Biography

• Dr. Feng Xue is a transplant physician and the Pediatric Director of Liver Transplantation at Renji Hospital affiliated to Shanghai Jiao Tong University School of Medicine, with a primary focus in management of adult and pediatric liver transplantation and transplant immunity. Areas of clinical expertise include: Improving long-term outcomes for liver transplant recipients by immune monitoring and personalized immunosuppression. Management of post-LT complications, especially in pediatric liver transplant recipients.

• In addition to her clinical activities, Dr. Xue is active in researches including molecular mechanisms of drug-induced liver injury (DILI), EBV associated PTLD, improving vaccine outcomes for post-LT recipients under immunosuppression. She has also been active in education, having been served as the surgery teaching director for the department. In addition to her work with medical students, Dr. Xue has mentored many transplant surgery fellows, both domestic and overseas, and she has been active in international collaboration.

Publications

1. Xu D, Qu X, Tian Y, Jie Z, Xi Z, Xue F, Ma X, Zhu J, Xia Q. Macrophage Notch1 Inhibits TAK1 Function and RIPK3-Mediated Hepatocyte Necroptosis Through Activation of β-Catenin Signaling in Liver Ischemia and Reperfusion Injury. Cell Commun Signal. 2022 Sep 16;20(1):144. doi: 10.1186/s12964-022-00901-8.                IF: 7.525 Q2

2. Wu J, Xie F, Ji H, Zhang Y, Luo Y, Xia L, Lu T, He K, Sha M, Zheng Z, Yong J, Li X, Zhao D, Yang Y, Xia Q, Xue F. A Clinical-Radiomic Model for Predicting Indocyanine Green Retention Rate at 15 Min in Patients With Hepatocellular Carcinoma. Front Surg. 2022 Mar 24;9:857838.      国家科技部重大专项基金：No.2018ZX10723203-003-003

3. 通讯作者      IF: 2.562 Q2

4. 周艾炜，刘源，薛峰等。儿童肝移植免疫耐受的研究进展。《器官移植》述评

5. 国家自然科学基金（No.82000586; No.82170669）       核心期刊     通讯作者

6. Zhu Y, Zhang Z, Song J, Qian W, Gu X, Yang C, Shen N, Xue F, and Tang Y. SARS-CoV-2-encoded microRNAs inhibit host type I interferon pathway and mediate allelic differential expression of susceptible gene.  Frontiers in immunology 2021 December 23;12: 767726.                                    共同通讯作者  IF 8.786，Q1

7. Zheng JX, Zhou H, Yang TH, Liu JC, Qin T, Gu XQ, Wu J, Zhang Y, Wang HL, Tang YJ,  Xue F, Mao YM and Xia Q. Protective role of microRNA-31 in acetaminophen-induced hepatic necrotic cell death: a negative regulator of c-Jun N-terminal kinase (JNK) signaling pathway. Cell Mol Gastroenterol Hepatol 2021 Jul 23;S2352-345X(21)00156-9. 国自然基金No.81670602和81470847；国家科技部重大专项基金：No.2018ZX10723203-003-003

8. 通讯作者，   IF 8.797, Q1

9. Liu JC, Fei Y, Zhou T, Ji H, Wu J, Gu XQ, Luo Y, Zhu JJ, Feng MX, Wan P, Qiu BJ, Lu YF, Yang T, Deng PF, Zhou CP, Gong DC, Deng J, Xue F, Xia Q. Bile acids impair vaccine response in children with biliary atresia. Frontiers in immunology 2021 April;12:642546 仁济临床科研创新培育基金                    通讯作者，   IF 8.786, Q1

10. Gu XQ, Tang D, Tang YJ, Wan P, Qin T, Yang TH, Wu J, Ji H, Liu JC, Xue F, Xia Q.  Multiple microRNAs regulate tacrolimus metabolism through CYP3A5.  Pharmacol Res. 2021 Feb; 164:105382. doi: 10.1016/j.phrs.2020.105382. Epub 2020 Dec 18.

