起源 该品系来源于2只雄性和7只雌性白化Swiss小鼠，这些Swiss小鼠来自于瑞士Centre Anticancereux Romand的de Coulon实验室的非近交品系，1926年Rockefeller研究所的Clara Lynch博士引入了这些小鼠，1948年费城癌症研究所用Rockefeller研究所培育出的“Swiss”小鼠培育出Hauschka Ha/ICR，并且由Edward Mirand博士引入Roswell Park Memorial Institute，命名为HaM/ICR。1973年引入中国。
特征与用途
◇解剖：体形较大，性情温顺。
◇免疫：对疾病的抵抗力强。
◇用途：主要用于药物安全性评价、药理学，毒理学、感染及免疫学实验等。
饲料 大小鼠繁殖料
来源于Taconic小鼠的生长曲线和生理指标
| Parameter |
Units |
ICR Males |
ICR Females |
| Serum Chemistry |
Avg ± S.D. |
|
|
| Calcium |
mg/dL |
10.6 ± 0.3 |
10.5 ± 0.4 |
| Phosphorous mg/dL |
11.1 ± 1.1 |
9.2 ± 0.9 |
|
| Glucose |
mg/dL |
181 ± 44 |
114 ± 18 |
| Creatinine |
mg/dL |
0.1 ± 0.1 |
0.1 ± 0.0 |
| BUN |
mg/dL |
25 ± 6 |
19 ± 1 |
| Total Bilirubin |
mg/dL |
0.2 ± 0.0 |
0.1 ± 0.0 |
| ALK |
U/L |
109 ± 15 |
145 ± 21 |
| ALT U/L |
U/L |
30 ± 9 |
39 ± 16 |
| Total Protein |
g/dL |
5.9 ± 0.3 |
6.3 ± 0.3 |
| Blood Counts |
| Erythron |
|
|
|
| Red Blood Cells |
X10^6/uL |
9.9525 ± 0.4818 |
9.5422 ± 0.6053 |
| Nucleated RBC |
X10^6/uL |
0 ± 0 |
0 ± 0 |
| Hemoglobin |
g/dL |
15.9 ± 0.5 |
16.0 ± 0.7 |
| Hematocrit |
% |
52.0 ± 2.6 |
50.6 ± 2.5 |
| MCV |
fL |
52 ± 2 |
53 ± 1 |
| MCH |
pG |
16.0 ± 0.3 |
16.8 ± 0.7 |
| MCHC |
% |
30.5 ± 0.7 |
31.6 ± 1.2 |
| Platelets |
|
|
|
| Platelets |
X10^3/uL |
1374 ± 257 |
1072 ± 162 |
| Leukogram |
|
|
|
| White Blood Cells |
x10^3/uL |
6.6625 ± 2.0486 |
5.7777 ± 1.8329 |
| Neutrophil |
x10^3/uL |
0.954 ± 0.705 |
0.779 ± 0.232 |
| Bands |
x10^3/uL |
0 ± 0 |
0 ± 0 |
| Lymphocyte |
x10^3/uL |
5.523 ± 1.710 |
4.792 ± 1.606 |
| Monocytes |
x10^3/uL |
0.156 ± 0.142 |
0.148 ± 0.087 |
| Eosinophil |
x10^3/uL |
0.030 ± 0.042 |
0.058 ± 0.062 |
| Basophils |
x10^3/uL |
0 ± 0 |
0 ± 0 |
| Others |
x10^3/uL |
0 ± 0 |
0 ± 0 |
| Organ Weights |
|
|
|
| Stomach |
g |
0.317 ± 0.045 |
0.319 ± 0.038 |
| Ileum |
g |
1.060 ± 0.211 |
0.915 ± 0.088 |
| Colon |
g |
0.278 ± 0.067 |
0.286 ± 0.054 |
| Lungs |
g |
0.308 ± 0.057 |
0.269 ± 0.044 |
| Heart |
g |
0.209 ± 0.042 |
0.160 ± 0.017 |
| Liver |
g |
1.636 ± 0.241 |
1.247 ± 0.091 |
| Spleen/Pancreas |
g |
0.293 ± 0.046 |
0.275 ± 0.039 |
| Kidney (L) |
g |
0.277 ± 0.060 |
0.183 ± 0.013 |
| Kidney (R) |
g |
0.289 ± 0.060 |
0.178 ± 0.018 |
| Testes (L) |
g |
0.114 ± 0.023 |
- |
| Testes (R) |
g |
0.115 ± 0.020 |
- |
| Ovary (L) |
g |
- |
0.019 ± 0.005 |
| Ovary (R) |
g |
- |
0.017 ± 0.009 |
| Urinalysis |
|
|
|
| Glucose |
mg/dL |
29.67 ± 3.70 |
23.08 ± 1.22 |
| Blood |
- |
Negative |
Negative |
| Ph |
- |
6.45 ± 0.28 |
6.30 ± 0.26 |
| Protein |
mg/dL |
Trace/30+ |
Trace |
| Specific Gravity |
- |
1.02 ± 0 |
1.02 ± 0.01 |
