基本信息：
姓名：陶永
职称：副研究员，主治医师，博士生导师
邮箱：taoyent@@foxmail.com
个人简介：
华中科技大学同济医学院耳鼻咽喉头颈外科博士，哈佛医学院博士后。研究方向是优化治疗载体和探索治疗新靶点，开展啮齿类和非人灵长类内耳基因治疗，推动耳聋基因治疗临床转化，以实现听觉障碍的精准治疗。研究成果发表于Nature，JACS, Nature Communications，STTT，Hearing Research等杂志。目前主持或结题国家自然基金项目两项、省部级课题四项，入选国家“优青”、上海市“东方学者”、“浦江人才”、上海市卫生计生委“优秀青年医师培养计划”、上海交通大学医学院“双百人”、“九龙奖”。
主要研究方向：
优化载体推动遗传性耳聋基因治疗；探索噪音性聋的机制及治疗靶点；基因调控促进耳蜗细胞再生；非人灵长类动物内耳治疗研究。
代表性论文：
1. Yong Tao*, Xiaoyi Liu* , Liu Yang*, Cenfeng Chu, Fangzhi Tan, Zehua Yu, Junzi Ke, Xiang Li, Xiaofei Zheng, Xingle Zhao, Jieyu Qi, Chao-Po Lin, Renjie Chai#, Guisheng Zhong#, and Hao Wu#. AAV-ie-K558R mediated cochlear gene therapy and hair cell regeneration. Signal Transduction Targeted Therapy. Signal Transduction Targeted Therapy.2022,7(1):109. IF:38.11.
2. Zhuoer Sun*, Zhenzhe Cheng*, Neng Gong, Zhen Xu, Chenxi Jin, Hao Wu, and Yong Tao#. Neural presbycusis at ultra-high frequency in aged common marmosets and rhesus monkeys. Aging.2021,27;13(9). IF:5.7
3. Baoyi Feng*, Chenxi Jin, Zhenzhe Cheng, Xingle Zhao, Zhuoer Sun, Xiaofei Zheng, Xiang Li, Tingting Dong, Yong Tao# , and Hao Wu#. Mitochondrial Dysfunction and Therapeutic Targets in Auditory Neuropathy. Neural Plasticity. Neural Plasticity.2020,2020:8843485. IF:3.1
4. Xingle Zhao*, Chenxi Jin*, Tingting Dong, Zhuoer Sun, Xiaofei Zheng, Baoyi Feng, Zhenzhe Cheng, Xiang Li, Yong Tao#, and Hao Wu#. Characterization of Promoters for Adeno-associated Virus Mediated Efficient Cas9 Activation in Adult Cas9 Knock-In Murine Cochleae. Hearing Research.2020,394:107999. IF:3.7
5. Wen Kang*, Xingle Zhao*, Zhuoer Sun, Tingting Dong, Chenxi Jin, Ling Tong, Weidong Zhu, Yong Tao#, and Hao Wu#. Adeno-associated virus vector enables safe and efficient Cas9 activation in neonatal and adult Cas9 knockin murine cochleae. Gene Therapy.2020,27(7-8):392-405. IF:4.2
6. Yong Tao*, Mingqian Huang, Yilai Shu, Adam Ruprecht, Hongyang Wang, Yong Tang,Luk H. Vandenberghe, Qiuju Wang, Guangping Gao, Wei-Jia Kong#, and Zheng-Yi Chen#. Delivery of Adeno-Associated Viral Vectors in Adult Mammalian Inner Ear Cell Subtypes without Auditory Dysfunction. Human Gene Therapy.2018,29(4);492-506. IF:4.2Wen Kang* , Zhuoer Sun , Xingle Zhao , Xueling Wang , Yong Tao#, and Hao Wu#. Gene editing based hearing impairment research and therapeutics. Neuroscience Letters.2019,709:134326. IF:3.2
7. Xue Gao*, Yong Tao*, Veronica Lamas, Mingqian Huang, Wei-Hsi Yeh ,Bifeng Pan, Yu-Juan Hu, Johnny H. Hu, David B. Thompson, Yilai Shu, Yamin Li, Hongyang Wang, Shiming Yang,Qiaobing Xu, Daniel B. Polley, M. Charles Liberman, Wei-Jia Kong, Jeffrey R. Holt, Zheng-Yi Chen#, and David R. Liu#. Treatment of autosomal dominant progressive hearing loss by in vivo delivery of genome editing agents. Nature.2018,553(7687):217-221. IF:69.5
8. Shu Y*, Tao Y*, Li W, Shen J, Wang Z#, and Chen ZY#. Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo. Neural Plasticity.2016,9409846. IF: 3.1