11. 国自然基金No.81670602        通讯作者，IF 10.334, Q1

12. Xue, F, Gao W, Qin T, et al. Immune Cell Function Assays in the Diagnosis of Infection in Pediatric Liver Transplantation: An open-labeled, two center prospective cohort study. Transl Pediatr 2021;10(2): 333-343.         国自然基金No.81670602，申康三年，IF 2.488

13. Tang J, Wang D, Shen Y, and Xue F. ATG16L2 overexpression is associated with a good prognosis in colorectal cancer. J Gastrointest Oncol 2021 https://dx.doi.org/10.21037/jgo-21-495.                  通讯作者， IF 2.892

14. Deng J, Chen Q, Chen Z, Liang K, Gao X, Wang X, Makota FV, Ong HS, Wan Y, Luo K, Gong D, Yu X, Camuglia S, Zeng Q, Zhou T, Xue F, He J, Wei Y, Xiao F, Ma J, Hill DL, Pierson W, Nguyen THO, Zhou H, Wang Y, Shen W, Sun L, Li Z, Xia Q, Qian K, Ye L, Rockman S, Linterman MA, Kedzierska K, Shen N, Lu L, Yu D. The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses. Nat Commun. 2021 May 24;12(1):3073. doi: 10.1038/s41467-021-23220-x. PMID: 34031386; PMCID: PMC8144586.

15. Wang T, Feng M, Luo C, Wan X, Pan C, Tang J, Xue F, Yin M, Lu D, Xia Q, Li B, Chen J. Successful Treatment of Pediatric Refractory Burkitt Lymphoma PTLD after Liver Transplantation using Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy. Cell Transplant. 2021 Jan-Dec;30:963689721996649. doi: 10.1177/0963689721996649. PMID: 33631963; PMCID: PMC7917414.

16. 贾丽燕，景懿磊，张千，吕晓颖，吴新瑞，马方晖，刘雯琼，薛峰*，朱燕波*. 新型冠状病毒肺炎爆发期间肝移植受者服药依从性与生命质量调查研究[J].肝脏.2021;26(6): 655-660. 国家科技部重大专项基金：No.2018ZX10723203-003-003   共同通讯作者

17. 吴新瑞，朱燕波*，薛峰*，景懿磊，马方晖，刘雯琼. 成年肝移植受者生命质量与自我领导力现状及关系探究. （《医学与社会》投稿中） 国家科技部重大专项基金：No.2018ZX10723203-003-003              共同通讯作者

18. 张家旭,封明轩,邱必军,等. 儿童肝移植受者疫苗接种的研究进展[J]. 中华器官移植杂志,2021,42(5):312-316. DOI:10.3760/ cma.j.cn421203-20201106-00379.

19. 陈弘扬,高敬阳,赵地,吴忌,陈金军,全显跃,李欣明,薛峰,周沐瑶,柏冰冰.LFSCA-UNet:基于空间与通道注意力机制的肝纤维化区域分割网络[J].中国图象图形学报,2021,26(09):2121-2134. 国家科技部重大专项基金：No.2018ZX10723203-003-003

20. Liu Y, Luo Y, Xia L, Qiu BJ, Zhou T, Feng MX, Xue F, Chen XS, Han LS, Zhang JJ, Xia Q.

21. Living-donor liver transplantation for children with tyrosinemia type I. J Dig Dis. 2020 Mar;21(3):189-194.

22. Qin T, Gu X, Jeong S, Song Y, Liu J, Zheng J, Xue F*, Xia Q. Impact of EBV infection and immune function assay for lymphoproliferative disorder in pediatric patients after liver transplantation: a single center experience. Hepatobiliary & Pancreatic Diseases International 2020;19: 3-11. 国自然基金No.81670602。            通讯作者，IF 2.428

23. Liu Y, Luo Y, Xia L, Qiu B, Zhou T, Feng M, Xue F, Chen X, Han L, Zhang J, Xia Q. The Effects of Liver Transplantation in Children With Niemann-Pick Disease Type B. Liver Transpl. 2019 Aug;25(8):1233-1240.

