Shanghai Institute of Immunology & Department of Immunology and Microbiology
Shanghai Institute of Immunology & Department of Immunology and Microbiology

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LU Liming

Immunoregulation Research Group

Tel: 63846590-776723

Email: lulunew2003@163.com

Laboratory of Immunoregulation

Research Field

  • Immune tolerance in allogenic organs;

  • Mechanism and clinical research of immunotherapy;;

  • Clinical applications and mechanism study of mesenchymal stem cells;

  • Investigation of Chinese Traditional Medicine drug Trichosanthin (Tk) and its derived peptides in immunomodulation.

Personal Introduction

  • Professor, PhD Supervisor

  • Principle Investigator of Immunomodulation Research Group

  • Executive-Editor-in-Chief of Journal of Current Immunology

  • Shanghai Oriental Talent

  • Shanghai Pujiang Talent

  • Shanghai Shuguang Scholar

  • Shanghai Science and Technology Enlightened Star Talent Program

  • Backbone Teacher of Shanghai Municipal Education Commission

  • Outstanding Youth in Shanghai Health System

  • Morning Star Scholar of Jiaotong University

  • New Hundred Talents of Medical College

Education

  • 1994-1998 Xiamen University, B.S.

  • 1998-2001 Shanghai Jiao Tong University School of Medicine, M.S.

  • 2003-2006 Shanghai Jiao Tong University School of Medicine, Ph.D.

Career

  • 2001-2003 Leader, Shanghai Tissue Engineering Research and Development Center

  • 2006-2008 Lecturer, Shanghai Jiao Tong University School of Medicine

  • 2009-2014 Shanghai Jiao Tong University School of Medicine, Associate Researcher, M.S. Supervisor, RBL Supervisor

  • 2014-Present PI, Professor, PhD Supervisor, Shanghai Jiao Tong University School of Medicine, Executive Editor-in-Chief of Journal of Current Immunology

  • 2012-2020 Director of experimental center of Shanghai Chest hospital

  • 2013-2014   Senior Visiting Scholar, Cambridge University

  • 2018.03-07  Project evaluation expert in National natural science foundation of China

Social Service

  • Deputy Secretary-General of Shanghai Society of Immunology

  • Vice Chairman, Pregnancy Immunology Branch, Shanghai Medical Association

  • Vice Chairman, Genetics Professional Committee, Shanghai Society for Immunology

  • Standing Council Member, Shanghai Society for Immunology

  • Standing Committee Member of Basic Immunology Branch, Asia-Pacific Medical and Biological Immunology Society

  • Standing Committee Member, Transplantation Immunology Professional Committee of Shanghai Society for Immunology

  • Standing Committee Member, Experimental Hematology Professional Committee, Chinese Society of Pathophysiology

  • Standing Committee Member, Cell Therapy Quality Control and Research Committee, China Association of Pharmaceutical Quality Management

  • Standing Committee Member, Oncology Branch, Chinese Medical and Biological Immunology Society

  • Council Member of Asia-Pacific Medical and Biological Immunology Society

  • Editorial Committee Member, Chinese Journal of Cancer Biotherapy

  • Member, Science Popularization and Teaching Committee, Chinese Society of Immunology

  • Member, Women Scientists Committee, Chinese Society of Immunology

  • Member, Infection Immunology Committee, Shanghai Society for Immunology

  • Member, Vaccination Committee, Pediatrics Branch, Chinese Medical Association

  • Member, Biotherapy Professional Committee, Chinese Research Hospital Association

  • Member, Tumor Immunology Committee, Shanghai Society for Immunology

  • Council Member, Shanghai Periodical Association

  • Standing Committee Member, Chinese Society of Immunotherapy

Scientific Research Grants

Host Projects:

  • Key project at central government level(2060302), The ability establishment of sustainable use for valuable Chinese medicine resources, 2024-2026

  • National Natural Science Foundation of China Grants (82071856), Application of Trichosanthin as an immunosynergist for group A meningitis vaccine,, Principal Investigator, 2021-2024

  • Basic clinical cross-project of Shanghai Institute of Immunology, Study on therapeutic resistance of head and neck hypopharyngeal tumors and mechanism of VEGFA+PD-L1+ neutrophils promoting tumor immune escape in microenvironment, 2024

  • Program for scientific and technological innovation from the Science and Technology Commission of Shanghai Municipality (22490760400)，Feasibility study of trichosanthin as a high-potency enhancer of novel coronavirus vaccine derived from stem cells, 2022-2025

  • National Major Basic Science R & D Program, Ministry of Science and Technology(2017YFA0104600). Reconstruction and regulation mechanism of the adaptive immune system post haploid genotype match transplantation, Principal Investigator, 2017-2021

  • National Natural Science Foundation of China Grants（81671579）, Suppression of lung allo-transplantation chronic rejection by Trichosanthin-derived Peptide induced Treg, , Principal Investigator,2017-2020

  • National Natural Science Foundation of China Grants（31370904）, The molecular immunology mechanism of CIITA regulating Th2 via NLR signal pathway,  Principal Investigator, 2014-2017

  • National Natural Science Foundation of China Grants（30972691）, Comparative Study on Immunobiological Properties of Th9 Subset and IL-9+IL-10+T Cells induced by Trichosanthin-derived Peptide tetramer, Principal Investigator, 2010-2012

  • National Natural Science Foundation of China Grants（30700766）, Functional Knockout of Mouse MHC by transgene a CIITA mutant and the analysis of the underlying mechanisms, Principal Investigator, 2008-2010

  • Shanghai Science and Technology Commission Experimental Animal Project（18140903800），Exploring the construction of a double humanized PDX model for lung cancer and the evaluation of drug treatment options for clinical patients, Principal Investigator, 2018-2021

  • Shanghai Municipal Bureau of Traditional Chinese Medicine Project（2020JP009）, The role of histone demethylase LSD1 on the maintenance of CD8+ Treg profile induced by Trichosanthin, Principal Investigator,2020-2022

  • Shanghai Science-Technology Foundation Key Program（15401900500）, Pharmacodynamics study of Trichosanthin active components in the regulation of Treg, Principal Investigator, 2015-2018

  • Shanghai Shuguang Scholar Program（16SG14）, Mechanism of treatment of OB using Trichosanthin-derived peptide, Principal Investigator, 2017-2019

  • Shanghai Pujiang Talent Program（15PJD021），Mechanism of using Trichosanthin-derived peptide in the treatment of Th1 dominant diseases, Principal Investigator, 2015-2017

  • Shanghai Science and Technology Council Program（14DZ1931003）, Translational research of lung cancer treatment using immune cells, Principal Investigator, 2014-2017

  • Shanghai youth science and technology star talent program（10QA1405900）, Application of trichosanthin derived peptide tetramer

  • Basic research key project of Shanghai Science and Technology Commission（11JC1410802），Application of regulatory T cells to inhibit chronic immune rejection in lung transplantation

  • Shanghai health system new excellent youth talent training program（2011XYQ015），Immunobiological characteristics and application of IFN-(R+IL-10R+Tr1) cells

  • Shanghai Municipal Education Commission（jdy06003），Study on the mechanism of co-stimulatory molecule B7-H1 inducing the production of regulatory T cells

  • Shanghai Municipal Education Commission（2685619），Immunobiological characterization of regulatory T cells induced by mCIITA molecule combined with B7-H1

Participating Projects:

  • National Major Basic Science R & D Program, Ministry of Science and Technology（2024YFA1107301）, Research and Development of Innovative Stem Cell and Derivative Drugs and Study of Regulatory Evaluation Technologies, 2024-2027

  • National Major Basic Science R & D Program, Ministry of Science and Technology, Clinical study of human umbilical cord mesenchymal stem cells in the treatment of optic neuromyelitis optica spectrum disease, 2020YFA010045, 2021-2025

  • 973 Grant from the Ministry of Science and Technology of China, Study on Tissue stem cell stemness maintenance, control of differentiation and immune regulation, 2010CB945600

