Qiannan Tang-上海市免疫学研究所

Name:Qiannan Tang
Office Location:280 South Chongqing Road, Room 1001, West #5 Building, Shanghai, China 200025
Telephone:86-21-63846383
Email:qiannan.tang@sjtu.edu.cn

Education and work experience

2006-2010 BS, Shandong University

2010-2016 Ph.D, Institute of Biophysics, Chinese Academy of Sciences

2017-2020 Postdoctoral Scientist, MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford

2020-2022 Postdoctoral Scientist, Li Ka Shing Faculty of Medicine, The University of Hong Kong

2023-present Shanghai Jiao Tong University, Shanghai Institute of Immunology

Research Interests

1. The biological function of left-handed Z-NAs

The research in the laboratory focuses on the unconventional left-handed nucleic acid, namely Z-nucleic acids (Z-NAs). Viral infection leads to the formation of Z-NAs and subsequently trigger cell death, moreover, endogenous Z-NAs have the potential to activate innate immune responses and inflammation which result in autoimmune diseases such as AGS and IBD or the neurodegenerative diseases.

The scientific questions we aim to explore include:

1.1 The function of Z-NAs in anti-viral immunity;

1.2 The function of Z-NAs in homeostasis or diseases;

1.3 Development of therapeutics against multiple diseases by modulating Z-NAs.

2. Anti-tumor Immunity

Application of cutting-edge technology in stem cell research on tumor immunotherapy.