Quan Zheng

  Assistant Researcher  

  Ph.D. in Cell Biology, Shanghai Jiao Tong University School of Medicine

  B.S. in Biotechnology, Huazhong Agricultural University

  Email: tczq0236@163.com

  Office: Room 403, East 5 building

 Postdoctor:

01/2017 – 01/2020, Shanghai Jiao Tong University School of Medicine, preclinical medicine, postdoctor. 

Grants:

1) China Postdoctoral Science Foundation, 2017M611583, 07/2017-07/2019

2) National Natural Science Foundation of China, 81902673, 01/2020-12/2022

Publication：

1. Guo H, Xu J, Zheng Q, et al.. NRF2 SUMOylation promotes de novo serine synthesis and maintains HCC tumorigenesis. Cancer Lett. 2019 Dec 1;466:39-48. (IF=6.508)

2. Liang Q, Zheng Q, et al.. SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. Cell Rep. 2019 Aug 20;28(8):2004-2011. (IF=7.815)

3. Wang T, Cao Y, Zheng Q, et al.. SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism. Mol Cell. 2019 Aug 22;75(4):823-834. (IF=14.548)

4. Zheng Q, Cao Y, et al.. Senp2 regulates adipose lipid storage by de-SUMOylation of Setdb1.J Mol Cell Biol. 2018 Jun 1;10(3):258-266. (IF=5.595)

Patents:

1) Identification and application of compounds in regulating SENP1 phosphorylation and SIRT3 SUMOyaltion, 201711349811.2;

2) Biomarkers for diagnosis, treatment and prognosis of luminal or HER2-positive breast cancer, 201910420781.2;

3) Application of autocrine VEGFB in T cell metabolism, function and tumor immunotherapy, 201910613188.X;