环境与健康系

雷晓宁/ 职称:副研究员/硕士生导师

学历学位:博士/研究生

Email: xiaoninglei@sjtu.edu.cn

个人简历

  雷晓宁

职称:副研究员/硕士生导师

学位/学历:博士/研究生

地址:上海市重庆南路280号西四楼717室

电话:021-63846590-776522

传真:021-64663944

Emailxiaoninglei@sjtu.edu.cn

雷晓宁,上海交通大学医学院-公共卫生学院-环境与健康系 副研究员,硕士生导师。美国宾夕法尼亚州立大学与华东理工大学联合培养博士,复旦大学公卫预防医学专业博士后。长期从事环境流行病学研究,整合空气污染和气候变化、新污染物、行为活动方式等因素,探究城市环境暴露组的健康效应及其机制,重点关注母婴易感人群。主持国家自然科学基金、上海市自然科学基金、上海市教委等教学科研项目9项;作为项目骨干,参加国家科技部重点专项及上海市加强公共卫生体系建设项目等。发表论文50余篇,包括Environ.Sci.Technol.、Environ.Int.、J.Hazard.Mater.等期刊。担任Eco-Environment & HealthJournal of Environmental Exposure Assessment青年编委,中国毒理学会发育毒理与发育源性疾病防控专业委员会会员,黄浦区科普专家库成员。为Sci.Total Environ.、Environ.Pollut.、Environ.Res.等国内外十余本杂志审稿。

欢迎对环境健康、地理流行病学、环境污染物暴露感兴趣的,有公共卫生、地理信息、环境科学、分析化学、计算机背景的同学加入。同时,课题组开放科研助理职位申请,欢迎具有相关背景的研究人员加入。



任教课程和指导学生项目

任教《现代环境卫生学》、《环境卫生》、《环境问题观察》、《塑料与健康》和《暴露科学》课程。

带队暑期海外游学项目,带教大学生创新创业训练计划,及暑期社会实践项目,并获优秀实践项目二等奖。



研究兴趣

空气污染、气候变化与人群健康

新污染物内外暴露与人群健康

围产期生活方式与母婴健康

科研项目

国家自然科学基金青年项目,2022-2025年,主持

上海市教委产学研项目,2024-2025年,主持

上海市自然科学基金面上项目,2021-2024年,主持

上海交通大学“HI 导师+AI 教师”课程变革计划,2025-2026年,主持

上海交通大学“交大之星”计划医工交叉研究基金,2021-2023年,主持

上海交通大学青年教师启动计划,2020-2023年,主持

中国博士后基金面上项目,2019-2020年,主持

环境监测与污染物控制兵团重点实验室开放课题,2019-2020年,主持

长三角环境气象预报预警中心气象与健康重点实验室开放课题,2018-2020年,主持

国家重点研发计划“生育健康及妇女儿童健康保障”重点专项,2022YFC2702900,2022-2025,参与

上海市科委上海市加强公共卫生体系建设三年行动计划项目,GWVI-4,GWVI-11.1-41,2023-2025,参与

上海市自然科学基金面上项目,23ZR1436500,2023-2026,参与


代表性研究成果

1.Lei, X.#, Chen, R., Wang, C., Shi, J., Zhao, Z., Li, W., Yan, B., Chillrud, S., Cai, J.*, & Kan, H*. (2019). Personal fine particulate matter constituents, increased systemic inflammation, and the role of DNA hypomethylation. Environmental science & technology, 53(16), 9837-9844.

2.Lei, X.#, Zhang, Y., Wang, Z., Lu, Z., Pan, C., Zhang, S., Chen Q, Yuan T, Zhang J, Gao Y*,& Tian, Y*. (2022). Effects of prenatal exposure to PM2.5 and its composition on cognitive and motor functions in children at 12 months of age: The Shanghai Birth Cohort Study. Environment International, 170, 107597.

3.Fan, G., Liu, Q., Fang, Q., Luo, F., Huang, X., Li, H., ... Lei, X.* & Song, L*. (2025). Prenatal exposure to PM2. 5 constituents and newborn leukocyte telomere length in a prospective study: Windows of susceptibility and modification by maternal folic acid supplementation. Journal of Hazardous Materials, 138747.

