流行病学与生物统计学系

黄亨烨/ 职称:实验师

学历学位:硕士 研究生

Email: huanghy1107@shsmu.edu.cn,huanghy1107@qq.com

个人简介

2010年参加工作,曾在国家卫生部数据中心、知名医药公司担任医学统计分析师及部门主管多年。为多家知名药企、三甲医院的高级咨询顾问,提供临床试验方案设计、统计分析与数据挖掘、Meta分析等咨询工作,有丰富的培训和实战经验。目前就职于上海交通大学医学院,现为公共卫生学院流行病学与生物统计学系教师。近五年发表SCI文章17篇,总影响因子超100分,平均6.2分,为中华系列医学杂志特约撰稿发表临床研究方法学论文多篇。评审临床研究项目100余项,负责多中心临床试验项目的设计与管理、主持开发EDC系统10余项,为国家科技部重点研发计划精准医学研究项目组主要成员,为交大协同创新团队成员。

承担教学工作

主讲研究生《高级卫生统计学》,本科生《卫生统计学》、《医学统计学》、《流行病学》、《科研数据管理与统计分析》等课程。

主要研究方向

统计建模、临床研究方法学、数据管理技术等。

主要研究成果

Zhou C, Shi Y, Chai P, Wu F, Xia W, He X, Shi Y,Huang H, Jia R, Fan X. Contemporary update of overall prognosis and nomogram to predict individualized survival for Chinese patients with eyelid sebaceous carcinoma. EBioMedicine. 2018 Oct;36:221-228.(*co-Corresponding author, IF=8.143)


Qian Y, Yu S, Shi Y,Huang H, Fan C. Risk Factors for the Occurrence and Progression of Posttraumatic Elbow Stiffness: A Case-Control Study of 688 Cases. Front Med (Lausanne). 2020 Dec 16;7:604056.(*co-Corresponding author, IF=5.019)


Li X,Huang H, Xu H, Shi Y, Qian Y, Zou J, Yi H, Guan J, Yin S. Excessive daytime sleepiness, metabolic syndrome, and obstructive sleep apnea: two independent large cross-sectional studies and one interventional study. Respir Res. 2019 Dec 4;20(1):276.(*co-first author, IF=5.631)


Wang F, Xiong X, Xu H,Huang H, Shi Y, Li X, Qian Y, Zou J, Yi H, Guan J, Yin S. The association between obstructive sleep apnea syndrome and metabolic syndrome: a confirmatory factor analysis. Sleep Breath. 2019 Sep;23(3):1011-1019.(*co-Corresponding author, IF=2.816)


Xu H, Zhao X, Shi Y, Li X, Qian Y, Zou J, Yi H,Huang H, Guan J, Yin S. Development and validation of a simple-to-use clinical nomogram for predicting obstructive sleep apnea. BMC Pulm Med. 2019 Jan 18;19(1):18.(*co-Corresponding author, IF=3.317)


Jing J, Yinchen S, Xia C, Jing W, Chong C, Xun X,Hengye H, Kun L. Pharmacogenomic study on anti-VEGF medicine in treatment of macular Neovascular diseases: a study protocol for a prospective observational study. BMC Ophthalmol. 2018 Jul 24;18(1):181.(*co-Corresponding author, IF=2.209)


Ji M, Genchev GZ,Huang H, Xu T, Lu H, Yu G. Evaluation Framework for Successful Artificial Intelligence-Enabled Clinical Decision Support Systems: Mixed Methods Study. J Med Internet Res. 2021 Jun 2;23(6):e25929. doi: 10.2196/25929. PMID: 34076581.


Shen L, Qiu L, Liu D, Wang L,Huang H, Ge H, Xiao Y, Liu Y, Jin J, Liu X, Wang DW, Peterson ED, He B, Zhou N. The Association of Low Molecular Weight Heparin Use and In-hospital Mortality Among Patients Hospitalized with COVID-19. Cardiovasc Drugs Ther. 2021 Jan 4:1–8.


Xu P, Guo R, You J, Cheng S, Li J, Zhong H, Sun C, Xu H,Huang H, Li B, Zhao W. Dynamic evaluation of the prognostic value of 18F-FDG PET/CT in extranodal NK/T-cell lymphoma, nasal type. Ann Hematol. 2021 Apr;100(4):1039-1047.