24. Zheng JX, Tang YJ, Yang TH, Qin T, Liu JC, Gu XQ, Xue F, and Xia Q. The long non-coding RNAs exert regulatory roles in acetaminophen induced liver injury. Journal of Digestive Diseases 2019;20: 308-317.     国自然基金No.81670602和81470847     通讯作者 IF: 1.82

25. 秦天* 顾向前 郑建新刘金川 唐元家 薛峰# 夏强#。儿童活体肝移植术后药物代谢差异相关miRNA及IncRNA的高通量测序分析。国自然基金No.8167060，中华器官移植杂志，2019,40.                                                通讯作者

26. 万平,陆晔峰,邱必军,等. 亲属活体肝移植治疗儿童甲基丙二酸血症30例的临床分析[J]. 中华器官移植杂志,2019,40(11):683-686. DOI:10.3760/cma.j.issn.0254-1785.2019.11.008.

27. 万平,邱必军,封明轩,等. 儿童肝移植术后微小病毒B19感染相关性贫血二例[J]. 中华器官移植杂志,2019,40(7):410-413. DOI:10.3760/cma.j.issn.0254-1785.2019.07.007.

28. Xue F, Shi SJ, Zhang ZZ, et al. Application of a novel liquid biopsy in patients with hepatocellular carcinoma undergoing liver transplantation. Oncol Lett. 2018 Apr;15(4):5481-5488. doi: 10.3892/ol.2018.8019. Epub 2018 Feb 9. PMID: 29552189; PMCID: PMC5840532.Oncol Lett 2018 Apr;15(4):5481-5488.                                     IF 2.311

29. Zhou T, Zhang JJ, Luo Y, Liu Y, Zhuang SY, Xue F, Han LZ, Xia Q. Clinical characteristics and outcome of liver transplantation for Alagille syndrome in children. J Dig Dis. 2017 Nov;18(11):658-662.

30. 刘源,夏强,张建军,薛峰,夏雷,罗毅,邱必军,封明轩,陈小松,韩龙志.亲体肝移植治疗新生儿肝内胆汁淤积型希特林缺乏症1例[J].实用器官移植电子杂志,2018,6(06):461-463.

31. 施少军，郑建新，秦天等。改良大鼠离体肝脏灌注模型在供肝冷保存中的应用研究。《胃肠病学》2017;22(9):517-22。                       通讯作者，核心期刊

32. 孟稼祥,万平,薛峰,罗毅,邱必军,封明轩,周韬,张建军,李敏,夏强.儿童肝移植术后病原菌感染的危险因素分析[J].肝胆外科杂志,2017,25(06):412-415.

33. Shi SJ and Xue F. Current Antioxidant Treatments In Organ Transplantation. Oxid Med and Cell Longev 2016;2016:8678510. doi: 10.1155/2016/8678510. Epub 2016 Jun 15.  Review.

34. 通讯作者       IF: 4.492

35. 施少军，薛峰。消化系统肿瘤外周血循环肿瘤细胞的研究进展。《胃肠病学》2016;21(2)107-110。                                通讯作者

36. Zhu W, Kuziora M, Creasy T, Lai Z, Morehouse C, Guo X, Sebastian Y, Shen D, Huang J, Dry JR, Xue F, Jiang L, Yao Y, Higgs BW. BubbleTree: an intuitive visualization to elucidate tumoral aneuploidy and clonality using next generation sequencing data. Nucleic Acids Res. 2016 Feb 29;44(4):e38. doi: 10.1093/nar/gkv1102. Epub 2015 Nov 17. PMID: 26578606; PMCID: PMC4770205.                                        IF: 9.112

37. Xue F, Higgs BW, Huang J, Morehouse C, Zhu W, Yao X, Brohawn P, Xiao Z, Sebastian Y, Liu Z, Xia Y, Shen D, Kuziora M, Dong Z, Han H, Gu Y, Gu J, Xia Q and Yao Y. HERC5 is a prognostic biomarker for post-liver transplant recurrent human hepatocellular carcinoma. J Transl Med. 2015 Dec 11;13:379-93.                            IF:4.23

38. Nie H, Li J, Yang XM, Cao QZ, Feng MX, Xue F, Wei L, Qin W, Gu J, Xia Q, Zhang ZG. Mineralocorticoid receptor suppresses cancer progression and the Warburg effect by modulating the miR-338-3p-PKLR axis in hepatocellular carcinoma.  Hepatology. 2015 Oct;62(4):1145-59.

