食品安全与毒理学系

季晓媛/ 职称:副研究员/硕士生导师

学历学位:博士 研究生

Email: xyji@shsmu.edu.cn

个人简介:

2012年于中央民族大学获生物科学学士学位,2018年于苏州大学功能纳米与软物质研究院获化学博士学位。2018-2020年于上海交通大学医学院公共卫生学院从事博士后研究

2020-2022年受聘于上海交通大学医学院公共卫生学院任助理研究员。2022年起任上海交通大学医学院公共卫生学院副研究员。2018获上海市超级博士后激励计划资助2022年获上海交通大学医学院”九龙医学优秀青年人才奖“。2022年入选上海市卫健委卫生健康青年人才计划“。主持国自然青年基金项目上海市自然科学基金面上项目

多年来从事耐药性肿瘤防控新策略的发展和应用。针对肿瘤干细胞扩增和脂质代谢异常等肿瘤微环境特征,通过设计新型生物材料,发展精准靶向肿瘤基质细胞、抗原呈递细胞和免疫抑制性细胞的代谢干预技术,增强肿瘤对化疗和免疫疗法的敏感性,并有效地预防肿瘤的复发和转移。作为第一作者或通讯作者发表发表SCI论文15其中8篇影响因子大于25;平均影响因子19

代表性文章

#:共同第一作者;*:通讯作者;IF:影响因子)

1. Guo D#, Ji X#*, Xie H, Ma J, Xu C, Zhou Y, Chen N, Wang H*, Fan C*, Song H*. Targeted Reprogramming of Vitamin B3 Metabolism as a Nanotherapeutic Strategy towards Chemoresistant Cancers. Adv. Mater. 2023 June; 35:e2301257. (IF=29.4)

2. Xu C#, Ji X#*, Zhou Y, Cheng Y, Guo D, Li Q, Chen N*, Fan C*, Song H*. Slimming and Reinvigorating Tumor-Associated Dendritic Cells with Hierarchical Lipid Rewiring Nanoparticles. Adv. Mater. 2023 Apr; 35:e2211415. (IF=29.4)

3. Ma J#, Guo D#, Ji X#, Zhou Y, Liu C, Li Q, Zhang J*, Fan C*, Song H*.Composite Hydrogel for Spatiotemporal Lipid Intervention of Tumor Milieu. Adv. Mater. 2023 Apr 6; 35(14):e2211579. (IF=29.4)

4. Ji X, Li Q, Song H*, Fan C*. Protein-Mimicking Nanoparticles in Biosystems. Adv. Mater. 2022 Sep 15; 34(37):e2201562. (IF=29.4)

5. Ji X, Zhou Y, Li Q, Song H*, Fan C*. Protein-Mimicking Nanoparticles for a Cellular Regulation of Homeostasis. ACS Appl. Mater. Interfaces 2021 Jul 14;13(27):31331-31336. (IF=9.5)

6. Ji X, Guo D, Ma J, Yin M, Yu Y; Liu C; Zhou Y, Sun J, Li Q, Chen N*, Fan C*, Song H*. Epigenetic Remodeling Hydrogel Patches for Multidrug-resistant Triple-negative Breast Cancer. Adv. Mater. 2021, 33: 2100949. (IF=29.4)

7. Ji X, Peng F, Zhong Y, Su Y, Jiang X, Song C, Yang L, Chu B, Lee S*, He Y*. Highly fluorescent, photostable, and ultrasmall silicon drug nanocarriers for long-term tumor cell tracking and in-vivo cancer therapy. Adv. Mater. 2015, 27: 1029-1034. (IF=29.4)

8. Su Y#*, Ji X#, He Y*. Water-dispersible fluorescent silicon nanoparticles and their optical applications. Adv. Mater. 2016, 28: 10567-10574. (IF=29.4)

9. Guo D#, Ji X#, Peng F, Zhong Y, Chu B, Su Y*, He Y*. Photostable and biocompatible fluorescent silicon nanoparticles for imaging-guided co-delivery of siRNA and doxorubicin to drug-resistance cancer cells. Nano-Micro Letters 2019, 11:27. (IF=26.6)

10. Ji X#, Guo D#, Song B, Wu S, Chu B, Su Y, He Y*. Traditional chinese medicine molecules-assisted chemical synthesis of fluorescent anti-cancer silicon nanoparticles. Nano Res. 2018, 11: 5627-5641. (IF=9.9)

11. Ji X#, Wang C#, Tang M, Guo D, Peng F, Zhong Y, Song B, Su Y*, He Y*. Biocompatible protamine sulfate@silicon nanoparticles-based gene nanocarriers featuring strong and stable fluorescence. Nanoscale 2018, 10: 14455-14463. (IF=6.7)

12. Zhang L#, Ji X#, Su Y*, Zhai X, Xu H, Song B, Jiang A, Guo D, He Y*. Fluorescent silicon nanoparticles-based nanotheranostics agents for rapid diagnosis and treatment of bacteria-induced keratitis. Nano Res. 2021, 14: 52-58. (IF=9.9)