个人简介：

  上海交通大学公共卫生学院副研究员，上海市高层次人才。

       2021年毕业于中国科学院大学上海营养与健康研究所，获得医学博士学位，专业方向为免疫学；2021-2023年在上海交通大学医学院公共卫生学院从事博士后研究工作；2023.12-至今进入上海交通大学医学院公共卫生学院工作。

  从事精准营养与肝脏疾病防治研究。研究成果以第一/通讯作者的身份发表在Gut、Nature Communications、Cell Reports Medicine、Journal For Immunotherapy of cancer、Hypertension、Cardiovascular Diabetology、Clinical and Translational Medicine等国际一流杂志发表论文20余篇，其中ESI高被引论文2篇。

  受邀担任Military Medical Research（IF=22.9）科学编辑以及International Journal for Vitamin and Nutrition Research（IF=2.5）、AIMS Public Health（IF=3.3）和Food & Medicine Homolog期刊青年编委。

主持项目：

  国家自然科学基金青年项目

  中国博士后科学基金站中特别资助

  中国博士后科学基金面上资助。

奖励荣誉：

  上海市东方英才计划青年

  九龙医学优秀青年人才

  上海市启明星扬帆计划

  上海市超级博士后

研究领域：精准营养与肝脏疾病防治研究

1、以“风险因素识别-作用机制与生物靶点筛选-精准营养靶向策略开发”为核心思路，基于“人群（流行病学/临床标本）+基础（动物/细胞）”的研究策略，探究营养、环境等致病因素对肝脏稳态的调控作用，解析其在慢性肝病、肝癌发生发展及药物治疗应答中的作用及机制。

2、开展膳食营养素、膳食模式、运动、心理压力等主动健康生活方式的人群流行病学研究，明确其对慢性肝病及相关肿瘤的防控效应，并深入阐释其内在作用机制，为人群生活方式干预提供理论支撑。

代表性成果：

1. S. Yu, X. Shen, Y. Huang, L. Zou, C. Zhang, J. Cheng, Yang Y*, Mycotoxin Alternariol Exposure Promotes Endoplasmic Reticulum Stress-induced Hepatotoxicity to Exacerbate Chronic Liver Injury. Environmental Pollution, 2025, 127217. (通讯作者，IF=7.3)

2. Y. Yang, Pei T, Liu C, Cao M, Hu X, Yuan J, Chen F, Guo B, Hong Y, Liu J, Li B, Li X, Wang H*. Glutamine metabolic competition drives immunosuppressive reprogramming of intratumour GPR109A⁺ myeloid cells to promote liver cancer progression. Gut. 2025. (第一作者，ESI高被引论文，IF=26.2)

Highlighted as "The Q for immune evasion in HCC: ER stress in myeloid cells", Gut, 2025, https://doi.org/10.1136/gutjnl-2024-333249.

3. Yang Y, Pei T, Hu X, Lu Y, Huang Y, Wan T, Liu C, Chen F, Guo B, Hong Y, Ba Q, Li X, Wang H. Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell. Cell Reports Medicine. 2024 Sep 17;5(9):101718. (第一作者，IF=11.7)

4. Huang YQ, Wan TY, Hong YM, Wang XY, Jiang X, Yang Y, Gao H, Ji J, Wang L, Yang Y*, Li XG, Wang H. Impact of NAFLD and fibrosis on adverse cardiovascular events in patients with hypertension. Hypertension. 2025;82:1012–1023. (Featured Article, 共同通讯，IF=8.2)

5. Huang Y, Zhou Y, Xu Y, Wang X, Zhou Z, Wu K, Meng Q, Wang L, Yang Y, Gao H, Ji J, Jiang X, Yang Y*, Hao L, Wang H. Inflammatory markers link triglyceride-glucose index and obesity indicators with adverse cardiovascular events in patients with hypertension: insights from three cohorts. Cardiovascular Diabetology 24, 11 (2025). (共同通讯,ESI高被引论文，IF=10.6)

6. Y. Yang, M. Sun, W. Yao, F. Wang, X. Li, W. Wang, J. Li, Z. Gao, L. Qiu, R. You, C. Yang, Q. Ba, H. Wang, Compound kushen injection relieves tumor-associated macrophage-mediated immunosuppression through TNFR1 and sensitizes hepatocellular carcinoma to sorafenib. Journal for ImmunoTherapy of Cancer. 2020;8: e000317. (第一作者，IF=13.751)

7. Y. Yang, M. Sun, W. Li, C. Liu, Z. Jiang, P. Gu, J. Li, W. Wang, R. You, Q. Ba, X. Li, H. Wang. Rebalancing TGF-β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis. Clinical and Translational Medicine. 2021;11: e410. (第一作者，IF=11.492)

8. C. Liu, Y. Yang, C. Chen, L. Li, J. Li, X. Wang, Q. Chu, L. Qiu, Q. Ba, X. Li, H. Wang. Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice. Nature Communications, 2021, 12:5725. (共同第一作者，IF=17.694)

9. Y.Yang, Y. Lu, T. Pei, B. Guo, J. Li, H. Wang, Q. Ba. Compound kushen injection in cancer treatments: Efficacy, active ingredients, and mechanisms. Pharmacological Research - Modern Chinese Medicine. 2022; 3:100108. (第一作者)

10. M. Sun, P. Gu, Y. Yang, L. Yu, Z. Jiang, J. Li, Y. Chen, Q. Ba, H. Wang. Mesoporous silica nanoparticles inflame tumors to overcome anti-PD-1 resistance through TLR4-NFκB axis. Journal for ImmunoTherapy of Cancer. 2021; 9:e002508. (共同第一作者，IF=13.751)

11. H. Zhang, Q. Feng, L. Guo, M. Wang, Yang Y*, Y Zhao. Elucidation of the potential active ingredients and mechanism of Brassica rapa L. extract in alleviating ethanol-induced HepG2 cell injury based on network pharmacology. Food Bioscience 65 (2025) 106049. (共同通讯, IF=5.9)

12. Huang Y, Xu J, Yang Y, Wan T, Wang H*, Li X*. Association between Lifestyle Modification and All-Cause, Cardiovascular, and Premature Mortality in Individuals with Non-Alcoholic Fatty Liver Disease. Nutrients. 2024 Jun 28;16(13):2063. (共同第一作者，IF=5.0)

13. Bai PY, Chen SQ, Jia DL, Pan LH, Liu CB, Liu J, Luo W, Yang Y, Sun MY, Wan NF, Rong WW, Sun AJ, Ge JB. Environmental eustress improves postinfarction cardiac repair via enhancing cardiac macrophage survival. Science Advances. 2022 Apr 29;8(17): eabm3436.