39. Yang TH, Chen YK, Xue F, Han LZ, Shen CH, Zhou T, Luo Y,  Zhang JJ,  and Xia Q. Influence of CYP3A5 genotypes in tacrolimus dose requirement: age and its pharmacological interaction with ABCB1 genetics in Chinese pediatric liver transplantation. Int J Clin Pract 2015;69(Suppl.183):53-62.                              通讯作者  IF 2.54

40. Li H, Xia Q, Zeng B, Li ST, Liu H, Li Q, Li J, Yang SY, Dong XJ, Gao T, Munker S, Liu Y, Liebe R, Xue F, Li QG, Chen XS, Liu Q, Zeng H, Wang JY, Xie Q, Meng QH, Wang JF, Mertens PR, Lammert F, Singer MV, Dooley S, Ebert MP, Qiu DK, Wang TL, Weng HL.

41. Submassive hepatic necrosis distinguishes HBV-associated acute on chronic liver failure from cirrhotic patients with acute decompensation. J  Hepatol. 2015 Jul;63(1):50-9.

42. Zhao D, Long XD, Lu TF, Wang T, Zhang WW, Liu YX, Cui XL, Dai HJ, Xue F, Xia Q. Metformin decreases IL-22 secretion to suppress tumor growth in an orthotopic mouse model of hepatocellular carcinoma. Int J Cancer. 2015 Jun 1;136(11):2556-65.

43. 陈奕宽，薛峰，沈丛欢等。婴幼儿肝移植供受体的CYP3A5基因多态性对他克莫司药动学的影响。《中华器官移植杂志》2015;36(1):1-6。                通讯作者

44. 刘焕荣，陆芸，张正国，王建，刘光伟，薛峰。地塞米松调节T细胞免疫应答保护小鼠急性炎性肝损伤的作用。《胃肠病学》2015;20(6)324-8。           通讯作者

45. Zhao Y, Xue F, Sun J, Guo S, Zhang H, Qiu B, Gu J, Wang W, Zhang Z, Tang N, Zhou X, Yu J and Xia Q. Genome-wide methylation profiling of different stages of HBV-related HCC development in plasma cell-free DNA reveals potential biomarkers for early detection and high-risk monitoring of HCC. Clin Epigenetics 2014;6:1-18.      共同第一     IF 6.22

46. Xue F, Han LZ, Chen YK, et al. CYP3A5 genotypes affect tacrolimus pharmacokinetics and infectious complications in Chinese pediatric liver transplant patients. Pediatr Transplant. 2014Mar;18(2):166-76.                                    IF 1.63

47. Fu Y, Feng MX, Yu J, Ma MZ, Liu XJ, Li J, Yang XM, Wang YH, Zhang YL, Ao JP, Xue F, Qin W, Gu J, Xia Q, Zhang ZG. DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling. Oncotarget 2014;5(16):6701-15.                   IF 6.627

48. Chen Y, Han L, Xue F, Shen C, Lu J, Yang T, Zhang J, and Xia Q. Personalized tacrolimus dose requirement by CYP3A5 but not ABCB1 or ACE genotyping in both recipient and donor after pediatric liver transplantation. PLoS One 2014; 9(10): e109464. doi: 10.1371/journal.pone.0109464. eCollection 2014              通讯作者  IF 3.534

49. 
    

50. Feng MX, Ma MZ, Fu Y, Li J, Wang T, Xue F, Zhang JJ, Qin WX, Gu JR, Zhang ZG, Xia Q. Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation. Mol Cancer. 2014;13(1):226.                            IF 5.397

51. Li J, Yang XM, Wang YH, Feng MX, Liu XJ, Zhang YL, Huang S, Wu Z, Xue F, Qin WX, Gu JR, Xia Q, Zhang ZG. Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling. J Hepatol 2014;60(6):1225-34.                                      IF 10.40

52. Liu H, Yang H, Chen X, Lu Y, Zhang Z, Wang J, Zhang M, Xue L, Xue F, Liu G. Cellular metabolism modulation in T lymphocyte immunity. Immunology. 2014 May 19. doi: 10.1111/imm.12321.                               共同通讯作者  IF 4.078

53. Li J, Yang XM, Wang YH, Feng MX, Liu XJ, Zhang YL, Huang S, Wu Z, Xue F, Qin WX, Gu JR, Xia Q, Zhang ZG. Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling. J Hepatol. 2014 Jun;60(6):1225-34.

