食品卫生与营养系

葛阳/ 职称:副研究员/硕士生导师​

学历学位:博士 研究生

Email: geyang19861026@icloud.com

个人简介

上海交通大学医学院公共卫生学院副研究员/硕士生导师。上海市委东方英才青年(原上海市青年拔尖)。中华预防医学会临床预防分会青年委员兼任副秘书长、中国医师协会临床精准医疗专委会青年委员。

主持省部级及以上科研项目 6 项,包括国家自然科学基金面上项目、青年科学基金项目、肿瘤系统医学全国重点实验室项目,上海市糖尿病重点实验室项目等,此外,还以课题骨干身份参与国家卫生健康委相关国家科技重大专项。近五年以第一 / 通讯作者(含共同)身份在高水平期刊发表 SCI 论文 18 篇,其中 JCR 一区论文 9 篇,最高影响因子25分。


主要研究方向

饮食及行为习惯影响特殊人群(慢性疾病包括糖尿病,消化系统癌症等)的分子生物机制及精准营养干预研究


代表性成果

1.Exposure of benzo[a]pyrene induces HCC exosome-circular RNA to activate lung fibroblasts and trigger organotropic metastasis, Cancer Commun (Lond), 2024 Co-corresponding author.

2.Benzo[a]pyrene stimulates miR-650 to promote hepatocellular carcinomas metastasis via target SOCS3/JAK/STAT3 cascades. J Mol Cell Biol ,2021 First author.

3.Exosomal CD44 cooperates with integrin α6β4 to support tumor metastasis via regulating tumor cell motility and target host cell activation. Engineering, 2020 Corresponding author

4.Hepatocellular Carcinoma-derived Exosomes in Organotropic Metastasis, Recurrence and Early Diagnosis Application. Cancer Lett 2019 First author

5.Transarterial chemoembolization versus percutaneous microwave coagulation therapy for recurrent unresectable intrahepatic cholangiocarcinoma: Development of a prognostic nomogram. Hepatobiliary & Pancreatic Diseases International.2020 First author

6.A single-center retrospective analysis of childhood hepatoblastoma in China. Gland Surgery 2020 Corresponding author

7.Cholangiocarcinoma Susceptible to Adjuvant Treatment After Resection: A Clinical Deep Learning Approach Frontiers in Oncology 2020 co-First author

8.Epigenetic regulation of UDP-Glucuronosyltransferase by microRNA-200a/-183: implications for responses to sorafenib treatment in patients with hepatocellular carcinoma. Cancer Letters 454 (2019) 14-25 First author