  • National Natural Science Foundation of China Grants, The significance of epigenetic control in Th1/Th2 differentiation and MHC transcriptional activation, 30530690

Publications

1. Huizhuang Shan, Youping Zhang, Xinhua Xiao, Wenxuan Wu, Yingying Wang, Chujiao Zhu1, Wenhui Bai, Ziwei Zhang, Yuanhui Zhai, Li Yang, Yunzhao Wu, Hu Lei, Hanzhang Xu, Yanfei Luo, Liming Lu*, Yingli Wu*. USP7 sustains hematopoietic stem cell homeostasis partially via PU.1 stabilization. International Journal of Biological Sciences. 2026; 22(2): 1036-1052.
2. Feng Z, Li CS, Fu H, Jiang W, Zhang W, Huang Y, Huang Y, Tam TTKK, Li Y, Liu F, Liming Lu, Lee YL, Yeung WSB, Dougan G, Liu P. A Novel Human Cellular System for Studying Normal Aging and for Anti-Aging Discovery. Aging Cell. 2026 Feb;25(2):e70352.
3. Hu Y, Wu L, Qu S, Kong WT, Yu X, Xu J, Xu Z, He J, Wang C, Liu Z, Liming Lu, Ng LG, Blériot C, Su B, Ginhoux F, Li Z, Chakarov S. Temporal and spatial atlas of eosinophil specialization across tissues. Nat Immunol. 2026 Feb;27(2):364-375.
4. Anmin Ren, QianjunLiu, QianGan, Liming Lu, XinKaiQu. Associations of Inflammatory Markers and Coronary Heart Disease in Different Gender Groups in Cohort NHANES 2003-2018. Cardiol Res Pract. 2026 Feb 3;2026:5555602
5. Liu D, Wang X, Han Y, Wang J, Sun Y, Hou Y, Wu Q, Zeng C, Ding X, Chang Y, Hu J, Huang X, Liming Lu*. A donor PD-1+CD8+ TSCM-like regulatory subset mobilized by G-CSF alleviates recipient acute graft-versus-host-disease. Signal Transduct Target Ther. 2025 Apr 2;10(1):120.
6. Ng LG, Ballesteros I, Cassatella MA, Egeblad M, Fridlender ZG, Gabrilovich D, Gao Q, Granot Z, Grieshaber-Bouyer R, Grimes HL, Hedrick CC, Hidalgo A, Kaplan MJ, Kubes P, Ling GS, Liming Lu, Luo HR, Mayadas TN, Moutsopoulos NM, Ng M, Nigrovic PA, Ostuni R, Pittet MJ, Quail DF, Silvestre-Roig C, Soehnlein O, Udalova IA, Xue R, Zhang N, Kwok I. From complexity to consensus: A roadmap for neutrophil classification. Immunity. 2025 Aug 12;58(8):1890-1903.
7. Liu JG, Yu L, Guo XL, He XM, Li M, Gao RY, Zhao BH, Li QY, Zhu WJ, Xu P, Gu XH, Chen YA, Yin XL, Shang Y, Guo ZH, Mao JH, Hu YX, Liming Lu, Hua J, Zhang H, Li Y. Characterizing the immune landscape of tumor-infiltrating lymphocytes in non-small cell lung cancer. Genes Immun. 2025 May 5.
8. Zhang D, Heng Y, Jin QY, Tang D, Zhu XK, Liming Lu*, Wu CP, Tao L. Prognostic significance of cytotoxic-T-lymphocytes to immunosuppressive lymphocytes ratio (CIL) in laryngeal squamous cell carcinoma. Cancer Immunol Immunother. 2025 Mar 24;74(5):157.  
9. Zhang L, Lin L, Xiao B, Huang K, Liu J, Chen YL, Liming Lu, Zhang Z, Zhang L, Li J, Ho KT, Luo L, Huang SY, Li G. Eicosapentaenoic acid (EPA) reduced lipopolysaccharide-stimulated inflammatory response of RAW264.7 cells via the miR-125b-5p/CREB axis. Int J Biol Macromol. 2025 May;310(Pt 4):143511.  
10. Lin H, Ma J, Heng Y, Zhu X, Jin Q, Ding X, Tao L, Liming Lu*. CD8+ T cells in patients with hypopharyngeal squamous cell carcinoma are susceptible to radiation-induced damage. Int J Cancer. 2025 May 15;156(10):2010-2023.  
11. Zhu X, Heng Y, Ma J, Zhang D, Tang D, Ji Y, He C, Lin H, Ding X, Zhou J, Tao L, Liming Lu*. Prolonged Survival of Neutrophils Induced by Tumor-Derived G-CSF/GM-CSF Promotes Immunosuppression and Progression in Laryngeal Squamous Cell Carcinoma. Adv Sci (Weinh). 2024 Dec;11(46):e2400836.  
12. Zhang Y, Ding X, Zhang Q, Zeng C, Chen H, Liming Lu*. Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx. J Adv Res. 2024 Nov 4:S2090-1232(24)00493-4.  
13. Wang QL, Lu SY, Xu DD, Ma JX, Guo R, Zhang L, Tang LY, Shen Y, Shen CL, Wang JJ, Wu YL, Liming Lu, Wang ZG, Zhang HX. USP47 deficiency in mice modulates tumor infiltrating immune cells and enhances antitumor immune responses in prostate cancer. Cancer Immunol Immunother. 2024 Jun 4;73(8):143.
14. Qu X, Guan S, Cai J, Gan Q, Han W, Liming Lu, Fang W, Yin P, Shi H, Wang A, G Y, Zhou M, Huo Y. Reperfusion strategies on the clinical outcomes of ST-elevation myocardial infarction patients over 80 years old in China. Eur Heart J Qual Care Clin Outcomes. 2024 Feb 9:qcae013.
15. Ji Y, Heng Y, Zhu X, Zhang D, Tang D, Zhou J, Lin H, Ma J, Ding X, Tao L, Liming Lu*. Increased tumor-infiltrating plasmacytoid dendritic cells express high levels of PD-L2 and affect CD8+ T lymphocyte infiltration in human laryngeal squamous cell carcinoma. Transl Oncol. 2024 Jul;45:101936.  
16. Ma J, Zhu X, Heng Y, Ding X, Tao L, Liming Lu*. Establishment and characterization of a novel hypopharyngeal squamous cell carcinoma cell line CZH1 with genetic abnormalities. Hum Cell. 2024 Mar;37(2):546-559.    
17. Zhu X, Heng Y, Zhang D, Tang D, Zhou J, Lin H, Ma J, Ding X, Tao L, Liming Lu*. Prognostic significance and immune escape implication of tumor-infiltrating neutrophil plasticity in human head and neck squamous cell carcinoma. Hum Cell. 2024 May;37(3):714-728.  
18. Zhou D, Xu W, Ding X, Guo H, Wang J, Zhao G, Zhang C, Zhang Z, Wang Z, Wang P, Lu L, Yuan M. Transient inhibition of neutrophil functions enhances the antitumor effect of intravenously delivered oncolytic vaccinia virus. Cancer Sci. 2024 Apr;115(4):1129-1140.
19. Yuanyuan Mei, Xiaoting Sun, Shi-Ying Huang, Xiaowen Wu, Kuo-Ting Ho, Liming Lu, Chaoxiang Chen, Jian Li, Jingwen Liu, Guiling Li. Curcumin Prevents Free Fatty Acid-Induced Lipid Accumulation via Targeting the miR-22-3p/CRLS1 Pathway in HepG2 Cells. Polish Journal of Food and Nutrition Sciences. 2024; 74(1): 59–68
20. Jie Shu, Kefan Wang, Yuting Liu, Jie Zhang, Xuping Ding, Hanxiao Sun, Jiaoxiang Wu, Biao Huang, Ju Qiu, Huiming Sheng, Liming Lu*. Trichosanthin alleviates streptozotocin-induced type 1 diabetes mellitus in mice by regulating the balance between bone marrow-derived IL6+ and IL10+ MDSCs. Heliyon. 2023 Dec 12;10(1):e22907.  
21. Heng Y, Zhu X, Wu Q, Lin H, Ding X, Tao L, Liming Lu*. High Expression of Tumor HLA-DR Predicts Better Prognosis and Response to Anti-PD-1 Therapy in Laryngeal Squamous Cell Carcinoma. Transl Oncol. 2023 Jul;33:101678.  
22. Zhou L, Hou Y, Pan X, Wang X, Jin H, Yang X, Wang K, Ding X, Wang K, Zhu M, Pan Y, Wang W, Liming Lu*. Trichosanthin-derived peptide Tk-PQ attenuates immune rejection in mouse tracheal allotransplant model by suppressing PI3K-Akt and inducing type II immune polarization. Int Immunopharmacol. 2023 Oct 18;125(Pt A):111081.    
23. Zhang D, Tang D, Liu PT, Tao L, Liming Lu*. Isolation of tumor stem-like cells from primary laryngeal squamous cell carcinoma cells (FD-LS-6). Hum Cell. 2023 Sep 27.    
24. Lv QM, Lei HM, Wang SY, Zhang KR, Tang YB, Shen Y, Liming Lu*, Chen HZ, Zhu L. Cancer cell-autonomous cGAS-STING response confers drug resistance. Cell Chem Biol. 2023 Jun 15;30(6):591-605.e4.  