4.Fan, G.#, Lei, X.#, Liu, Q., Fang, Q., Luo, F., Huang, X., ... & Song, L*. (2025). Exposure to green space and leukocyte mitochondrial DNA copy number in children and adolescents. Environmental Research, 274, 121352.

5.Lei, X.#, Chen, R., Wang, C., Shi, J., Zhao, Z., Li, W., Bachwenkizi J , Ge W, Sun L, Li S, Cai J*, & Kan, H.* (2020). Necessity of personal sampling for exposure assessment on specific constituents of PM2. 5: Results of a panel study in Shanghai, China. Environment International, 141, 105786.

6.Lei, X.#, Ao, J., Li, J., Gao, Y., Zhang, J., & Tian, Y.* (2024). Maternal concentrations of environmental phenols during early pregnancy and behavioral problems in children aged 4 years from the Shanghai Birth Cohort. Science of The Total Environment, 933, 172985.

7.Zhang, S.#, Lei, X.*, Zhang, Y., Shi, R., Zhang, Q., Gao, Y., Tao Yuan , Li Jiong, & Tian, Y.* (2022). Prenatal exposure to per-and polyfluoroalkyl substances and childhood adiposity at 7 years of age. Chemosphere, 307, 136077.

8.Xia, Z.#, Lv, C., Zhang, Y., Shi, R., Lu, Q., Tian, Y., Lei, X.*, & Gao, Y.* (2023). Associations of exposure to bisphenol A and its substitutes with neurodevelopmental outcomes among infants at 12 months of age: A cross-sectional study. Chemosphere, 341, 139973.

9.Lei, X.#, Chen, R., Li, W., Cheng, Z., Wang, H., Chillrud, S., Yan, B., Ying Z, Cai J*, & Kan, H.* (2021). Personal exposure to fine particulate matter and blood pressure: Variations by particulate sources. Chemosphere, 280, 130602.

10.Lei, X.#, Muscat, J. E., Zhang, B., Sha, X., & Xiu, G.* (2018). Differentially DNA methylation changes induced in vitro by traffic-derived nanoparticulate matter. Toxicology, 395, 54-62.

website:https://orcid.org/0000-0003-0636-8677

https://www.shsmu.edu.cn/sph/info/1046/1551.htm


Biography

Personal Information

Xiaoning Lei, PhD

Associate Professor, Department of Environmental Health

School of Public Health, Shanghai Jiao Tong University School of Medicine

Office: +86-021-63846590-776522

Email: xiaoninglei@sjtu.edu.cn


Dr. Lei's research focuses on environmental epidemiology, employing interdisciplinary approaches from geography, chemistry, environmental science, and epidemiology. Her work investigates the adverse health effects of environmental factors such as air pollution, climate change, emerging pollutants, and lifestyle factors, with a particular emphasis on the psychological and neurodevelopmental risks among pregnant women and infants. She managed several research projects as the principle investigator, including the National Natural Science Foundation of China, the Science and Technology Commission of Shanghai Municipality, and the Shanghai Municipal Education Commission, etc. Additionally, she also participated in the National Key Research and Development Program of China and Key projects in the three-year plan of Shanghai municipal public health system as co-investigator. She has published over 50 papers in international journals, including Journal of Hazardous Materials, Environmental Science & Technology and Environment International. Her research has informed public health policy development and has been cited by authoritative sources such as The Lancet and the Chinese Center for Disease Control and Prevention (China CDC). Her work is also referenced in the "Recommendations for Controlling and Preventing the Acute Health Risks of PM2.5." Dr. Lei also serves as a reviewer for over ten international journals, including Science of the Total Environment, Environmental Pollution, and Environmental Research.

Education and Professional Experience

Dr. Xiaoning Lei is an associate professor in the Department of Environmental Health at the School of Public Health, Shanghai Jiao Tong University School of Medicine, China. She earned her Ph.D. from East China University of Science and Technology (2014-2018) and was a visiting scholar at Pennsylvania State University (2017-2018). She completed her postdoctoral research at Fudan University (2018-2020).

