The Leica RM2245 semi-automatic rotary paraffin microtome has a slicing thickness setting range of 10-60μm, a trimming thickness setting range of 10μm and 30μm, a horizontal sample feed range of 30mm, a vertical sample travel range of 70mm, a sample retraction of approximately 60μm, and precise positioning on the X/Y axis with stop positions every 2°. It also has a red 0 degree mark and other functions. It can be used to prepare various tissue and biological specimens, improve slicing quality, and increase reliability.