25. Heng Y, Zhu XK, Lin HQ, Ma JY, Ding XP, Zhang D, Tang D, Tao L, Liming Lu*. CD206+ tumor-associated macrophages interact with CD4+ tumor-infiltrating lymphocytes and predict adverse patient outcome in human laryngeal squamous cell carcinoma. Journal of Translational Medicine2023 Mar 3;21(1):167    
26. Yuting Liu, Kefan Wang,  Shuofei Yang, Guanhua Xue, Liming Lu*. Mulberry extract upregulates cholesterol efflux and inhibitsp38 MAPK-NLRP Mediated inflammation in foam cells. Food Sci Nutr. 2023 Mar 8;11(6):3141-3153.  
27. Ruan D, Ye ZW, Yuan S, Li Z, Zhang W, Ong CP, Tang K, Ka Ki Tam TT, Guo J, Xuan Y, Huang Y, Zhang Q, Lee CL, Liming Lu, Chiu PCN, Yeung WSB, Liu F, Jin DY, Liu P. Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection. Cell Rep Med. 2022 Dec 20;3(12):100849.
28. Lei HM, Zhang KR, Wang CH, Wang Y, Zhuang GL, Liming Lu, Zhang J, Shen Y, Chen HZ, Zhu L. Aldehyde dehydrogenase 1A1 confers erlotinib resistance via facilitating the reactive oxygen species-reactive carbonyl species metabolic pathway in lung adenocarcinomas. Theranostics. 2019 Sep 23;9(24):7122-7139.
29. Wang T, Zhang D, Tang D, Heng Y, Liming Lu*, Tao L. The role of systemic inflammatory response index (SIRI) and tumor-infiltrating lymphocytes (TILs) in the prognosis of patients with laryngeal squamous cell carcinoma. J Cancer Res Clin Oncol. 2022 Dec 15.    
30. Ma JX, Xu DD, Lu SY, Wang QL, Zhang L, Guo R, Tang LY, Shen Y, Shen CL, Wang JJ, Liming Lu, Wang ZG, Zhang HX. Stk10 Deficiency in Mice Promotes Tumor Growth by Dysregulating the Tumor Microenvironment. Biology (Basel). 2022 Nov 15;11(11):1668.  
31. Han Y, Ouyang X, Chen Y, Lai S, Sun H, Wu N, Ruan C, Liming Lu, Su B. scRNA-seq profiling of neonatal and adult thymus-derived CD4+ T cells by a T cell origin-time tracing model. J Mol Cell Biol. 2022 Dec 20:mjac072.
32. Rui Guo, Shun-Yuan Lu, Jin-Xia Ma, Qian-Lan Wang, Lu Zhang, Ling-Yun Tang, Yan Shen, Chun-Ling Shen, Jin-Jin Wang, Liming Lu, Zhu-GangWang, Hong-Xin Zhang, RIG-I acts as a tumor suppressor in melanoma via regulating the activation of the  MKK/p38MAPK signaling pathway. Hum Cell. 2022 Jul;35(4):1071-1083.
33. Di Tang, Duo Zhang, Yu Heng, Xiao-ke Zhu, Han-qing Lin, Jian Zhou, Lei Tao*, and Liming Lu*, Tumor-infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis. Journal of Inflammation Research. 2022 Feb. 16;15:1079-1097    4.2      
34. ZongAn Chen, Zhen Gao, LingLing Xia, XiaoQing Wang, Liming Lu*, XiaoLi Wu *. Dysregulation of DPP4-CXCL12 balance by TGF-β1/SMAD pathway promotes CXCR4+ inflammatory cell infiltration in keloid scars.Journal of Inflammation Research. 2021 Aug 26;14:4169-4180.  
35. Kai Wang, Man Zhang, Jiao Wang, Jizhuang Luo, Pan Sun, Haizhen Jing, Rong Li, Changqing Pan, Liming Lu*. A systematic analysis identifies key regulators involved in cell proliferation and potential drugs for the treatment of human lung adenocarcinoma.Frontiers in Oncology-Thoracic Oncology.2021 Sep28;11:4-15
36. Huidong Guo, Ruifeng Li, Ming Wang, Yingping Hou, Shuoshuo Liu, Ting Peng, Xiang-Yu Zhao, Liming Lu, Yali Han, Yiming Shao, Yingjun Chang, Cheng Li, and Xiaojun HuangMultiomics Analysis Identifies SOCS1 as Restraining T cell Activation and Preventing GVHD.J Exp Med . 2021Oct 09
37. Ke-Ren Zhang , Yu-Fei Zhang , Hui-Min Lei , Ya-Bin Tang , Chun-Shuang Ma , Qian-Ming Lv , Shi-Yi Wang , Liming Lu, Ying Shen , Hong-Zhuan Chen , Liang Zhu Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR- targeted therapy in lung cancer.Sci Transl Med2021 Oct 6;13(614):eabg6428.
38. Duo Zhang;Di Tang;Yu Heng; Xiao-Ke Zhu;Liang Zhou; Lei Tao; Liming Lu*. Prognostic Impact of Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma Patients. Laryngoscope. 2021 Apr;131(4):E1249-E1255    
39. Christopher D Nishimura, Marc C Pulanco, Wei Cui, Liming Lu, Xingxing Zang PD-L1 and B7-1 Cis-Interaction: New Mechanisms in Immune Checkpoints and Immunotherapies. Trends Mol Med.2020 Nov13;S1471-4914(20)30266-5.
40. ZhangYu; Zhou Lin; GuXiang; FengXuan; Ding Ping; Xia Qiang; Liming Lu*. CXCL8high inflammatory B cells in the peripheral blood of patients with biliary atresia are involved in disease progression. Immunology & Cell Biology.2020; 1–11  
41. Zhang, Na; Sun, Pan; Jin, Haizhen; Yang, Yuqin; Zhao, Qingya; Zhou, Lin; Guo, Lili; Yang, Xiaohua; Liming Lu*.Chidamide combined with paclitaxel effectively reverses the expression of histone deacetylase in lung cancer.Anti-Cancer Drugs. 2020 August; 31(7):702-708,  
42. Yi Xue , Di Tang , Sheng-Jie Li , Jian Zhou , Chi-Yao Hsueh , Dan-Dan Zhao , Yu Heng , Lei Tao, Liming Lu*. Link Between CIITA rs3087456 Polymorphism and the Risk of Laryngeal Squamous Cell Carcinoma in a Chinese Population.Pathol Res Pract. 2020 Jan;216(1):152793.  
43. Jian Zhou, Liang Zhou, Duo Zhang, Wei-Jing Tang, Di Tang, Xiao-Ling Shi, Yue Yang, Lin Zhou, Fei Liu, Yong Yu, Pentao Liu, Lei Tao, Liming Lu*. BCL11A promotes the progression of laryngeal squamous cell carcinoma.Frontiers in Oncology. 2020    
44. HeYu-Bin; GuoJiang-Hong; WangChong; ZhuDan; Liming Lu*. IL-33 promotes the progression of nonrheumatic aortic valve stenosis via inducing differential phenotypic transition in valvular interstitial cells. Journal of cardiology.2020 Feb;75(2):124-133.  
45. Gao, Xuefei; Nowak-Imialek, Monika; Chen, Xi; Chen, Dongsheng; Herrmann, Doris; Ruan, Degong; Chen, Andy Chun Hang; Eckersley-Maslin, Melanie A; Ahmad, Shakil; Lee, Yin Lau; Kobayashi, Toshihiro; Ryan, David; Zhong, Jixing; Zhu, Jiacheng; Wu, Jian; Lan, Guocheng; Petkov, Stoyan; Yang, Jian; Antunes, Liliana; Campos, Lia S; Fu, Beiyuan; Wang, Shengpeng; Yong, Yu; Wang, Xiaomin; Xue, Song-Guo; Ge, Liangpeng; Liu, Zuohua; Huang, Yong; Nie, Tao; Li, Peng; Wu, Donghai; Pei, Duanqing; Zhang, Yi; Liming Lu; Yang, Fengtang; Kimber, Susan J; Reik, Wolf; Zou, Xiangang; Shang, Zhouchun; Lai, Liangxue; Surani, Azim; Tam, Patrick P L; Ahmed, Asif; Yeung, William Shu Biu; Teichmann, Sarah A; Niemann, Heiner; Liu, Pentao. Establishment of porcine and human expanded potential stem cells. Nature cell biology, 2019, 21(6): 687. Establishment of porcine and human expanded potential stem cells. Nature cell biology, 2019, 21(6): 687.
46. Lin Ye, Yuqing Lou, Liming Lu and Xiaohong Fan. Mesothelin-targetedsecond generationCAR-T cellsinhibit growthof mesothelin-expressing tumorsin vivo. Exp Ther Med. 2019 Jan;17(1):739-747.
47. Yuanyuan Li, Mengyue Niu, Aonan Zhao, Wenyan Kang, Zhichun Chen, Ningdi Luo, Liche Zhou, Xiongwei Zhu, Liming Lu* and Jun Liu*. CXCL12 is involved in α-synuclein-triggered neuroinflammation of Parkinson’s disease. Journal of Neuroinflammation. 2019;16(1):263.  
