姓名：张辉

职称：副研究员

联系方式：

办公室地址：上海市黄浦区重庆南路280号1号楼412室

办公室电话：021-63846590*776974

邮箱：zhanghui2939@sjtu.edu.cn

 

教育经历

2009.09-2014.07 济宁医学院 预防医学 学士

2014.09-2017.01 复旦大学 生物工程 硕士

2019.09-2022.06 复旦大学 遗传学 博士

 

工作经历

2018.06-2019.08  复旦大学生命科学学院 科研助理

2022.07-2024.06  复旦大学人类表型组研究院 博士后

2024.07-2024.12  上海交通大学医学院全球健康学院 助理研究员

2025.01-至今 上海交通大学医学院全球健康学院 副研究员

社会/学术任职和活动

Phenomics青年编委

 

科研方向/主要研究内容

衰老及老年病流行病学的研究。应用流行病学、生物信息学和统计学等方法，研究衰老及相关表型，如老年综合征、老年慢性病等。

 

科研项目

国家自然科学基金青年项目，基于纵向队列的老年人躯体恢复力的风险因素和生物标志物研究，2024.1-2026.12，在研，项目负责人

 

发表论文

1. Yu Yuexin#, Tang Yulong#, Li Xiangnan, Hu Zixin, Jin Li, Wang Jiucun, Jiang Shuai, Zhang Hui*, Liu Jing*. Association of physical activity, cardiorespiratory fitness, grip strength, and grip strength asymmetry with incident musculoskeletal disorders in 406,080 White adults. Journal of Sport and Health Science. 2025 April 8, 101040.

2. Zhang Hui*, Hao Meng, Hu Zixin, Jiang Shuai, Li Yi, Wang Xiaofeng, Li Xiangwei*. Social frailty and its association with cognitive trajectories in older adults: a prospective cohort study. Alzheimer’s Research & Therapy. 2025 Feb 19;17(1):50.

3. Zhang Hui, Hu Zixin, Wu Jingyi, Li Yi, Jiang Shuai, Jin Li, Wang Xiaofeng, Hao Meng*. Prevalence of cardiovascular-kidney-metabolic syndrome stages among middle-aged and older adults in China. JACC: Asia. 2025 Mar, 5 (3_Part_1) 393-395.

4. Hao Meng#, Zhang Hui#, Jiang Shuai, Hu Zixin, Jiang Xiaoyan, Wu Jingyi, Li Yi, Jin Li*, Wang Xiaofeng*. Metrics of Physiological Network Topology Are Novel Biomarkers to Capture Functional Disability and Health. Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 2024 Dec 11;80(1):glae268.

5. Hao Meng#, Jiang Shuai#, Tang Jingdong#, Li Xiangnan, Wang Shuming, Li Yi, Wu Jingyi, Hu Zixin*, Zhang Hui*. Ratio of red blood cell distribution width to albumin level and risk of mortality. JAMA Network Open. 2024 May 1;7(5):e2413213.

6. Zhang Hui#, Hu Zixin#, Jiang Shuai, Hao Meng, Li Yi, Liu Yining, Jiang Xiao-Yan, Jin Li*, Wang Xiaofeng*. Social frailty and the incidence of motoric cognitive risk syndrome in older adults. Alzheimer's & Dementia. 2024 Apr;20(4):2329-2339.

7. Pu Yanni#, Sun zhonghan#, Zhang Hui#, Huang Qingxia#, Wang Zhengdong, Mei Zhendong, Wang Peilu, Koing Mengmeng, Yang Wenjun, Lin Chenhao, Zhou Xiaofeng, Lin Shuchun, Huang Qiumin, Huang Lili, Sun Liang, Yuan Changzheng, Xu Qian, Tang Huiru*, Wang Xiaofeng*, Zheng Yan*. Gut microbial features and circulating metabolomic signatures of frailty in older adults. Nature Aging. 2024 Sep;4(9):1249-1262.

8. Xiao Wenze#, Wang Qi#, Liu Yining, Zhang Hui*, Zou Hejian*. Association of visceral adipose tissue with gout: Observational and Mendelian randomization analyses. Chinese Medical Journal (English). 2024 Oct 5;137(19):2351-2357.

9. Zhang Hui#, Jiang Shuai#, Hao Meng, Li Yi, Hu Zixin, Jiang Xiao-Yan, Jin Li*, Wang Xiaofeng*. Association of cardiometabolic multimorbidity with motoric cognitive risk syndrome in older adults. Alzheimer’s & Dementia (Amsterdam, Netherlands). 2023 Nov 5;15(4):e12491

10. Zhang Hui#, Hao Meng#, Li Yi, Hu Zixin, Liu Zuyun, Jiang Shuai, Jin Li, Wang Xiaofeng*. Assessment of Physical Resilience Using Residual Methods and Its Association with Adverse Outcomes in Older Adults. Innovation in Aging. 2023 Oct 13;7(9):igad118.

11. Hao Meng#, Zhang Hui#, Li Yi#, Hu X, Hu Zixin, Jiang Xiao-Yan, Wang Jiucun, Sun Xuehui, Liu Zuyun, Daniel Davis, Jin Li*, Wang Xiaofeng*. Using physiological system networks to elaborate resilience across frailty states. Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 2023 Oct 12: glad243.

12. He Fan#, Li Yi#, Hu Zixin*, Zhang Hui*. Association of domain-specific physical activity with depressive symptoms: A population-based study. European Psychiatry. 2022 Dec 12;66(1):e5.

13. Zhang Hui#, Hao Meng#, Hu Zixin, Li Yi, Hu Xiaoxi, Jiang Xiaoyan, Liu Zuyun, Sun Xuehui*, Wang Xiaofeng*. Causal Association of Cardiac Function by Magnetic Resonance Imaging with Frailty Index: A Mendelian Randomization Study. Phenomics. 2022 Sep 29;2(6):430-437.

14. Zhang Hui#, Hao Meng#, Hu Zixin#, Li Yi, Jiang Xiao-Yan, Wang Jiucun, Jin Li, Liu Zuyun, Wang Xiaofeng*, Sun Xuehui*. Association of immunity markers with risk of incident frailty: the Rugao Longitudinal Aging Study. Immunity & Ageing. 2022 Jan 3;19(1):1.

15. Hao Meng#, Zhang Hui#, Hu Zixin, Jiang Xiao-Yan, Song Qi, Wang Xi, Wang Jiucun, Liu Zuyun*, Wang Xiaofeng*, Li Yi*, Jin Li*. Phenotype correlations reveal the relationships of physiological systems underlying human ageing. Aging Cell. 2021 Dec;20(12):e13519.