课题组长
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邹强 研究员
博士生导师
肿瘤免疫代谢课题组组长
上海交通大学医学院基础医学院副院长
国家自然科学基金优秀青年项目

 
受教育及工作经历
科研方向
科研项目
发表论文
小组成员
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  1. 1. Wu Z, Huang H, Han Q, Hu Z, Teng X-L, Ding R, Ye Y, Yu X*, Zhao R*, Wang Z*, Zou Q*. SENP7 senses oxidative stress to sustain metabolic fitness and antitumor functions of CD8+ T cells. Journal of Clinical Investigation. 2022, 132(7):e155224.

  2. 2. Wang F, Zhang Y, Yu X, Teng XL, Ding R, Hu Z, Wang A, Wang Z*, Ye Y*, Zou Q*. ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells. Journal of Clinical Investigation. 2021,131(19):e144318.

  3. 3. Hu Z#, Teng XL#, Zhang T, Yu X, Ding R, Yi J, Deng L*, Wang Z*, Zou Q*. SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function. Molecular Cell. 2021, Mar 4;81(5):940-952.e5.

  4. 4. Wang A#, Ding L#, Wu Z, Ding R, Teng X-L, Wang F, Hu Z, Chen L*, Yu X*, Zou Q*. ZFP91 is required for the maintenance of regulatory T cell homeostasis and function. Journal of Experimental Medicine, 2021, Feb 1;218(2):e20201217.

  5. 5. Zhou J, Zhang X, Hu J, Qu R, Yu Z, Xu H, Chen H, Yan L, Ding C, Zou Q, Ye Y, Wang Z, Flavell RA, Li HB. m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity. Science Advances, 2021 Jun 16;7(25):eabg0470.

  6. 6. Tong J, Wang X, Liu Y, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, Zou Q, Liu J, Zhou Y, Xia Q, Flavell RA, Zhu S, Li HB. Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation. Science Advances, 2021 Apr 28;7(18):eabd4742.

  7. 7. Jiang H, Yu Z, Ding N, Yang M, Zhang L, Fan X, Zhou Y, Zou Q, Hou J, Zheng J, Zhang L, Xu Y, Liu J. The role of AGK in thrombocytopoiesis and possible therapeutic strategies. Blood, 2020, Jul 2;136(1):119-129.

  8. 8. Hu Z#, Qu G#, Yu X#, Jiang H, Teng X-L, Ding L, Hu Q, Guo X, Zhou Y, Wang F, Li H-B, Chen L, Jiang J, Su B*, Liu J*, Zou Q*. Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells. Cell Metabolism, 2019, 30(2):290-302.e5.

  9. 9. Ouyang X, Han Y, Qu G, Li M, Wu N, Liu H, Arojo O, Sun H, Liu X, Liu D, Chen L, Zou Q*, Su B*. Metabolic regulation of T cell development by Sin1-mTORC2 is mediated by pyruvate kinase M2. Journal of Molecular Cell Biology, 2019, Feb 1; 11(2):93-106.

  10. 10. Yu X#, Teng X-L#, Wang F#, Zheng Y#, Qu G, Zhou Y, Hu Z, Wu Z, Chang Y, Chen L, Li H-B, Su B, Lu L*, Liu Z*, Sun S-C*, Zou Q*. Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome. Journal of Experimental Medicine, 2018, 215(9):2463-2476.

  11. 11. Yu X#, Lao Y, Teng X-L, Li S, Zhou Y, Wang F, Guo X, Deng S, Chang Y, Wu X, Liu Z, Chen L, Lu L, Cheng J, Li B, Su B, Jiang J, Li H-B*, Huang C*, Yi J*, Zou Q*. SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation. Nature Communications, 2018, 9:3157.

  12. 12. Xiao Y#, Zou Q#, Xie X#, Liu T, Li H, Jie Z, Jin J, Hu H, Manyam G, Zhang L, Cheng X, Wang H, Marie I, Levy D, Watowich S, and Sun S-C. The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity. Journal of Experimental Medicine, 2017, 214(5): 1493-1507.

 

                               

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