48. Yi xue, Huai-Dong Du, Di Tang, Duo Zhang, Jian Zhou, Chang-Wen Zhai, Cun-Cun Yuan, Chi-Yao Hsueh, Sheng-Jie Li, Yu Heng, Lei Tao and Liming Lu*. Correlation Between the NLRP3 Inflammasome and the Prognosis of Patients With LSCC. FRONTIERS IN ONCOLOGY , 2019 , Jul 2;9:588  
49. Tu, G. W., Ju, M. J., Zheng, Y. J., Hao, G. W., Ma, G. G., Hou, J. Y., Zhang, X. P., Luo, Z.,  Liming Lu* CXCL16/CXCR6 is involved in LPS-induced acute lung injury via P38 signalling. Journal of cellular and molecular medicine, 2019 Aug;23(8):5380-5389.  
50. Jun Lu, Hua Zhong, Tianqing Chu, Xueyan Zhang, Rong Li, Jiayuan Sun, Runbo Zhong, Yuqin Yang, Mohammad Shah Alam, Yuqing Lou, Jianlin Xu, Yanwei Zhang, Jun Wu, Xiaowei Li, Xiaodong Zhao, Kai Li, Liming Lu*, Baohui Han. Role of anlotinib-induced CCL2 decrease in anti-angiogenesis and response prediction for non-small cell lung cancer therapy. European Respiratory Journal . 2019 Mar 1;53(3). pii: 1801562.  
51. Ma X, Li B, Li Y, Liming Lu, Chen H. A Pathologic Complete Response to Neoadjuvant Chemotherapy and Immunotherapy Followed by Surgery in a Patient With NSCLC. J Thorac Oncol. 2019 May;14(5):e104-e106.
52. Shen Y, Yan Y, Liming Lu, Qian Y, Guan X, Zhang L, Qi Y, Gu L, Ding F. Klotho ameliorates hydrogen peroxide-induced oxidative injury in TCMK-1 cells. Int Urol Nephrol. 2018 Apr;50(4):787-798.
53. Tang D, Zhao D, Wu Y, Yao R, Zhou L, Liming Lu*, Gao W, Sun Y. The miR-3127-5p/p-STAT3 axis up-regulates PD-L1 inducing chemoresistance in non-small-cell lung cancer. J Cell Mol Med. 2018 Aug;22(8):3847-3856.  
54. Tang D, Yao R, Zhao D, Zhou L, Wu Y, Yang Y, Sun Y, Liming Lu*, Gao W. Trichostatin A reverses the chemoresistance of lung cancer with high IGFBP2 expression through enhancing autophagy. Sci Rep. 2018 Mar 2;8(1):3917.  
55. Weimin Fan, Yali Xu, Yue Liu , Zhengqing Zhang , Liming Lu* and Zhide Ding，Obesity or Overweight, a Chronic Inflammatory Status in Male Reproductive System, Leads to Mice and Human Subfertility. Frontiers in Physiology, 2018,8:1117.  
56. Xiaoyan Yu, Yimin Lao, Xiao-Lu Teng, Song Li, Yan Zhou, Feixiang Wang, Xinwei Guo,  Siyu Deng,  Yuzhou Chang,  Xuefeng Wu,  Zhiduo Liu,  Lei Chen,  Liming Lu,  Jinke Cheng, Bin Li,  Bing Su,  Jin Jiang,  Hua-Bing Li,  Chuanxin Huang,  Jing Yi & Qiang Zou . SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation[J]. Nature communications, 2018, 9(1): 3157.
57. Xiaoyan Yu, XiaoLu Teng, Feixiang Wang, Yuhan Zheng, Guojun Qu, YanZhou, Zhilin Hu, Zhongqiu Wu, Yuzhou Chang, Lei Chen,HuaBing Li, Bing Su, Liming Lu*, Zhiduo Liu, ShaoCong Sun, and Qiang Zou. Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome. J Exp Med . 2018 Sep 3;215(9):2463-2476.  
58. Yue Wang, Qing Li, Lin Zhou, Xueping Ding, Liming Lu*. Peptede TK-PQ induces immunosuppression in skin allogeneic transplantation via increasing Foxp3+ Treg and impeding nuclear translocation of NF-κB. Molecular Immunology.2018 Sep;101:597-607.  
59. Xiao-yang Zhang, Lin Zhou, Zhen Guo, Ye Kong, Wei Zhang, Liming Lu*，Xin Li*, Regulatory T Cells may Play an Protection Role in Lung Injury after Operation in Rheumatic Heart Disease. Journal of Thoracic Disease, 2018 Jun;10(6):3196-3205.  
60. ZongAn Chen*, Lin Zhou*, TaeHao Won, Zhen Gao, XiaoLi Wuand Liming Lu*. .Characterization of Memory T Lymphocytes in Keloid Disease.Br J Dermatol. 2018 Apr;178(4):940-950.  
61. Yang Jian,Ryan David J,Wang Wei,Jason Cheuk-Ho Tsang, Guocheng Lan, Hideki Masaki, Xuefei Gao, Liliana Antunes, Yong Yu,  Zhexin Zhu, Juexuan Wang, Aleksandra A. Kolodziejczyk, Lia S. Campos, Cui Wang, Fengtang Yang, Zhen Zhong, Beiyuan Fu, Melanie A. Eckersley-Maslin, Michael Woods,  Yosuke Tanaka, Xi Chen, Adam C. Wilkinson, James Bussell,  Jacqui White, Ramiro Ramirez-Solis,  Wolf Reik, Berthold Göttgens, Sarah A. Teichmann, Patrick P. L. Tam, Hiromitsu Nakauchi,  Xiangang Zou, Liming Lu, Pentao Liu*. Establishment of mouse expanded potential stem cells.[J] .Nature, 2017, 550(7676): 393-397.
62. Zhang D, Zhou J, Tang D, Lei Tao, Liming Lu*. Neutrophil infiltration mediated by CXCL5 accumulation in the laryngeal squamous cell carcinoma microenvironment: A mechanism by which tumour cells escape immune surveillance. Clinical Immunology, 2017, 175: 34-40.
63. Tang Wei-Jing,Tao Lei, Liming Lu* et al. Role of T helper 17 cytokines in the tumour immune inflammation response of patients with laryngeal squamous cell carcinoma.[J] .Oncol Lett, 2017, 14(1): 561-568.
64. Zhou, J., Yang, Y., Zhang, D., Zhou, L., Tao, L., & Liming Lu*. Genetic polymorphisms and plasma levels of BCL11A contribute to the development of laryngeal squamous cell carcinoma. PloS one, 2017 Feb 22;12(2):e0171116.
65. Yu, Y, Tsang, C-H. J, Wang, C, Simon Clare, Juexuan Wang,Xi Chen, CordeliaBrandt, Leanne Kane, Lia S. Campos, Liming Lu, Gabrielle T. Belz, Andrew N. J. McKenzie,Sarah A.Teichmann, Gordon Dougan& Pentao Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its developmental pathway. Nature. 2016 Sep;539(7627)
66. Zhang, D, W. J. Tang, D. Tang, J. Zhou, L. Chou, L. Tao & Liming Lu*. The ratio of CD4/CD8 T-cells in human papillomavirus-positive laryngeal squamous cell carcinoma accounts for improved outcome. Acta Otolaryngol, 2016.136, 826-33.
67. Zhou, J, Y. Yang, D. Zhang, L. Zhou, F. Liu, L. Tao, Liming Lu*. Association of the recurrence of vocal leukoplakia with MDM2-309 variants over a 2-year period: a prospective study. Acta Otolaryngol, 2016.136, 95-9.
68. ZhouJ, D.Zhang, L. Zhou, Y. Yang, F. Liu, L. Tao, Liming Lu*. Association of the recurrence and canceration rate of vocal leukoplakia with interleukin-10 promoter variants over a 2-year period. Acta Otolaryngol, 2016. 136, 1147-1153.
69. Li Z, Yang N, Zhou L, Gu P, Wang H, Zhou Y, Zhou P, Liming Lu*, Chou KY. A peptide tetramer Tk-tPN induces tolerance of cardiac allografting by conversion of type 1 to type 2 immune responses via the Toll-like receptor 2 signal-promoted activation of the MCP1 gene. Immunology. 2016 Mar;147(3):355-66.
70. Tang D, Tang WJ, Shi XL, Li WP, Zhou H, Liming Lu*, Tao L. Association of the microsatellite (GT)n repeat polymorphisms of the HO-1 gene promoter and corresponding serum levels with the risk of laryngeal squamous cell carcinoma. Acta Otolaryngol. 2016 Aug;136(8):806-11.
71. Zhao AM, Xu HJ, Kang XM, Zhao AM, Liming Lu*.New insights into myeloid-derived suppressor cells and their roles in feto-maternal immune cross-talk. J Reprod Immunol. 2016 Nov 10;113:35-41.
72. Zhang D, Chen B, Zhou J, Zhou L, Li Q, Liu F, Chou KY, Tao L, Liming Lu*. Low concentration of Trichosanthin induces apoptosis and cell cycle arrest through JNK/MAPK activation. Molecular Medicine Report. 2015 Jan;11(1):349-56.
73. Zhou J, Yang Y, Zhang D, Zhou L, Liu F, Tao L, Liming Lu*. Association of the recurrence of vocal leukoplakia with MDM2-309 variants over a 2-year period: a prospective study. Acta oto-laryngologica 2015:1-5.
