Research Interests

• The goal of Prof. Jing Ye is to lead the study of telomeres in aging research and medical practice. During her early carrier as a researcher, Prof. Jing Ye identified a crucial role of the shelterin protein TRF2 during telomere replication. This was followed by unexpected results pointing to “non canonical” roles of the same protein in neuronal gene expression and function. These seminal discoveries contributed to the concept of tissue-specific signaling of telomere dysfunction. Her current work is devoted to understand how these pathways shape systemic aging. As a clinical doctor, Prof. Jing Ye makes a substantial effort to understand the molecular mechanism of organic aging and the early prevention of age-related diseases.She is also contributed to translating her results in the clinic, particularly by the development of innovative telomere assays to screen compounds preventing the installation of neurodegenerative and metabolic disorders in the aging population.