1.Lei, X.#, Chen, R., Wang, C., Shi, J., Zhao, Z., Li, W., Yan, B., Chillrud, S., Cai, J.*, & Kan, H*. (2019). Personal fine particulate matter constituents, increased systemic inflammation, and the role of DNA hypomethylation. Environmental science & technology, 53(16), 9837-9844.
2.Lei, X.#, Zhang, Y., Wang, Z., Lu, Z., Pan, C., Zhang, S., Chen Q, Yuan T, Zhang J, Gao Y*,& Tian, Y*. (2022). Effects of prenatal exposure to PM2.5 and its composition on cognitive and motor functions in children at 12 months of age: The Shanghai Birth Cohort Study. Environment International, 170, 107597.
3.Fan, G., Liu, Q., Fang, Q., Luo, F., Huang, X., Li, H., ... Lei, X.* & Song, L*. (2025). Prenatal exposure to PM2. 5 constituents and newborn leukocyte telomere length in a prospective study: Windows of susceptibility and modification by maternal folic acid supplementation. Journal of Hazardous Materials, 138747.
4.Fan, G.#, Lei, X.#, Liu, Q., Fang, Q., Luo, F., Huang, X., ... & Song, L*. (2025). Exposure to green space and leukocyte mitochondrial DNA copy number in children and adolescents. Environmental Research, 274, 121352.
5.Lei, X.#, Chen, R., Wang, C., Shi, J., Zhao, Z., Li, W., Bachwenkizi J , Ge W, Sun L, Li S, Cai J*, & Kan, H.* (2020). Necessity of personal sampling for exposure assessment on specific constituents of PM2. 5: Results of a panel study in Shanghai, China. Environment International, 141, 105786.
6.Lei, X.#, Ao, J., Li, J., Gao, Y., Zhang, J., & Tian, Y.* (2024). Maternal concentrations of environmental phenols during early pregnancy and behavioral problems in children aged 4 years from the Shanghai Birth Cohort. Science of The Total Environment, 933, 172985.
7.Zhang, S.#, Lei, X.*, Zhang, Y., Shi, R., Zhang, Q., Gao, Y., Tao Yuan , Li Jiong, & Tian, Y.* (2022). Prenatal exposure to per-and polyfluoroalkyl substances and childhood adiposity at 7 years of age. Chemosphere, 307, 136077.
8.Xia, Z.#, Lv, C., Zhang, Y., Shi, R., Lu, Q., Tian, Y., Lei, X.*, & Gao, Y.* (2023). Associations of exposure to bisphenol A and its substitutes with neurodevelopmental outcomes among infants at 12 months of age: A cross-sectional study. Chemosphere, 341, 139973.
9.Lei, X.#, Chen, R., Li, W., Cheng, Z., Wang, H., Chillrud, S., Yan, B., Ying Z, Cai J*, & Kan, H.* (2021). Personal exposure to fine particulate matter and blood pressure: Variations by particulate sources. Chemosphere, 280, 130602.
10.Lei, X.#, Muscat, J. E., Zhang, B., Sha, X., & Xiu, G.* (2018). Differentially DNA methylation changes induced in vitro by traffic-derived nanoparticulate matter. Toxicology, 395, 54-62.
website：https://orcid.org/0000-0003-0636-8677
https://www.shsmu.edu.cn/sph/info/1046/1551.htm
Biography
Personal Information
Xiaoning Lei, PhD
Associate Professor, Department of Environmental Health
School of Public Health, Shanghai Jiao Tong University School of Medicine
Office: +86-021-63846590-776522
Email: xiaoninglei@sjtu.edu.cn
Dr. Lei's research focuses on environmental epidemiology, employing interdisciplinary approaches from geography, chemistry, environmental science, and epidemiology. Her work investigates the adverse health effects of environmental factors such as air pollution, climate change, emerging pollutants, and lifestyle factors, with a particular emphasis on the psychological and neurodevelopmental risks among pregnant women and infants. She managed several research projects as the principle investigator, including the National Natural Science Foundation of China, the Science and Technology Commission of Shanghai Municipality, and the Shanghai Municipal Education Commission, etc. Additionally, she also participated in the National Key Research and Development Program of China and Key projects in the three-year plan of Shanghai municipal public health system as co-investigator. She has published over 50 papers in international journals, including Journal of Hazardous Materials, Environmental Science & Technology and Environment International. Her research has informed public health policy development and has been cited by authoritative sources such as The Lancet and the Chinese Center for Disease Control and Prevention (China CDC). Her work is also referenced in the "Recommendations for Controlling and Preventing the Acute Health Risks of PM2.5." Dr. Lei also serves as a reviewer for over ten international journals, including Science of the Total Environment, Environmental Pollution, and Environmental Research.