Shen R, Xu PP, Wang N, Yi HM, Dong L, Fu D, Huang JY,Huang HY, Janin A, Cheng S, Wang L, Zhao WL. Influence of oncogenic mutations and tumor microenvironment alterations on extranodal invasion in diffuse large B-cell lymphoma. Clin Transl Med. 2020 Nov;10(7):e221.


Guo R, Xu P, Cheng S, Lin M, Zhong H, Li W,Huang H, Ouyang B, Yi H, Chen J, Lin X, Shi K, Zhao W, Li B. Comparison of Nasopharyngeal MR, 18 F-FDG PET/CT, and 18 F-FDG PET/MR for Local Detection of Natural Killer/T-Cell Lymphoma, Nasal Type. Front Oncol. 2020 Oct 14;10:576409.


Zhong H, Chen J, Cheng S, Chen S, Shen R, Shi Q, Xu P,Huang H, Zhang M, Wang L, Wu D, Zhao W. Prognostic nomogram incorporating inflammatory cytokines for overall survival in patients with aggressive non-Hodgkin's lymphoma. EBioMedicine. 2019 Mar;41:167-174.


Chen C, Chen X,Huang H, Han C, Qu Y, Jin H, Niu T, Zhang Y, Liu K, Xu X. Elevated plasma and vitreous levels of leucine-rich-α2-glycoprotein are associated with diabetic retinopathy progression. Acta Ophthalmol. 2019 May;97(3):260-264.


Xu PP, Fu D, Li JY, Hu JD, Wang X, Zhou JF, Yu H, Zhao X,Huang YH, Jiang L, Liu F, Su LP, Chen ZW, Zeng QS, Chen JP, Fang MY, Ma J, Liu T, Song YP, Yu K, Li Y, Qiu LG, Chen XQ, Gu J, Yan JS, Hou M, Huang HY, Wang L, Cheng S, Shen Y, Xiong H, Chen SJ, Zhao WL. Anthracycline dose optimisation in patients with diffuse large B-cell lymphoma: a multicentre, phase 3, randomised, controlled trial. Lancet Haematol. 2019 Jun;6(6):e328-e337.


Liu K, Song Y, Xu G, Ye J, Wu Z, Liu X, Dong X, Zhang M, Xing Y, Zhu S, Chen X, Shen Y,Huang H, Yu L, Ke Z, Rosenfeld PJ, Kaiser PK, Ying G, Sun X, Xu X; PHOENIX Study Group. Conbercept for Treatment of Neovascular Age-related Macular Degeneration: Results of the Randomized Phase 3 PHOENIX Study. Am J Ophthalmol. 2019 Jan;197:156-167.

Xu PP, Xiong J, Cheng S, Zhao X, Wang CF, Cai G, Zhong HJ,Huang HY, Chen JY, Zhao WL. A Phase II Study of Methotrexate, Etoposide, Dexamethasone and Pegaspargase Sandwiched with Radiotherapy in the Treatment of Newly Diagnosed, Stage IE to IIE Extranodal Natural-Killer/T-Cell Lymphoma, Nasal-Type. EBioMedicine. 2017 Nov;25:41-49.


Xu H, Wang H, Guan J, Yi H, Qian Y, Zou J, Xia Y, Fu Y, Li X, Jiao X,Huang H, Dong P, Yu Z, Yang J, Xiang M, Li J, Chen Y, Wang P, Sun Y, Li Y, Zheng X, Jia W, Yin S. Effects of continuous positive airway pressure on neurocognitive architecture and function in patients with obstructive sleep apnoea: study protocol for a multicentre randomised controlled trial. BMJ Open. 2017 May 25;7(5):e014932.


黄亨烨,施悦,仇玉兰,等.国内临床试验方案常见问题与报告规范的探讨[J].中华医学科研管理杂志, 2018, 31(3):134-139.


黄亨烨,张硕,冯铁男,等.大学附属医院医师临床研究能力与培训需求分析[J].中华医学科研管理杂志, 2017, 30(8):238-244.


统计建模方法的理论研究及应用:倾向性得分匹配(PSM),逆概率加权(IPW),列线图(Nomogram),分类回归树(CART),结构方程模型(SEM),潜在分类和潜在剖面分析(LCA/LPA),混合因子模型(FFM),工具变量(IV),广义线性模型(GLM),神经网络模型(NN),诊断性研究(DS),时间序列分析(TSA),荟萃分析(Meta),LASSO回归等统计学方法/模型在医学科研中的应用。

获得荣誉称号

2020年获上海市高校青年教师教学竞赛二等奖