姓名：李相威

职称：研究员

学位/学历：医学博士

办公室地址：上海市黄浦区重庆南路280号老红楼122房间

办公电话：021-63846590-776408

邮箱：li.xiangwei@sjtu.edu.cn

教育经历

德国海德堡大学医学院 流行病学博士

工作经历

先后就职于中国医学科学院/北京协和医学院、海德堡大学医学院/德国癌症研究中心

科研方向/主要研究内容

与衰老、老龄人群健康有关的流行病学与分子流行病学研究，主要包括动物健康、环境健康与人群衰老、老龄人群健康的交互作用，基于多组学技术人群衰老有关的生物标志物研究，老龄人群健康规律研究等。

主要学术成果与影响力

- 第一作者/通讯作者在期刊Lancet Infectious Diseases，JAMA Oncology，Nature Communications，eClinicalMedicine，eBioMedicine等发表多篇SCI论文；

- JIMR Public Health and Surveillance副主编、PLOS Aging and Health等期刊编委；

- 国家留学基金委 “国家优秀自费留学生”、上海市海外高层次人才。

科研项目

国家自然科学基金面上项目、国家科技重大专项 “既往肺结核患者潜伏感染干预技术研究（2017ZX10201302-002）”  “肺结核和结核分枝杆菌潜伏感染的干预研究课题（2014ZX10003001）” 、“结核分枝杆菌感染的流行病学调查和队列研究（2013ZX10003004-002）”等。

发表论文（节选）

1. Zhang. H, Hao. D, Gong. Y, Xu. Y, Ding. C, An. T, et al. Associations of twelve DNA methylation algorithms of aging with mortality. hLife. 2025.(最后通讯)

2. Huo JH, Ding CY, Xu YQ, Zhang H, Gong YL, Hao DR, et al. Association between the healthy eating index and sarcopenia in Chinese elderly: a cross-sectional study. BMC Geriatrics. 2025; 25.(最后通讯)

3. Cui X, Sun SQ, Zhang H, Gong YL, Hao DR, Xu YQ, et al. Associations of DNA Methylation Algorithms of Aging With Cardiovascular Disease and Mortality Risk Among US Older Adults. Journal of the American Heart Association. 2025; 14.(最后通讯)

4. Cui X, Yi C, Zhang H, et al. DNA Methylation Algorithms of Aging and Incident Cardiovascular Disease: A Prospective Cohort Study. Journal of the American Heart Association 2025; 14: e045545.(最后通讯)

5. An TY, Zhang H, Xu YQ, Ding CY, Gong YL, Hao DR, et al. Associations of accelerated epigenetic aging with cancer and mortality risk in the USA. Geroscience. 2025.(最后通讯)

6. Li XW, Schöttker B, Holleczek B, Brenner H. Associations of DNA methylation algorithms of aging and cancer risk: Results from a prospective cohort study. Ebiomedicine. 2022; 81.(第一作者)

7. Li XW, Scho B, Holleczek B, Brenner H. Association of longitudinal repeated measurements of frailty index with mortality: Cohort study among. Eclinicalmedicine. 2022; 53.(第一作者)

8. Li XW, Delerue T, Schöttker B, Holleczek B, Grill E, Peters A, et al. Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Nat Commun. 2022; 13.(第一作者)

9. Li XW, Zhang Y, Gao X, Holleczek B, Schöttker B, Brenner H. Comparative validation of three DNA methylation algorithms of ageing and a frailty index in relation to mortality: results from the ESTHER cohort study. Ebiomedicine. 2021; 74.(第一作者)

10. Li X, Jansen L, Chang-Claude J, Hoffmeister M, Brenner H. Risk of Colorectal Cancer Associated With Lifetime Excess Weight. JAMA Oncol 2022; 8: 730–7.(第一作者)

小组成员

热忱欢迎您的加入（常年招收博士后）

Name: Xiangwei Li

Title: Professor

Degree: PhD

Office Address: Room 406, Old Red Building, No. 280 Chongqing South Road, Huangpu District, Shanghai, China

Office Phone: +86-21-63846590-776408

Email: li.xiangwei@sjtu.edu.cn

Education

PhD in Epidemiology

Faculty of Medicine, Heidelberg University, Germany

Professional Experience

Previously worked at the Chinese Academy of Medical Sciences / Peking Union Medical College, and the Faculty of Medicine, Heidelberg University / German Cancer Research Center (DKFZ).