74. Yu Y, Wang C, Clare S, Wang J, Lee SC, Brandt C, Burke S1, Liming Lu , He D, Jenkins NA, Copeland NG, Dougan G, Liu P.. The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development. The Journal of experimental medicine 2015;212:865-74.
75. Tsang JC, Yu Y, Burke S, Buettner F, Wang C, Kolodziejczyk , Teichmann SA, Liming Lu*, Liu P, Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells. Genome Biol. 2015 Sep 21;16(1):178. doi:10.1186/s13059-015-0739-5.
76. Yang J, Wang W, Ooi J, Campos LS, Liming Lu*, Liu P Signalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem Cells. Stem Cells. 2015 May 33(5):1390-404.
77. Xuefei Gao, Jason C.H. Tsang, Fortis Gaba, Donghai Wu, Liming Lu*, Pentao Liu Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers. Nucleic Acids Research, 2014 2014 Nov 10;42(20):e155.
78. Tsang JC, Xuefei Gao, Liming Lu*, Pentao Liu Cellular reprogramming by transcription factor engineering. Current Opinion in Genetics & Development 2014, 28:1–9
79. Jian Zhou, Duo Zhang, Bin Chen, Qing Li, Lin Zhou, Fei Liu, Kuang-Yen Chou, Lei Tao, Liming Lu*. Association of interleukin 10 promoter polymorphisms and corresponding plasma levels with susceptibility to laryngeal squamous cell carcinoma ONCOLOGY LETTERS. 2014,7: 1721-1727.
80. F. Liu, X. Pan, L. Zhou, B. Chen, J. Shi, W. Gao and Liming Lu*. Genetic polymorphism and plasma levels of interleukin-22 contribute to the development of nonsmall lung cancer. DNA and CellBiology. 2014 Oct;33(10):705-14.
81. Zhou J, Liu F, Zhang D, Chen B, Li Q, Zhou L, Liming Lu*, Tao L. Significance of MDM2-309 polymorphisms and induced c orresponding plasma MDM2 levels in susceptibility to laryngeal squamous cell carcinoma DNA Cell Biol. 2014 Feb;33(2):88-94.
82. Neng Yang, Zuoqing Li, Zhijun Jiao, Peng Gu, Yun Zhou, Liming Lu*, Kuang-Yen Chou A Trichosanthin-derived peptide suppresses type 1 immune responses by TLR2-dependent activation of CD8+CD28−Tregs Clinic immunology (2013), 153, 277–287.
83. Bin Chen, Duo Zhang, Jian Zhou, Qing Li, Lin Zhou, Shi-Min Li, Li Zhu, Kuang-Yen Chou, Liang Zhou, Lei Tao, Liming Lu*. High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma. ONCOLOGY REPORTS 2013 30: 1380-1390.
84. Yang ZQ, Yang N, Zhou Y, Xin LJ, Liming Lu*, Chou KY. Mutated MHC class II transactivator upregulates IL-33-dependent differentiation of Th2 subset through Nod2 binding for NLR signaling initiation. Journal of Biological Chemistry, 2012 Mar 23;287(13) :9972-9981
85. Liu Y, Qu F, Cao X, Chen G, Guo Q, Ying X, Guo W, Liming Lu*, Ding Z. Con A-binding protein Zn-α2-glycoprotein on human sperm membrane is related to acrosome reaction and sperm fertility. International Journal of Andrology. 2012 Apr;35(2):145-157
86. Ding Q, Liming Lu*, Xiaorong Zhou, Zhou Y, Chou KY. Human PD-L1-overexpressing porcine vascular endothelial cells induce functionally suppressive human CD4+CD25hiFoxp3+ Treg cells. Journal of Leukocyte Biology, 2011 Jul, 90 (1):77-86.
87. Wang B, Jiao Z, Shao X, Liming Lu, Yang N, Zhou X, Xin L, Zhou Y, Chou KY. Phenotypic alterations of dendritic cells are involved in suppressive activity of trichosanthin-induced CD8+CD28- regulatory T cells. Journal of Immunology. 2010 Jul 1: 185(1):79-88
88. Zhou XR, Zhou Y, Ding Q, Liming Lu, Yang N, Chou KY. High level expression of B7H1 molecules by keratinocytes suppresses xeno- and allo- eactions by inducing type I regulatory T cells TransplantImmunology, 2009, 21: 192-197
89. Zhang J, Chen X, Zhang S, Zhou G, Xia X, Liming Lu*. Effects of transdermal estrogen therapy on expressions of estrogen receptors and T-lymphocyte apoptosis in surgically menopausal women. Cell Mol Immunol. 2009 Aug;6(4):277-83.  
90. Zhou XR, Yang N, Liming Lu, Ding Q, Jiao ZJ, Zhou Y, Chou KY. Up-regulation of IL-10 expression in dendritic cells is involved in Trichosanthin-induced immuno- suppression. Immunol Let 2007, 74-81.
91. Xiaorong Zhou,YangJiang, Liming Lu, Qing Ding,Kuang-Yen Chou. MHC class II transactivator represses human IL-4 gene transcription by interruption of promoter binding with CBP/p300, STAT6 and NFAT1 via histone hypoacetylation. Immunol, 2007,122,476-485.
92. Ding Q，Liming Lu, Wang BL, Zhou Y, Chou KY. B7H1-Ig fusion protein activates the CD4+IFNreceptor+ type 1 T regulatory subset through IFN--secreting Th1 cells. Journal of Immunology, 2006,177：3606-14.
93. Wang Kefan, Lu Liming*. Immune Cells: Key Regulators of Adipose Tissue Thermogenesis and Metabolic Disorders [J]. Modern Immunology, 2025, 45(05): 493-501.
94. Hu Yanan, Wang Kefan, Lu Liming*, Svetoslav Chakarov, et al. The Role of Eosinophils in Obesity and Related Diseases [J]. Modern Immunology, 2025, 45(02): 89-95.
95. Ding Xuping, Wang Kefan, Zeng Cong, Lu Liming*. Preparation and Immunomodulatory Function Exploration of Fluorescent Nanoparticles of Traditional Chinese Medicine Trichosanthin [J]. Chinese Journal of Medical Guide, 2025, 22(24): 28-33.
96. Zhang Duo, Lu Liming*. Heterogeneity of Tumor-Associated Neutrophils and Potential Clinical Significance. Chinese Journal of Cancer Biotherapy. 2024, 31(04)
97. Wang Xue, Pan Xufeng, Ding Xuping, Yang Jun, Hou Yafei, Jin Haizhen, Pan Yan, Zhu Minfang, Wang Weimin, Pan Changqing, Lu Liming*. Changes in Plasma IL-10 Levels After Allogeneic Lung Transplantation and Their Association with Death from Clinical Bacterial Infections in Recipients [J]. Modern Immunology, 2024, 44(01): 1-9+25.
98. Wang Xue, Lu Liming*. IRF4: A Key Molecule Regulating the Differentiation and Fate Determination of Multiple Immune Cell Lineages [J]. Modern Immunology, 2024, 44(02): 89-96.
99. Yang Ying, Li Zihan, Ding Xuping, Zhang Jiamin, Li Qin, Guo Zhonghui, Zhao Fengyong, Yang Qixiu, Wang Chen, Lu Liming, Zhu Ziyan. Confirmation of HLA Restriction of Tumor Antigen Peptides and Evaluation of the Tumor-Killing Ability of Induced Reactive T Cells [J]. Journal of Clinical Transfusion and Laboratory Medicine, 2024, 26(04): 433-439.
100. Shi Nianmin, Li Linkang, Shao Zhujun, Zhang Wenhong, Wu Jiang, Lv Min, Zheng Jiayin, Chen Zhiping, Liu Xiaoqiang, Zhang Hong, Tan Ying, Liu Xiaorong, Zhao Minghui, Luo Zhe, Lv Jicheng, Lu Liming*. Expert Consensus on the Combined Use of Meningococcal Vaccines and Complement Inhibitors in Populations with Complement-Related Kidney Diseases [J]. Chronic Pathematology Journal, 2023, 24(08): 1156-1159.
101. Jia Jingyi; Chen Qihan; Zhang Xinyu; Bai Tingyue; Lu Liming*. CD8~+ Treg: Subset Heterogeneity and Immunobiological Characteristics [J]. Modern Immunology, 2023, 43(06): 522-528.
102. Lin Hanqing, Tao Lei, Lu Liming*. CD4~+ Regulatory T Cells: Functional Heterogeneity, Subsets, and Diseases. Modern Immunology, 2022, 42(02): 89-96.
