This core is composed of two parts. The first one is a collection of mouse stains commonly used for research in microbiology and immunology, including a variety of Cre mice, fluorescently engineered mice, and gene knock-out mice. This core maintains these strains and, upon request, provides mice to the laboratories at our institute. The other part of this core is a micromanipulation system, consisting of a OLYMPAS microinjection scope, PN-31 needle puller, M-F900 microforge, and EG-400 micropipette grinder. This system can be used for various microinjections, for instance embryo microinjection and microinjection of macromolecules, such as DNAs, RNAs, proteins, hormones, fluorescent antibodies, and dyes, into a cell or the nucleus of a cell. Additionally, this core has a KARL STORZ endoscope that can be used for observing and recording the colon of live mice. Priority usage of this core is given to researchers at our institute; outside users are welcome as well.

 1. Mouse common strain sharing

 2. In vivo endoscopy of mouse colon

 3. Microinjection of embryos or cells

Xiaodong Yang

Director

Email: xdyang@shsmu.edu.cn

Phone：021-63846590-776627

Wenguo Li

Operator

Email：guozi504805@163.com

Phone：021-63846590-776654