54. 卢军，王树军，季萍，王颖，韩龙志，夏韵，薛峰。41例婴幼儿活体肝移植术后T细胞分布特征及其在术后感染监测中的意义。《现代免疫学》2014;34(3):203-209. 通讯作者

55. 杨太华，薛峰。钇９０动脉栓塞内放疗治疗肝细胞癌：生物学经验、当前挑战与临床展望。《肝脏》2014;19(12):968-74。（综述）                通讯作者，核心期刊

56. Long XD, Zhao D, Wang C, Huang XY, Yao JG, Ma Y, Wei ZH, Liu M, Zeng LX, Mo XQ, Zhang JJ, Xue  F, Zhai B, Xia Q. Genetic Polymorphisms in DNA Repair Genes XRCC4 and XRCC5 and Aflatoxin B1-related Hepatocellular Carcinoma. Epidemiology 2013;24(5):671-81.                                            IF 5.738

57. Long XD, Yao JG, Zeng Z, Ma Y, Huang XY, Wei ZH, Liu M, Zhang JJ, Xue F, Zhai B, Xia Q. Polymorphisms in the coding region of X-ray repair complementing group 4 and aflatoxin B1-related hepatocellular carcinoma. Hepatology 2013;58(1):171-81.         IF 12.003

58. Xue F, Li H, Zhang J, Lu J, Xia Y, and Xia Q. miR-31 regulates interleukin 2 and kinase suppressor of ras 2 during T cell activation. Genes Immun 2013;14(2): 127-31.   IF 3.685

59. Kawai K, Xue F, Takahara T, Kudo H, Yata Y, Zhang W, and Sugiyama T. Matrix metalloproteinase-9 contributes to the mobilization of bone marrow cells in the injured liver. Cell Transplant 2012;21: 453-64.                     共同第一     IF  4.422

60. Xu N, Shen C, Luo Y, Xia L, Xue F, Xia Q, Zhang J. Upregulated miR-130a increases drug resistance by regulating RUNX3 and Wnt signaling in cisplatin-treated HCC cell. Biochem Biophys Res Commun 2012;425(2):468-72.                       IF 2.406

61. Xu N, Zhang J, Shen C, Luo Y, Xia L, Xue F, Xia Q. Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. Biochem Biophys Res Commun 2012; 423(4):826-31.                       IF 2.406

62. Zhu JJ, Xia Q, Zhang JJ, Xue F, Chen XS, Li QG, Xu N. Living donor liver transplantation in 43 children with biliary atresia: a single-center experience from the mainland of China. Hepatobiliary Pancreat Dis Int 2012;11(3):250-5.

63. Zhou T, Xue F, Han LZ, Xi ZF, Li QG, Xu N, Zhang JJ, and Xia Q. Invasive Fungal Infection after Liver Transplantation: Risk Factors and Significance of Immune Cell Function Monitoring. J Dig Dis 2011; 12:467-475.                通讯作者      IF 1.853

64. 薛峰 邱德凯。肝移植的内科指征及临床进展。《胃肠病学》2011;16(12):705-711。

65. 邓维 刘蕾 薛峰 韩龙志 奚志峰 张建军 夏强。肝移植早期他克莫司的药动学特征及干扰因素分析。《中华器官移植杂志》2011，32(12)：730-734。         通讯作者

66. 夏强，邱必军，薛峰。影响肝移植物长期存活的因素。《肝脏移植临床病理学》（军事医学科学出版社）2011，162-170。

67. Xue F, Zhang JJ, Xu LM, Zhang C, Xia Q. Protective Effects of HGF-MSP Chimer in a Rat Model of Liver Ischemia-reperfusion Injury. J Dig Dis 2010, 11:299-305.   IF 1.853

68. 薛峰 徐龙妹 张程 邓维 夏韵 张建军 夏强。重组人肝细胞生长因子激活因子(HGFA)质粒构建、表达及其功能研究。《胃肠病学》2010，15（1）：8-11。       通讯作者