Research Interests

v Air pollution, climate change and public health

v Inner or extra-exposure to emerging pollutants and its effects on public health

v Perinatal lifestyle and maternal-infant health

Grants & Projects

v National Natural Science Foundation of China (NSFC), No.22206127, 2022-2025, PI.

v Project of the Integration of Industry, Education and Research of the Shanghai Municipal Education Commission, 2024-2025, PI.

v Program of Science and Technology Commission of Shanghai Municipality (21ZR1435800), 2021-2024, PI.

v Interdisciplinary Program of Shanghai Jiao Tong University (YG2019ZDA29), 2021-2023, PI.

v Young Faculty Startup Plan of Shanghai Jiao Tong University (21X010501089), 2020-2023, PI.

v China Postdoctoral Science Foundation (2019M661377), 2019-2020, PI.

v National Key Research and Development Program of China "Reproductive Health and Maternal and Child Health Protection", No. 2022YFC2702900, 2022-2025, co-investigator.

v Key projects in the three-year plan of Shanghai municipal public health system, No. GWVI-4, GWVI-11.1-41, 2023-2025, co-investigator.

v Program of Science and Technology Commission of Shanghai Municipality, No. 23ZR1436500, 2023-2026, co-investigator.

Selected Publications

1. Lei, X.#, Chen, R., Wang, C., Shi, J., Zhao, Z., Li, W., Yan, B., Chillrud, S., Cai, J.*, & Kan, H*. (2019). Personal fine particulate matter constituents, increased systemic inflammation, and the role of DNA hypomethylation. Environmental science & technology, 53(16), 9837-9844.

2. Lei, X.#, Zhang, Y., Wang, Z., Lu, Z., Pan, C., Zhang, S., Chen Q, Yuan T, Zhang J, Gao Y*,& Tian, Y*. (2022). Effects of prenatal exposure to PM2.5 and its composition on cognitive and motor functions in children at 12 months of age: The Shanghai Birth Cohort Study. Environment International, 170, 107597.

3. Fan, G., Liu, Q., Fang, Q., Luo, F., Huang, X., Li, H., ... Lei, X.* & Song, L*. (2025). Prenatal exposure to PM2. 5 constituents and newborn leukocyte telomere length in a prospective study: Windows of susceptibility and modification by maternal folic acid supplementation. Journal of Hazardous Materials, 138747.

4. Fan, G.#, Lei, X.#, Liu, Q., Fang, Q., Luo, F., Huang, X., ... & Song, L*. (2025). Exposure to green space and leukocyte mitochondrial DNA copy number in children and adolescents. Environmental Research, 274, 121352.

5. Lei, X.#, Chen, R., Wang, C., Shi, J., Zhao, Z., Li, W., Bachwenkizi J , Ge W, Sun L, Li S, Cai J*, & Kan, H.* (2020). Necessity of personal sampling for exposure assessment on specific constituents of PM2. 5: Results of a panel study in Shanghai, China. Environment International, 141, 105786.

6. Lei, X.#, Ao, J., Li, J., Gao, Y., Zhang, J., & Tian, Y.* (2024). Maternal concentrations of environmental phenols during early pregnancy and behavioral problems in children aged 4 years from the Shanghai Birth Cohort. Science of The Total Environment, 933, 172985.

7. Zhang, S.#, Lei, X.*, Zhang, Y., Shi, R., Zhang, Q., Gao, Y., Tao Yuan , Li Jiong, & Tian, Y.* (2022). Prenatal exposure to per-and polyfluoroalkyl substances and childhood adiposity at 7 years of age. Chemosphere, 307, 136077.

8. Xia, Z.#, Lv, C., Zhang, Y., Shi, R., Lu, Q., Tian, Y., Lei, X.,* & Gao, Y.* (2023). Associations of exposure to bisphenol A and its substitutes with neurodevelopmental outcomes among infants at 12 months of age: A cross-sectional study. Chemosphere, 341, 139973.

9. Lei, X.#, Chen, R., Li, W., Cheng, Z., Wang, H., Chillrud, S., Yan, B., Ying Z, Cai J*, & Kan, H.* (2021). Personal exposure to fine particulate matter and blood pressure: Variations by particulate sources. Chemosphere, 280, 130602.

10. Lei, X.#, Muscat, J. E., Zhang, B., Sha, X., & Xiu, G.* (2018). Differentially DNA methylation changes induced in vitro by traffic-derived nanoparticulate matter. Toxicology, 395, 54-62.

website:https://orcid.org/0000-0003-0636-8677

https://www.shsmu.edu.cn/sph/info/1046/1551.htm