103. Yang Ying, Lu Liming, Li Qin, Guo Zhonghui, Yang Qixiu, Zhang Jiamin, Zhao Fengyong, Wang Chen, Zhu Ziyan. Induction of Specific Reactive T Cells from Donor PBMC by Tumor Neoantigen Peptides [J]. Journal of Clinical Transfusion and Laboratory Medicine, 2022, 24(05): 565-573.
104. Xuan Binbin, Ding Xuping, Hou Yafei, Wang Xue, Wu Jiaoxiang, Sun Hanxiao, Tan Meiyu, Sheng Huiming, Lu Liming*. Preliminary Study on Trichosanthin Enhancing the In Vitro Induction of CD4~+ Treg by Affecting the Ubiquitination Level of Foxp3 [J]. Modern Immunology, 2022, 42(03): 185-192.
105. Yang Ying, Lu Liming, Li Qin, et al. Induction of Specific Reactive T Cells from Donor PBMC by Tumor Neoantigen Peptides [J]. Journal of Clinical Transfusion and Laboratory Medicine, 2022, 24(05): 565-573.
106. Yang Xiaohua, Guo Lili, Lu Liming*. Establishment and Identification of a Taxol-Resistant In Situ Lung Transplanted Mouse Tumor Model. Chinese Journal of Experimental Animal Science, 2021(03): 275-283.
107. Ding Xuping; Wang Xue; Lu Liming*. Preliminary Study on Traditional Chinese Medicine Trichosanthin Enhancing the Induction of CD4~+CD25~+Foxp3~+ Regulatory T Cell Number and Function [J]. Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology, 2021, 23(11): 4097-4108.
108. Tang Chengjie, Shu Longqiang, Wu Yuankai, Zhao Liangjuan, Zhang Yifan, Hou Yafei, Lu Liming*. Research Progress on Immunosuppressive Subsets of Neutrophils and Their Functions and Mechanisms. Journal of Cellular and Molecular Immunology, 2020(09): 833-842
109. Fei Teng, Li Congzhen, Lu Liming*. TIM-3 Molecule and Tumor Immunosuppression. Chinese Journal of Cancer Biotherapy, 2020, 27(02), 199-203.
110. Xue Yi, Tang Di, Zhai Changwen, Yuan Cuncun, Heng Yu, Zhou Liang, Tao Lei, Lu Liming*. Relationship Between CⅡTA Expression and Prognosis in Patients with Laryngeal Squamous Cell Carcinoma (LSCC). Fudan University Journal of Medical Sciences, 2020(02): 192-196.
111. Shang Zhanxian, Lu Liming*. Research Progress on Neutrophils in Tumor Occurrence and Development. Modern Immunology, 2018(06): 488-492.
112. Heng Yu, Zha Yafang, Gu Yanni, Shen Chaobin, Lu Liming*. Interpretation of the 2018 U.S. Pediatric Immunization Guidelines and Comparison with the Current Situation in China. Modern Immunology, 2018, 38(04): 350-353.
113. Li Jian, Guo Zhen, Lu Liming*, Li Xin. Establishment of a Rat Cardiopulmonary Bypass Model Without Blood Priming [J]. Chinese Journal of Extracorporeal Circulation, 2018, 16(03): 184-188.
114. Chen Guangjie, Xie Changyi, Niu Xiaoyin, Jiang Lihua, Nie Hong, Lu Liming, Xi Yebin, Ge Hailiang. Practice and Research on the Integrated Course of Host Defense and Immunity [J]. Chinese Higher Medical Education, 2018 (4): 16-17.
115. Zhang Xiaoyang, Lu Liming*, Li Xin. Study on the Correlation Between Regulatory T Cells, Helper T Cells, and Lung Injury After Cardiopulmonary Bypass. Chinese Journal of Extracorporeal Circulation, 2017,15:81-85 Corresponding author.
116. Wan Jianwei, Zhou Lin, Zhao Dandan, Yang Yuqin, Lu Liming*. Effect of the Allene Compound PHPO on the Proliferation and Apoptosis of Lung Cancer Cell Line A549. Journal of Shanghai Jiaotong University (Medical Science), 2017,37:1433-1439.
117. Yu Haoran, Zhang Liuhui, Liu Wei, Zhou Lin, Ding Xuping, Jiang Lihua, Lu Liming*. The Role of RBL Teaching in Cultivating the Comprehensive Abilities of Clinical Medicine Undergraduates. Chinese Journal of Medical Education Research, 2016, 15(10): 1034-1038.
118. Zhou Lin, Gao Wen, Lu Liming*. Immunological Pathogenesis and New Treatment Strategies for Bronchiolitis Obliterans After Lung Transplantation. Modern Immunology, 2016, 36:67-71 Corresponding author.
119. Hu Minjuan, Na Jun, Hu Jingwen, Yang Xiaoqian, Heng Yu, Lu Liming*. Research Progress on Pathogen-Associated Proteins as Human Vaccine Adjuvants. Modern Immunology, 2016, 36:242-244 Corresponding author.
120. Yang Xiaoqian, Hu Jingwen, Na Jun, Hu Minjuan, Heng Yu, Lu Liming*. Research Progress on Non-Cytokine-Derived Natural Proteins as Human Vaccine Adjuvants. Modern Immunology, 2016, 36:245-249 Corresponding author.
121. Na Jun, Yang Xiaoqian, Hu Jingwen, Hu Minjuan, Heng Yu, Lu Liming*. Research Progress on Cytokine-Derived Natural Proteins as Human Vaccine Adjuvants. Modern Immunology, 2016, 36:337-340 Corresponding author.
122. Liu Fei, Xu Yi, Zhou Guangyan, Lu Liming.* Immunobiological Characteristics of CD8+ Treg and Their Relationship with Diseases. Modern Immunology, 2014, 34:61-66 Corresponding author.
123. Liu Fei, Pan Xufeng, Zhou Lin, Lu Liming.* Expression and Clinical Significance of Plasma microRNA-10b in Patients with Lung Adenocarcinoma. Chinese Journal of Practical Diagnosis and Therapy, 2014, 28(9): 846-848. Corresponding author.
124. Liu Fei, Zhou Guangyan, Lu Liming*. Biological Characteristics of Intracellular Pattern Recognition Receptor NLR and Its Role in Diseases [J]. Chinese Journal of Immunology, 2014, 12: 032.
125. Zhou Lin, Liu Fei, Zhou Guangyan, Lu Liming.* Effect of Trichosanthin on Apoptosis and Proliferation of Colon Cancer Cell Line CMT-93. Journal of Shanghai Jiaotong University (Medical Science), 2014,34(3):257-262. Corresponding author.
126. Shen Yue, Lu Liming*, Qian Yingying. Construction of a Eukaryotic Expression Vector for the Klotho Gene and Its Stable Expression in TCMK-1 Cells. Journal of Shanghai Jiaotong University (Medical Science), 2014,34(5):567-572.
127. Zhou Jian, Tao Lei, Zhang Duo, Chen Bin, Tang Weijing, Lu Liming.* Study on the Association Between Interleukin-10 Single Nucleotide Polymorphisms and Susceptibility to Vocal Cord Leukoplakia. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2013, 48: 1017-1021 Corresponding author.
128. Zhou Lin, Zhou Guangyan, Lu Liming*. Diversity and Plasticity of Helper T Cell Subset Differentiation [J]. Chinese Journal of Immunology, 2013, 29(06): 653-656.
129. Zhang Duo, Lu Liming, Chen Bin, Li Qing, Zhou Jian, Tao Lei. Trichosanthin Promotes Cisplatin-Induced Apoptosis in Laryngeal Cancer Cells by Inhibiting Nuclear Factor-κB. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2013, 48(4): 322-328.
130. Zhang Duo, Tao Lei, Lu Liming.* Mechanisms of Trichosanthin-Induced Tumor Cell Apoptosis and Other Anti-Tumor Effects: Research Progress. Fudan University Journal of Medical Sciences, 2012, 39(6): 663-667.
131. Zhou Lin, Zhou Guangyan, Lu Liming.* Bidirectional Immunomodulatory Effects of IL-10. Journal of Cellular and Molecular Immunology, 2012, 28(10): 1100-1102.
132. Chen Bin, Tao Lei, Zhou Liang, Zhou Guangyan, Lu Liming.* Correlation Between CD4+CD25+Foxp3+ Treg Cells and Laryngeal Cancer Pathogenesis. Modern Immunology, 2012, 32: 40-46 Corresponding author.