69. Xue F, Zhang JJ, Han LZ, Li QG, Xu N, Zhou T, Xi ZF, Wu YM and Xia Q. Immune Cell Functional Assay in Monitoring of Liver Transplantation Recipients with Infection. Transplantation 2010;89(8):620-26.                           IF 3.789

70. Yata Y, Xue F, Takahara T, Kudo H, Hirano K, Yasumura S, Minemura M, Scanga AE, Sugiyama T. Docetaxel inhibits progression of human hepatoma cell line in vitro and is effective in advanced hepatocellular carcinoma. Hepatol Res.2010 Mar 1;40(3):304-10.                                                 IF 1.857

71. 薛峰 张建军 李齐根 张明 宋玉 徐宁 周韬 邓维 王思岳 夏强。他克莫司缓释胶囊对肝移植术后稳定期患者的临床疗效分析。《中华移植杂志》 2009，3：19-23。

72. 张建军  薛峰  陈小松  韩龙志  周韬  王鑫  奚志峰  夏强。ImmuKnowTM细胞免疫功能测定在监控肝移植术后感染中的应用。《中华器官移植杂志》 2009，30：284-286。

73. Xue F, Takahara T, Yata Y, Xia Q, Nonome K, Shinno E, Kanayama M, Takahara S, and Sugiyama T. Blockade of Rho/ROCK Signaling Can Prevent Progression of Hepatocellular Carcinoma in Matrix Metalloproteinase-dependent Manner. Hepatol Res.2008 38:810-17.                                           IF 1.644

74. Tahahara T, Xue F, Mazzone M, Yata Y, Nonome K, Kanayama M, Kawai K, Pisacane AM, Takahara S, Li XK and Michieli P. Metron factor-1 prevent liver injury without promoting tumor growth and metastasis. Hepatology 2008;47(6):2010-25.                           IF11.355

75. Xue F, Zhang JJ, Qiu F, Zhang M, Chen XS, Li QG, HAN LZ, Xi ZF and Xia Q. A Rho signaling inhibitor, Y-27632, inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse model. Chin Med J (Engl) 2007;120:2304-7.                                              IF 0.571

76. Xue F, Isaka Y, Takahara T, Imamura R, Suzuki C, Ichimaru N, Michieli P, Takahara S. HGF-MSP chimera protects the kidneys from ischemia-reperfusion injury. Biochem Biophys Res Commun 2007;363:451-6.                                 IF 2.849

77. Kanayama M, Takahara T, Yata Y, Xue F, Shinno E, Nonome K, Kudo H, Kawai K, Kudo T, Tabuchi Y, Watanabe A, Sugiyama T. Hepatocyte Growth Factor Promotes Colonic Epithelial Regeneration via Akt Signaling. Am J Physiol Gastrointest Liver Physiol. 2007 293(1):G230-9.                                  IF 3.761

78. 吕良敬，陈顺乐，顾越英，沈南，鲍春德，王元，薛峰，叶萍，俞忡照。Rho60/SSA基因转染Hep-2细胞作为间接免疫荧光检测底物及其应用。《标记免疫分析与临床》 2006，1：31-34.

79. Nonome K, Li XK, Takahara T, Kitazawa Y, Funeshima N, Xue F, Kanayama M, Shinno E, Kuwae C, Saito S, Watanabe A, and Sugiyama T. Human umbilical cord blood-derived cells differentiate into hepatocyte-like cells in the Fas-mediated liver injury model. Am J Physiol 2005；289(6): G1091-9.                   IF  3.472

80. Minemura M, Shimizu Y, Hirano K, Nakayama Y, Tokimitsu Y, Xue F, Takahara T, Watanabe A and Sugiyama T. Functional analysis of transactivation by mutants of hepatitis B virus X gene in human Hepatocellular carcinoma. Oncol Rep 2005; 14(2):495-499.    IF 1.572

81. Takahara T, Nonome K, Xue F, Yata Y, Kanayama M, Li XK. Human umbilical cord blood cells differentiate into hepatocyte-like cells in Fas mediated liver injury of immune deficient mice. Hepatology 2004; 40(4):616A-616A Suppl.