Research Interests / Main Research Areas

Epidemiological and molecular epidemiological research related to aging and health in older populations. Main research areas include the interactions among animal health, environmental health, and human aging and health in older adults; identification of aging-related biomarkers using multi-omics technologies; and investigation of health patterns and determinants in aging populations.

Major Academic Achievements and Scholarly Impact

• Published multiple SCI papers as first or corresponding author in high-impact journals, including Lancet Infectious Diseases, JAMA Oncology, Nature Communications, eClinicalMedicine, and eBioMedicine;

• Deputy Editor of JIMR Public Health and Surveillance and editorial board member of PLOS Aging and Health and other journals;

• Recipient of the China Scholarship Council “National Outstanding Self-Financed Student Abroad” award and recognized as a Shanghai High-Level Overseas Talent.

Research Projects

Participated in and led multiple national-level research projects, including the National Natural Science Foundation of China (General Program) and National Science and Technology Major Projects, such as: “Intervention Strategies for Latent Tuberculosis Infection among Previously Treated Tuberculosis Patients” (2017ZX10201302-002); “Intervention Research on Tuberculosis and Latent Mycobacterium tuberculosis Infection” (2014ZX10003001); “Epidemiological Investigation and Cohort Study of Mycobacterium tuberculosis Infection” (2013ZX10003004-002), among others.

Selected Publications

1. Zhang H, Hao D, Gong Y, Xu Y, Ding C, An T, et al. Associations of twelve DNA methylation algorithms of aging with mortality. hLife. 2025. (Corresponding author)

2. Huo JH, Ding CY, Xu YQ, Zhang H, Gong YL, Hao DR, et al. Association between the healthy eating index and sarcopenia in Chinese elderly: a cross-sectional study. BMC Geriatrics. 2025;25. (Corresponding author)

3. Cui X, Sun SQ, Zhang H, Gong YL, Hao DR, Xu YQ, et al. Associations of DNA methylation algorithms of aging with cardiovascular disease and mortality risk among U.S. older adults. Journal of the American Heart Association. 2025;14. (Corresponding author)

4. Cui X, Yi C, Zhang H, et al. DNA methylation algorithms of aging and incident cardiovascular disease: a prospective cohort study. Journal of the American Heart Association. 2025;14:e045545. (Corresponding author)

5. An TY, Zhang H, Xu YQ, Ding CY, Gong YL, Hao DR, et al. Associations of accelerated epigenetic aging with cancer and mortality risk in the USA. Geroscience. 2025. (Corresponding author)

6. Li XW, Schöttker B, Holleczek B, Brenner H. Associations of DNA methylation algorithms of aging and cancer risk: results from a prospective cohort study. EBioMedicine. 2022;81.

7. Li XW, Schöttker B, Holleczek B, Brenner H. Association of longitudinal repeated measurements of frailty index with mortality: a cohort study. eClinicalMedicine. 2022;53.

8. Li XW, Delerue T, Schöttker B, Holleczek B, Grill E, Peters A, et al. Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Nature Communications. 2022;13.

9. Li XW, Zhang Y, Gao X, Holleczek B, Schöttker B, Brenner H. Comparative validation of three DNA methylation algorithms of ageing and a frailty index in relation to mortality: results from the ESTHER cohort study. EBioMedicine. 2021;74.

10. Li X, Jansen L, Chang-Claude J, Hoffmeister M, Brenner H. Risk of colorectal cancer associated with lifetime excess weight. JAMA Oncology. 2022;8:730–737.

Research Group

We warmly welcome applications from highly motivated researchers. Postdoctoral positions are available on a rolling basis.