Contact Information

Office:

Email:Yongbo.Liu@shsmu.edu.cn

Office location

Yongbo Liu, Ph.D.

Associate Professor

  • Biography
  • Education & Experience
  • Publications
  • Lab Member
  • 1



  • 1



  • 1.Li HB, Muller M, Bahechar I, Kyrchanova O, Ohno K, Georgiev P, and Pirrotta V,Insulators, not Polycomb Response Elements, are required for long-range interactions between Polycomb targets in Drosophila,Mol. Cell. Biol,2011,31(4):616-25.[Link]

    2.Pirrotta V., and Li HB,A view of nuclear Polycomb bodies,Curr. Opin. Genet. Dev,2012,22(2):101-9.[Link]

    3.Schwartz YB, Linder-Basso D, Kharchenko PV, Tolstorukov MY, Kim M, Li HB, Gorchakov AA, Minoda A, Shanower G, Alekseyenko AA, Riddle NC, Jung YL, Gu T, Plachetka A, Elgin SC, Kuroda MI, Park PJ, Savitsky M, Karpen GH, Pirrotta V,Nature and function of insulator protein binding sites in the Drosophila genome,Genome Res,2012,22(11): 2188-98.[Link]

    4.Li HB, Ohno K, Gui H, and Pirrotta V,Insulators target active genes to transcription factories and Polycomb-repressed genes to PcG bodies,PLoS Genet,2013,9(4):e1003436.[Link]

    5.Li HB*, Jin C*, Chen Y*, Flavell RA,Inflammasome activation and metabolic disease progression,Cytokine Growth Factor Rev,2014,25(6):699-706.[Link]

    6.Zhu S*, Li HB*, Flavell RA,Resemble and Inhibit: When RLR Meets TGF-β,Mol Cell,2014,56(6):719-20.[Link]

    7.Cao G*, Li HB*, Yin Z, Flavell RA,Recent advances in dynamic m6A RNA modification,Open Biology,2016,6(4): 160003.[Link]

    8.Li HB,Chromosome Conformation Capture in Drosophila,Methods Mol. Biol.,2016,1480:207-12.[Link]

    9.Hu B*, Jin C*, Li HB*, Tong J, Ouyang X, Cetinbas NM, Zhu S, Strowig T, Lam FC, Zhao C, Henao-Mejia J, Yilmaz O, Fitzgerald KA, Eisenbarth SC, Elinav E, Flavell RA,The DNA Sensing Aim2 Inflammasome Controls Radiation Induced Cell death and Tissue Injury,Science,2016,354 (6313): 765-768.[Link]

    10.Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H, Li HB, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, Zhao Y, Jurado KA, Feng N, Shan L, Kluger Y, Lu J, Abraham C, Fikrig E, Greenberg HB, Flavell RA,Nlrp9b inflammasome recognizes and restricts rotavirus infection in intestinal epithelial cells,Nature,2017,546(7660): 667-670.[Link]

    11.Li HB*#, Tong J*, Zhu S*, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z#, Flavell RA#,m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway,Nature,2017,548(7667): 338-342.[Link]

    12.Tong J*, Cao G*, Zhang T*, Sefik E, Vesely M, Broughton J, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA#, Li HB#,m6A mRNA methylation sustains Treg suppressive functions,Cell Research,2018,28: 253–256.[Link]

    13.Yu X*, Lao Y*, Teng XL*, Li S, Zhou Y, Wang F, Guo X, Deng S, Chang Y, Wu X, Liu Z, Chen L, Lu LM, Cheng J, Li B, Su B, Jiang J, Li HB#, Huang C#, Yi J#, Zou Q#,SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation,Nat Commun.,2018,9(1):3157.[Link]

    14.Tong J, Flavell RA#, Li HB#,RNA m6A modification and its function in diseases,Frontiers of Medicine,2018,Aug;12(4):481-489.[Link]

    15.Yu X*, Teng XL*, Wang F*, Zheng Y*, Qu G, Zhou Y, Hu Z, Wu Z, Chang Y, Chen L, Li HB, Su B, Lu L#, Liu Z#, Sun SC#, Zou Q#,Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome,J Exp Med,2018,3;215(9):2463-2476.[Link]

    16.Liu Y, Li HB, Flavell RA,cGAS activation in phased droplets,Cell Research,2018,2018(0):1-2.[Link]

    17.Zhang X, Flavell RA#, Li HB#,hnRNPA2B1: a nuclear DNA sensor in antiviral immunity,Cell Research,2019,0:1–2.[Link]

    18.Wang J, Flavell RA#, Li HB#,Antiviral immunity: a link to bile acids.,Cell Research,2019,29(3): 177-178.[Link]

    19.Gao YM, Vasic R, Song YB, Teng R, Liu CY, Gbyli R, Biancon G, Nelakanti R, Lobben K, Kudo E, Liu W, Ardasheva A, Fu XY, Wang XM, Joshi P, Lee V, Dura B, Viero G, Iwasaki A, Fan R, Xiao A, Flavell RA.*, Li HB*, Tebaldi T*, Halene S*,m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development.,Immunity,2020,52, 1-15.[Link]

  • Yajuan Hao, Ph.D. Associate Professor Email: haoyajuan@sjtu.edu.cn
    Yongbo Liu, Ph.D. Associate Professor Email: Yongbo.Liu@shsmu.edu.cn
    Kaiqiong Mao, M.S. Administrative Assistant Email: kaiqiong.mao@sjtu.edu.cn
    Mei Yang, M.S. Lab Manager Email: yangmei@shsmu.edu.cn
    Yatao Zhou, M.S. Technician Email: zhouyatao@sjtu.edu.cn
    Sheng Hu, M.S. Technician Email: husheng946@163.com
    Ting Zhang, Ph.D. Postdoctoral Fellow(2017) Email: zhangting@shsmu.edu.cn
    Zhibin Yu, Ph.D. Postdoctoral Fellow(2018) Email: yuzhibin@sjtu.edu.cn
    Xingli Zhang, Ph.D. Postdoctoral Fellow(2019) Email: zhangxingli@shsmu.edu.cn
    Jing Zhou, Ph.D. Postdoctoral Fellow(2019) Email: jingzhou@shsmu.edu.cn
    Xuefei Wang, Ph.D. Postdoctoral Fellow (2019) Email: wangxf@shsmu.edu.cn
    Jingyu Li, Ph.D. Postdoctoral Fellow(2020) Email: lijy@shsmu.edu.cn
    Shan Miao Ph.D. student (2019) Email: shan.miao@sjtu.edu.cn
    Yinong Chao Ph.D. student (2017) Email: ValentChao@126.com
    Huifang Chen M.S. student (2018) Email: chenhuifang@sjtu.edu.cn