College of Health Science and Technology

Xiangfan Liu

No 197, Ruijin Er Road, Ruijin Hospital, Shanghai.

Email: liuxiangfan1976@163.com

Tel: 13817153982

Research Interest:  Cancer Biology

Molecular Mechanism of Tumorigenesis & Tumor Molecular Biomarkers

EDUCATION

  • Sep 1994- Aug 1999     Bethune Medical University            Clinical Medicine   Bachelor

  • Sep 1999- Aug 2002     JiLin University Medical School        Internal Medicine   Master

  • Sep 2007-Aug 2010     Shanghai Jiaotong University Medical School   Clinical Diagnostics  PhD.

INTERNSHIP

  • Sep 2002 up to now     Department of Laboratory Medicine, Shanghai Jiaotong University Medical School

  • Mar2013-Apr 2014     UMASS Medical College, USA   Tumor Biology      Visiting Scholar & PostDoctor

Some Published Articles

  • Yanyan Hou , Jiafei Lin , Danyang Wang, Yingwei Zhang, Qiuli Liang , Ning Chen, Jiemin Wu, Weiqi Wu , Xiangfan Liu* , Peihua Ni *.The circular RNA circ_GRHPR promotes NSCLC cell proliferation and invasion via interactions with the RNA-binding protein PCBP2Clin Exp Pharmacol Physiol.. 2021 Aug; 48(8):1171-1181.

  • Jiafei Lin#, Yingwei Zhang#,Jiemin Wu, Li Li, Ning Chen, Peihua Ni, Lihua Song*, Xiangfan Liu* .Neuropilin 1(NPR1) is a novel tumor marker in hepatocellular carcinoma. Clinica Chemica Acta,2018 Oct;485:158-165

  • Chen J, Zhang H, Chen Y, Qiao G, Jiang W, Ni P*, Liu X*, Ma L*. miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT. Exp Cell Res, 2017;352(1):104-112.

  • Xiangfan Liu#, Huapeng Li,Mihir Rajukar,Qi Li,Jennifer L.Cotton,Jianhong Ou,Lihua J.Zhu,Hira L.Goel,Authur M.Mercurio,Joo-Seop Park,Roger J.Davis, Junhao Mao.Tead and AP1 Coordinate Transcription and Motility. Cell Reports, 2016 Feb, 14(5):1169-1180.

  • Xiangfan Liu#,Xiao Zhang, Ying Chen, Xiyi Yang, Lijun Ma ,Association of three common BARD1 variants with cancer susceptibility: a system review and meta-analysis ,Int J Clin Exp Med, 2015;8(1), 311-321.

  • Jiayi Wang#, Xiangfan Liu#,, Huacheng Wu, Peihua Ni, Zhidong Gu, Yongxia Qiao,Ning Chen, Fenyong Sun, and Qishi Fan.  CREB up-regulates long non-coding RNA, HULC  expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Research, 2010, 38:5366-5383.

  • ZHEN Zhao#, Xiangfan Liu#,Huacheng Wu, Shubiao Zou, Jiayi Wang, Peihua Ni, Xinhua Chen, Qishi Fan. Rab5a overexpression promoting ovarian cancer cell proliferation may be associated with APPL1-related epidermal growth factor signaling pathway. Cancer Science, 2010; 101:1454-1462.

  • Zhang X, Sun F, Qiao Y, Zheng W, Liu Y, Chen Y, Wu Q, Liu X, Zhu G, Chen Y, Yu Y, Pan Q, Wang J. TGCP2 Is Required for YAP-Dependent Transcription to Stimulate Live Malignancy. Cell Reports, 2017;21(5): 1227-1239.

  • Zhang X, Qiao Y, Wu Q, Chen Y, Zou S, Liu X, Zhu G, Zhao Y, Chen Y, Yu Y, Pan Q, Wang J, Sun F. The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis. Nature Communnication. 2017,5 ;8: 15280.

  • Rajurkar M, Dang K, Fernandez-Barrena MG, Liu X, Fernandez-Zapico ME, Lewis BC, Mao J. IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis. Cancer Res. 2017 Jan 15;77(2):320-329.