Chinese medical association. He was selected as the Health Leading Talents of Shanghai in 2011.

• Dr. Di holds clinical expertise in diagnosis and treatment of gynecologic malignant tumor, and has long been engaged in clinical and basic research in this field, focusing on the comprehensive treatment of gynecological tumors, especially in metastasis and drug-resistance mechanism of ovarian cancer. He has also been in-depth exploration of the diagnosis and treatment of pregnancy complicated with systemic lupus erythematosus (SLE) and its risk assessment, as well as the immune cell molecular mechanism of SLE placenta pathological damage.

• Dr. Di has undertaken more than 40 research projects as the principal investigator including 7 Natural Science Foundation of China, 1 key program for international Science and Technology Cooperation Projects of China, has published more than 200 papers in international journals and domestic core journals as the corresponding author, has issued more than 30 monographs as the editor-in-chief or editorial board member.

Publications

1. Li W, Lu L, Lu J, Wang X, Yang C, Jin J, Wu L, Hong X, Li F, Cao D, Yang Y, Wu M, Su B, Cheng J, Yang X, Di W, Deng L. cGAS-STING-mediated DNA sensing maintains CD8+ T cell stemness and promotes antitumor T cell therapy. Sci Transl Med. 2020 Jun 24;12(549):eaay9013. doi: 10.1126/scitranslmed.aay9013. PMID: 32581136. IF 19.31

2. Yin X, Yang J, Zhang M, Wang X, Xu W, Price CH, Huang L, Liu W, Su H, Wang W, Chen H, Hou G, Walker M, Zhou Y, Shen Z, Liu J, Qian K, Di W. Serum Metabolic Fingerprints on Bowl-Shaped Submicroreactor Chip for Chemotherapy Monitoring. ACS Nano. 2022 Feb 22;16(2):2852-2865. doi: 10.1021/acsnano.1c09864. Epub 2022 Jan 31. PMID: 35099942; PMCID: PMC9007521. IF 18.0

3. Wang Y, Shu W, Lin S, Wu J, Jiang M, Li S, Liu C, Li R, Pei C, Ding Y, Wan J, Di W. Hollow Cobalt Oxide/Carbon Hybrids Aid Metabolic Encoding for Active Systemic Lupus Erythematosus during Pregnancy. Small. 2022 Mar;18(11):e2106412. doi: 10.1002/smll.202106412. Epub 2022 Jan 22. PMID: 35064740. IF 15.2

4. Zhang Y, Liu Z, Thackray BD, Bao Z, Yin X, Shi F, Wu J, Ye J, Di W. Intraoperative Raman-Guided Chemo-Photothermal Synergistic Therapy of Advanced Disseminated Ovarian Cancers. Small. 2018 Jul 4:e1801022. doi: 10.1002/smll.201801022. Epub ahead of print. PMID: 29974621. IF 15.2

5. Cheng L, Zhou S, Zhou S, Shi K, Cheng Y, Cai MC, Ye K, Lin L, Zhang Z, Jia C, Xiang H, Zang J, Zhang M, Yin X, Li Y, Di W, Zhuang G, Tan L. Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer. Cancer Res. 2022 Oct 4;82(19):3588-3602. doi: 10.1158/0008-5472.CAN-22-0222. PMID: 35857807. IF 13.3

6. Yin X, Jing Y, Cai MC, Ma P, Zhang Y, Xu C, Zhang M, Di W, Zhuang G. Clonality, Heterogeneity, and Evolution of Synchronous Bilateral Ovarian Cancer. Cancer Res. 2017 Dec 1;77(23):6551-6561. doi: 10.1158/0008-5472.CAN-17-1461. Epub 2017 Sep 28. PMID: 28972072. IF 13.3

7. Bao Z, Deng B, Zhang Y, Li X, Tan Z, Gu Z, Gu B, Shao Z, Di W, Ye J. Ratiometric Raman nanotags enable intraoperative detection of metastatic sentinel lymph node. Biomaterials. 2021 Sep;276:121070. doi: 10.1016/j.biomaterials.2021.121070. Epub 2021 Aug 13. PMID: 34418817. IF 12.5

8. Bao Z, Zhang Y, Tan Z, Yin X, Di W, Ye J. Gap-enhanced Raman tags for high-contrast sentinel lymph node imaging. Biomaterials. 2018 May;163:105-115. doi: 10.1016/j.biomaterials.2018.02.020. Epub 2018 Feb 10. PMID: 29455067. IF 12.5

9. Wang Y, Liu P, Duan Y, Yin X, Wang Q, Liu X, Wang X, Zhou J, Wang W, Qiu L, Di W. Specific cell targeting with APRPG conjugated PEG-PLGA nanoparticles for treating ovarian cancer. Biomaterials. 2014 Jan;35(3):983-92. doi: 10.1016/j.biomaterials.2013.09.062. Epub 2013 Oct 28. PMID: 24176193.  IF 12.5

10. Xu C, Liu W, Hu Y, Li W, Di W. Bioinspired tumor-homing nanoplatform for co-delivery of paclitaxel and siRNA-E7 to HPV-related cervical malignancies for synergistic therapy. Theranostics. 2020 Feb 10;10(7):3325-3339. doi: 10.7150/thno.41228. PMID: 32194871; PMCID: PMC7053183. IF 11.6