Education and Professional Experience
Dr. Xiaoning Lei is an associate professor in the Department of Environmental Health at the School of Public Health, Shanghai Jiao Tong University School of Medicine, China. She earned her Ph.D. from East China University of Science and Technology (2014-2018) and was a visiting scholar at Pennsylvania State University (2017-2018). She completed her postdoctoral research at Fudan University (2018-2020).
Research Interests
v Air pollution, climate change and public health
v Inner or extra-exposure to emerging pollutants and its effects on public health
v Perinatal lifestyle and maternal-infant health
Grants & Projects
v National Natural Science Foundation of China (NSFC), No.22206127, 2022-2025, PI.
v Project of the Integration of Industry, Education and Research of the Shanghai Municipal Education Commission, 2024-2025, PI.
v Program of Science and Technology Commission of Shanghai Municipality (21ZR1435800), 2021-2024, PI.
v Interdisciplinary Program of Shanghai Jiao Tong University (YG2019ZDA29), 2021-2023, PI.
v Young Faculty Startup Plan of Shanghai Jiao Tong University (21X010501089), 2020-2023, PI.
v China Postdoctoral Science Foundation (2019M661377), 2019-2020, PI.
v National Key Research and Development Program of China "Reproductive Health and Maternal and Child Health Protection", No. 2022YFC2702900, 2022-2025, co-investigator.
v Key projects in the three-year plan of Shanghai municipal public health system, No. GWVI-4, GWVI-11.1-41, 2023-2025, co-investigator.
v Program of Science and Technology Commission of Shanghai Municipality, No. 23ZR1436500, 2023-2026, co-investigator.
Selected Publications
1. Lei, X.#, Chen, R., Wang, C., Shi, J., Zhao, Z., Li, W., Yan, B., Chillrud, S., Cai, J.*, & Kan, H*. (2019). Personal fine particulate matter constituents, increased systemic inflammation, and the role of DNA hypomethylation. Environmental science & technology, 53(16), 9837-9844.
2. Lei, X.#, Zhang, Y., Wang, Z., Lu, Z., Pan, C., Zhang, S., Chen Q, Yuan T, Zhang J, Gao Y*,& Tian, Y*. (2022). Effects of prenatal exposure to PM2.5 and its composition on cognitive and motor functions in children at 12 months of age: The Shanghai Birth Cohort Study. Environment International, 170, 107597.
3. Fan, G., Liu, Q., Fang, Q., Luo, F., Huang, X., Li, H., ... Lei, X.* & Song, L*. (2025). Prenatal exposure to PM2. 5 constituents and newborn leukocyte telomere length in a prospective study: Windows of susceptibility and modification by maternal folic acid supplementation. Journal of Hazardous Materials, 138747.
4. Fan, G.#, Lei, X.#, Liu, Q., Fang, Q., Luo, F., Huang, X., ... & Song, L*. (2025). Exposure to green space and leukocyte mitochondrial DNA copy number in children and adolescents. Environmental Research, 274, 121352.
5. Lei, X.#, Chen, R., Wang, C., Shi, J., Zhao, Z., Li, W., Bachwenkizi J , Ge W, Sun L, Li S, Cai J*, & Kan, H.* (2020). Necessity of personal sampling for exposure assessment on specific constituents of PM2. 5: Results of a panel study in Shanghai, China. Environment International, 141, 105786.
6. Lei, X.#, Ao, J., Li, J., Gao, Y., Zhang, J., & Tian, Y.* (2024). Maternal concentrations of environmental phenols during early pregnancy and behavioral problems in children aged 4 years from the Shanghai Birth Cohort. Science of The Total Environment, 933, 172985.
7. Zhang, S.#, Lei, X.*, Zhang, Y., Shi, R., Zhang, Q., Gao, Y., Tao Yuan , Li Jiong, & Tian, Y.* (2022). Prenatal exposure to per-and polyfluoroalkyl substances and childhood adiposity at 7 years of age. Chemosphere, 307, 136077.
8. Xia, Z.#, Lv, C., Zhang, Y., Shi, R., Lu, Q., Tian, Y., Lei, X.,* & Gao, Y.* (2023). Associations of exposure to bisphenol A and its substitutes with neurodevelopmental outcomes among infants at 12 months of age: A cross-sectional study. Chemosphere, 341, 139973.
9. Lei, X.#, Chen, R., Li, W., Cheng, Z., Wang, H., Chillrud, S., Yan, B., Ying Z, Cai J*, & Kan, H.* (2021). Personal exposure to fine particulate matter and blood pressure: Variations by particulate sources. Chemosphere, 280, 130602.
10. Lei, X.#, Muscat, J. E., Zhang, B., Sha, X., & Xiu, G.* (2018). Differentially DNA methylation changes induced in vitro by traffic-derived nanoparticulate matter. Toxicology, 395, 54-62.
website：https://orcid.org/0000-0003-0636-8677
https://www.shsmu.edu.cn/sph/info/1046/1551.htm
