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Education
| 1978-1983 |
Bengbu Medical Collage |
B.S. |
| 1985-1988 |
Bengbu Medical Collage |
M.S. |
| 1991-1994 |
Shanghai Second Medical University（SSMU） |
Ph.D |
| 1997-1998 |
Joint diseases Laboratory, McGill University, Montreal, Canada |
Postdoctoral fellow |
| 2002-2003 |
Torry Pines Institute for molecular studies, San Diego, California, USA |
Visiting Scientist |
Career
| 1983-1985 |
Bengbu Medical Collage Teaching assistant |
| 1989-1991 |
Department of Microbiology and Immunology, Anhui Medical University, Hefei, Anhui Lecture |
| 1994-1995 |
Shanghai institute of Immunology, SSMU, Shanghai Lecture |
| 1996-2002 |
Shanghai institute of Immunology and SSMU, Shanghai Vice professor |
| 2002-present |
Shanghai institute of Immunology/Basic Medicine / Institute of Medical Principal Investigator, Faculty |
Research Interests
The research in my laboratory focuses on the role of extracellular matrix (ECM), such as Cyr61/CCN1, in pathogensis and development of auto-inflammatory and autoimmune diseses. We study the protein and genes alteration in the diseases. Our studies have revealed that Cyr61/CCN1 deeply involved in the inflammation and tissue damage in rheumatoid arthritis, psoriasis and Sjogren's syndrome by promoting tissue cells (such as synovial fibroblast-like cells, kerotinocyte) activation and proliferation, enhancing inflammatory cytokines production interation with immune cells.
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