Selected Publications
(1) Du, X.; Li, J.; Wang, X.; Wu, W.; Zhu, T.; Yan, H.; Wu, C.; Li, Y.; Gao, Y.; Yi, H.; Kassegne, K.; Li, X.; Niu, X.; Helmby, H.; Wassmer, S. C.; Ye, Y.; Sripa, B.; Chen, G.#; Qian, M.#;Wang, Z.#, A pathogenic CD8⁺ TRM–chemokine axis orchestrates liver fibrosis and provides circulating biomarkers during chronic Clonorchis sinensis infection. Nature communications 2026, 25.
(2) Chen, W.; Zeng, Y.; Zheng, J.; Wang, J.; Gu, W.; Li, M.; Cheng, Z.; Qian, J.; Zhang, X.; Kabali, E.; Lv, C.; Chen, Y.; Yang, G.; Zhou, N.; Tan, X.; Zhu, C.; Tun, H. M.; Mohsin, M.; Rahman, T.; Zhou, Z.; Xiao, Y.; Chen, H.; Shi, C.; Bergquist, R.; Ross Fitzgerald, J.; Chen, S.; Chang, Y.-F.; Wang, Z.; Zhou, X.; Guo, X.; Utzinger, J.; Song, J.; Zhu, Y., Evaluation of antimicrobial resistance governance across 193 countries to inform the 2026 Global Action Plan update. Nature Medicine 2026.
(3) Guo, X.; Lei, Y.; Xu, Y.; Du, X.; Lin, L.; Luo, Y.; Xi, Y.; Guo, Y.; Niu, X.#; Wang, Z.#; Chen, G.#, PRL2 negatively regulates FcepsilonRI mediated activation of mast cells. Cell Death & Disease 2025, 16 (1), 322.
(4) Du, X.; Ren, B.; Li, C.; Li, Q.; Kan, S.; Wang, X.; Bai, W.; Wu, C.; Kassegne, K.; Yan, H.; Niu, X.; Yan, M.; Xu, W.; Wassmer, S. C.; Wang, J.#; Chen, G.#; Wang, Z.#, PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury. Nature communications 2024, 15 (1), 881.
(5) Lei, Y.; Guo, X.; Luo, Y.; Niu, X.; Xi, Y.; Xiao, L.; He, D.; Bian, Y.; Zhang, Y.; Wang, L.; Peng, X.#;Wang, Z.#; Chen, G.#, Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis. Nature communications 2024, 15 (1), 113.
(6) Huang, Y.-L.; Zhang, K.-Y.; Sun, Y.-L.; Qian, M.-B.#;Wang, Z.#, The risk of hepatobiliary complications in Clonorchis and Opisthorchis infection: A systematic review and meta-analysis. Acta tropica 2024, 260, 107457.
(7) Li, Q.; Yue, T.; Du, X.; Tang, Z.; Cui, J.; Wang, W.; Xia, W.; Ren, B.; Kan, S.; Li, C.; Wu, C.; Niu, X.; Li, B.; Lin, K.; Luo, J.#; Chen, G.#;Wang, Z.#, HSC70 mediated autophagic degradation of oxidized PRL2 is responsible for osteoclastogenesis and inflammatory bone destruction. Cell death and differentiation 2023, 30 (3), 647-659.
(8) Kan, S.; Li, Q.; Li, H.-M.; Yao, Y.-H.; Du, X.-Y.; Wu, C.-Y.; Chen, G.-J.; Guo, X.-K.; Qian, M.-B.#; Wang, Z.-J.#, Clonorchis sinensis infection modulates key cytokines for essential immune response impacted by sex. PLoS neglected tropical diseases 2022, 16 (9), e0010726.
(9) Wu, C.; Du, X.; Tang, L.; Wu, J.; Zhao, W.; Guo, X.; Liu, D.; Hu, W.; Helmby, H.; Chen, G.#; Wang, Z.#, Schistosoma japonicum SjE16.7 Protein Promotes Tumor Development via the Receptor for Advanced Glycation End Products (RAGE). Frontiers in immunology 2020, 11, 1767.
(10) Yin, C.; Wu, C.; Du, X.; Fang, Y.; Pu, J.; Wu, J.; Tang, L.; Zhao, W.; Weng, Y.; Guo, X.; Chen, G.#; Wang, Z.#, PRL2 Controls Phagocyte Bactericidal Activity by Sensing and Regulating ROS. Frontiers in immunology 2018, 9, 2609.
(11) Fayngerts, S. A.*; Wang, Z.*; Zamani, A.; Sun, H.; Boggs, A. E.; Porturas, T. P.; Xie, W.; Lin, M.; Cathopoulis, T.; Goldsmith, J. R.; Vourekas, A.; Chen, Y. H., Direction of leukocyte polarization and migration by the phosphoinositide-transfer protein TIPE2. Nature immunology 2017, 18 (12), 1353-1360.
(12) Wu, C.; Chen, Q.; Fang, Y.; Wu, J.; Han, Y.; Wang, Y.; Yang, Y.; Chu, M.; Feng, Y.; Tan, L.; Guo, X.; Hu, W.; Wang, Z.#, Schistosoma japonicum egg specific protein SjE16.7 recruits neutrophils and induces inflammatory hepatic granuloma initiation. PLoS neglected tropical diseases 2014, 8 (2), e2703.
(13) Wang, Z.*; Fayngerts, S.*; Wang, P.; Sun, H.; Johnson, D. S.; Ruan, Q.; Guo, W.; Chen, Y. H., TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection. Proceedings of the National Academy of Sciences 2012, 109 (38), 15413-8.
(14) Wang, Z.*; Qiu, J.*; Guo, T. B.; Liu, A.; Wang, Y.; Li, Y.; Zhang, J. Z., Anti-inflammatory properties and regulatory mechanism of a novel derivative of artemisinin in experimental autoimmune encephalomyelitis. The Journal of Immunology 2007, 179 (9), 5958-65.
(15) Wang, Z.*; Hong, J.*; Sun, W.; Xu, G.; Li, N.; Chen, X.; Liu, A.; Xu, L.; Sun, B.; Zhang, J. Z., Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs. Journal of Clinical Investigation 2006, 116 (9), 2434-41.