82. Takahara T, Sugiyama K, Zhang LP, Ando O, Fujii M, Yaka Y, Xue F, Minemura M, Watanabe A. Cotreatment with interferon-and –reduces liver fibrosis in a rat model. Hepatol Res. 2004; 28(3):146-54.                                                                     IF 1.173

83. Xue F, Takahara T, Yata Y, Kuwabara Y, Shinno E, Nonome K, Minemura M, Takahara S, Li X, Yamoto E, Watanabe A. Hepatocyte growth factor gene therapy accelerates regeneration in cirrhotic mouse livers after hepatectomy. Gut 2003; 52(5): 694-700.               IF 6.323

84. Xue F, Takahara T, Nonome K, Yata Y, Shinno E, Watanabe A. Rho-kinase inhibitor suppresses tumor growth and intrahepatic metastases of hepatocellular carcinoma - In vitro and in vivo study. Hepatology 2003; 38(4):400A-400A Suppl.

85. Lu LJ, Chen SL, Gu YY, Shen N, Bao CD, Wang Y, Xue F, Ye P, Yu CZ. Transfection, overexpression and clinical application of human 60 kDa Ro/SSA autoantigens in Hep-2 cells. Chinese Medical Journal 2003；116:350-353.                                IF 0.571

86. Takahara T, Zhang LP, Xue F, Minemura M, Sato H, Watanabe A. Modulation of matrix metalloproteinase-9 in hepatic stellate cells by three-dimensional type I collagen: its activation and signaling pathway. Hepatol Res. 2003;26(4):318-26.                                     IF 1.991

87. Xue F, Takahara T, Yata Y, Minemura M, Morioka CY, Takahara S, Yamato E, Dono K, Watanabe A. Attenuated acute liver injury in mice by naked hepatocyte growth factor gene transfer into skeletal muscle with electroporation. Gut 2002; 50(4): 558-62.                                                                                 IF 5.883

88. Xue F, Takahara T, Yata Y, Minemura M, Kuwabara Y, Watanabe A. HGF gene therapy by electroporation can enhance functional capacities of cirrhotic liver following 70% partial hepatectomy. Hepatology 2001; 34(4):382A-382A Part 2 Suppl.

89. Yang CD, Shen N, Xue F. Cloning and expression of beta 2-glycoprotein 1 recognized by antiphospholipid antibodies and its clinical investigation. Chin.Med J (Engl) 1999; 112(1): 67-71.

90. 王元，沈南，薛峰，裴军，陈顺乐。抗磷脂抗体阳性红斑狼疮患者外周血T细胞受体基因表达初探。中国免疫学杂志 1999；10。

91. Yang CD, Chen SL, Shen N, Qi M, Xue F. Detection of anti-recombinant beta 2-glycoprotein 1 and anti-recombinant beta 2-glycoprotein 1 fifth-domain antibodies in sera from patients with systemic lupus erythematosus. Rheumatol Int 1998; 18(1): 5-10.

92. 薛峰，沈南，陆瑜，陈顺乐. 重组自身抗原U1RNP多肽的制备及其在风湿病诊断中的意义。中华医学杂志1997; 77(5): 340-43.

93. 沈南，薛峰，陆瑜，陈顺乐。自身核抗原U1RNP70kD多肽全长基因克隆及鉴定。1997; 1: 15-18.

94. 杨程德，陈顺乐，沈南，陆瑜，叶萍，薛峰。人b2-GPI第五功能区cDNA的分子克隆及重组表达。上海免疫学杂志 1997；4。

95. 杨程德，陈顺乐，沈南，裴军，薛峰，陆瑜。人b2GPI全长cDNA的分子克隆及重组质粒构建。上海免疫学杂志 1996；6。

96. 薛峰，陈顺乐. 自身核抗原U1RNP70KD的分子特性 中国免疫学杂志 1995; 11: 733-35..陆瑜，沈南，薛峰，陈顺乐。自身核抗原U1RNP70kD多肽分子中U1RNA结合功能区的cDNA分子克隆及其在大肠杆菌中的表达。上海免疫学杂志 1995; 15(4): 213-217.