133. Li Qing, Zhou Guangyan, Lu Liming.* Preliminary Investigation into the Relationship Between Trichosanthin Inhibition of Allogeneic Mixed Lymphocyte Reaction and Induction of IL9+IL10+IL24+ Th9 Cells. Modern Immunology, 2012, 32(2): 94-98 Corresponding author.
134. Shao Xiaoyi, Ma Yanhui, Lu Liming*, et al. Study on B7H1-lg Inducing the Transformation of Tr1 Cells into CD4^+ CD25^+ Foxp3^+ Treg Cells. Modern Immunology, 2012, 6: 001.
135. Shao Xiaoyi, Zhou Yun, Lu Liming*. Role of the p38 MAPK Signaling Pathway in B7H1-Ig Fusion Protein-Induced Tr1 Cell Differentiation. Journal of Shanghai Jiaotong University (Medical Science), 2012, 32(11): 1448.
136. Shao Xiaoyi, Lu Liming*, Zhou Yun, et al. Mouse Membrane-Bound B7-H1 Molecule Activates Allogeneic Tr1 Cells to Mediate Immunosuppression. Journal of Nantong University: Medical Edition, 2012, 32(5): 333-337.
137. Li Qing, Zhou Guangyan, Lu Liming.* Th9: Subset Characteristics, Related Transcription Factors, and Differentiation Plasticity. Modern Immunology, 2011,31:340-343 Corresponding author.
138. Li Qing, Zhou Guangyan, Lu Liming.* Research Progress on IL-9. Chinese Journal of Immunology, 2011, 27:848-850 Corresponding author.
139. Chen Bin, Lu Liming, Tao Lei, Zhou Liang, Li Shimin, Zhu Li. Study on the Expression of Chemokine Receptors CCR6 and CCR7 in Laryngeal Squamous Cell Carcinoma [J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2010, 24(21): 975-979.
140. Chen Bin, Lu Liming, Tao Lei, Zhou Liang, Li Shimin, Zhu Li. Expression of Chemokine Receptors 6 and 7 and CD4+ CD25+ Foxp3+ Regulatory T Cells in Laryngeal Squamous Cell Carcinoma and Their Correlation with Lymphatic Metastasis. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2010, 45(9): 759-764.
141. Lu Liming, Ding Qing, Yang Neng, Zhou Yun, Zhou Guangyan. Study on Inhibition of MHC Class II Gene Expression and Function in Mouse L929 Cells Using RNA Interference, Modern Immunology, 2009, 28(6): 387-392.
142. Zhou Yun, Jiao Zhijun, Xin Lijun, Wang Siqi, Lu Liming, Ding Qing, Zhou Xiaorong, Yang Neng, Zhou Guangyan. Autologous Keratinocytes Inhibit Xenogeneic Mixed Lymphocyte Proliferation Through B7-H1 [J]. Modern Immunology, 2009, 29(06): 486-490.
143. Wang Hui, Yang Neng, Zhou Peijun, Shao Kun, Zhao Juping, Xu Da, Wang Xianghui, Shen Zhoujun, Lu Liming, Liu Shixiong. Adoptive Transfer of Mixed Cultured Donor and Recipient Bone Marrow Cells Prolongs Survival of Mouse Cardiac Allografts, Chinese Journal of Organ Transplantation, 2009, 30:604-607.
144. Zhou Yun, Jiao Zhijun, Lu Liming, Ding Qing, Yang Neng, Zhou Guangyan. Autologous Keratinocytes Inhibit Xenogeneic Mixed Lymphocyte Proliferation Reaction by Inducing IL-10-Secreting T Cell Subsets, Modern Immunology, 2009, 29:387-391.
145. Lu Liming, Ding Qing, Yang Neng, Zhou Yun, Zhou Guangyan. Preliminary Study on T Cells Induced by Membrane-Bound B7-H1 Molecule and Their Immunological Characteristics, Modern Immunology, 2008, 28(6):465-469.
146. Yang Neng, Lu Liming, Zhou Yun, Zhou Xiaorong, Jiao Zhijun, Ma Yanhui, Zhou Guangyan. Trichosanthin Synthetic Peptide Induces Immunosuppression by Activating Inhibitory CD8+ T Cells, Modern Immunology, 2008, 28(1): 16-20.
147. Yang Neng, Shi Guiying, Lu Liming, Zhou Yun, Ma Yanhui, Zhou Guangyan. Treatment of Experimental Autoimmune Encephalomyelitis by Trichosanthin Synthetic Peptide Through Induction of CD8 Inhibitory T Cells [J]. Modern Immunology, 2008(03): 199-202.
148. Xin Lijun, Jiao Zhijun, Ding Qing, Lu Liming, Zhou Yun, Zhou Guangyan. B7-H1 Co-stimulates Lymphocyte Proliferation and Induces Inhibitory T Cells [J]. Chinese Journal of Immunology, 2007(08): 680-683+687.
149. Lu Liming, Ding Qing, Jiang Yang, et al. Construction and Functional Study of a Novel CIITA Dominant Negative Mutant. Modern Immunology, 2006, 26:116-120.
150. Ding Qing, Lu Liming, Jiang Yang, et al. Mechanism Study on the Inhibitory Effect of B7H1-Ig Fusion Protein. Modern Immunology, 2006, 24(6): 460-463.
151. Jiao Zhijun, Wang Baolong, Lu Liming, Ding Qing, Zhou Xiaorong, Jiang Yang, Zhou Yun, Xin Lijun, Zhou Guangyan. Effect of Trichosanthin on T Cell Subset Differentiation in Different Mouse Strains. Modern Immunology, 2006, 24(1): 12-16.
152. Jiao Zhijun, Zhou Yun, Xin Lijun, Lu Liming, Ding Qing, Zhou Xiaorong, Yang Neng, Zhou Guangyan. Immunosuppression Induced by Trichosanthin and Its Peptides Depends on the Expression of Notch Ligands on APC Surface. Modern Immunology, 2006, 26(6): 448-453.
153. Jiao Zhijun, Zhou Yun, Lu Liming, Ding Qing, Zhou Xiaorong, Yang Neng, Xin Lijun, Zhou Guangyan. Screening of Functional Peptides of Trichosanthin for Immunosuppressive Activity and Their Mechanism of Action. Modern Immunology, 2006, 26(5): 362-366.
154. Cao Cong, Dong Yinghai, Dong Yuqi, Lu Liming, Cui Lei, Liu Wei, Cao Yilin. Culture of Human Blood-Derived Mesenchymal Stem Cells and Study on In Vitro Osteogenesis. Chinese Journal of Reparative and Reconstructive Surgery, 2005, 19(8): 642-647.
155. Zhou Hongyu, Lu Liming, Wang Yong, Jiang Jiyao, Luo Qizhong. Comparative Study on the Inhibition of Glioma Cell Proliferation by Elemene. Chinese Journal of Experimental Surgery, 2004, 21(10): 1241-1243.
156. Chen Wei, Liu Wei, Liu Deli, Wu Juanjuan, Lu Liming, Cao Yilin. The Role of FasL Gene-Transfected Hela Cells in Inducing Lymphocyte Apoptosis In Vitro. Journal of Shanghai Second Medical University, 2004, 24(4): 279-283.
157. Fan Huahua, Guo Rong, Cui Lei, Liu Wei, Lu Liming, Cao Yilin. Study on the Inhibitory Effect of CIITA Antisense Gene Transfection on HLA Class II Antigen Expression In Vitro. Chinese Journal of Clinical Medicine, 2004, 11(2): 174-176.
158. Jiang Yang, Lu Liming, Ding Qing, et al. Cloning, Identification, and Functional Assay of a Novel Variant of the Class II Transactivator (CIITA) Gene. Modern Immunology, 2004, 24(6): 460-463.
159. Li Ningli, Lu Liming, et al. Mechanism of Apoptosis Induced by Recombinant Human Soluble TRAIL Molecule. Journal of Shanghai Second Medical University, 2003, 23(1): 10-14.
160. Lu Liming, Li Ningli, Shen Baihua, et al. Preparation and Identification of Engineered Protein of the Extracellular Domain of TRAIL Molecule. Chinese Journal of Laboratory Diagnosis, 2003, 7: 477-479.
161. Zhou Hongyu, Lu Liming, Luo Qizhong. Primary Culture of Astrocytes from SD Rats. Chinese Journal of Neuromedicine, 2003, 2(5): 346-347.
162. Lu Liming, Li Ningli, et al. Cloning and Expression of Human Soluble TRAIL Gene. Shanghai Journal of Immunology, 2002, 22: 308-312.
163. Cheng Linling, Nie Hong, Wang Li, You Qiang, Lu Liming, Shen Baihua, Zhang Dongqing, Li Ningli. Cloning and Expression of Human sCD40L Gene. Journal of Cellular and Molecular Immunology, 2002(02): 125-127.

