Tier 2 Professors

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ZHANG Yucai

Professor

Research area: Clinical trial study of pediatric sepsis and extracorporeal life support / renal replacement therapy

Email:zhangyc@shchildren.com.cn

Tel: 021-62474880

Biography

  • Prof. Zhang graduated and received a MD & Ph.D degree from Shanghai Medical University in 1995. Served as director of Department of Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine in 2008. Currently, Prof. Zhang is the vice president of the Child Critical Care Doctor Branch of the Chinese Medical Doctor Association. Focused on study in septic shock and acute respiratory distress syndrome (ARDS). Trying to conduct high-quality clinical research for the evidence-based evidence based on extracorporeal life support including extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). CRRT trial study evidence was included in 2020 International the guidelines for the“Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children”.

Publications

  • Feng S, Cui Y, Zhou Y, Shao L, Miao H, Dou J, Liu T, Wang C, Zhang Y*. Continuous renal replacement therapy attenuates polymorphonuclear myeloid derived suppressor cell expansion in pediatric severe sepsis. Front Immunol. 13:990522. doi: 10.3389/fimmu.2022.990522.

  • Miao H, Cui Y, Lu Y, Sun T, Dou J, Ren Y, Wang C, Zhang Y*. Serum vimentin predicts mortality in pediatric severe sepsis: A prospective observational study. Int J Infect Dis. 2022,121:141-147. doi: 10.1016/j.ijid.2022.05.018.

  • Xu C, Liu X, Cui Y, Huang X, Wang Y, Fan Y, Wu H, Li X, Guo B, Zhang J, Zhang Y*. Therapeutic Drug Monitoring of Polymyxin B During Continuous Renal Replacement Therapy in Two Pediatric Patients: Do Not Underestimate Extracorporeal Clearance. Front Pharmacol. 2022,13:822981. doi: 10.3389/fphar.2022.822981.

  • Liu Z, Wang X, Zhang Y, Wang C, Wang F, Shi J, Dou J, Shan Y, Sun T, Zhou Y*. Lung Ultrasound in Pediatric Acute Respiratory Distress Syndrome Received Extracorporeal Membrane Oxygenation: A Prospective Cohort Study. Front Pediatr. 2022, 10:798855. doi: 10.3389/fped.2022.798855.

  • Miao H, Shi J, Wang C, Lu G, Zhu X, Wang Y, Cui Y, Zhang Y*. Continuous Renal Replacement Therapy in Pediatric Severe Sepsis: A Propensity Score-Matched Prospective Multicenter Cohort Study in the PICU. Crit Care Med. 2019 ,47(10):e806-e813. doi: 10.1097/CCM.0000000000003901.

  • Miao H, Wang F, Xiong X, Wang C, Zhang Y*. Clinical Benefits of High-Volume Hemofiltration in Critically Ill Pediatric Patients with Severe Sepsis: A Retrospective Cohort Study. Blood Purif. 2018;45(1-3):18-27. doi: 10.1159/000481249.