Textbook compilation

  • 《Compilation of Medical and Health Literature from the Republican Period》，Shanghai Scientific and Technological Literature Publishing House, Editor-in-Chief

  • 《Collected Publications on Modern Chinese Medicine》，Xueyuan Publishing House, Deputy Editor

  • 《Oral clinical immunology》，People's Medical Publishing House，Deputy Editor

  • 《Health and Immunology Popular Science Series: Infants and Toddlers Volume》，People's Medical Publishing House，Deputy Editor

  • 《JANEWAY’S IMMUNOBIOLOGY》, science press，editorial board member

  • 《Principles and Practice of Tissue Engineering》，Science Press, Editorial Committee Member

  • 《Immunological Techniques》, Science Press, Editorial Committee Member

  • 《Principles of Immunology》, Science Press, Editorial Committee Member

  • 《Textbook of Immunology》, Tsinghua University Press, Editorial Committee Member

  • 《Tumor Immunology》, Tsinghua University Press, Editorial Committee Member

  • 《Medical Immunology》, Tsinghua University Press, Editorial Committee Member

  • 《Medical Immunology and Laboratory Testing》, Science Press, Editorial Committee Member

  • 《Experimental Techniques in Oral Clinical Immunology》, People's Medical Publishing House, Editorial Committee Member

  • 《Ideological and Political Education Textbook in Immunology》, Science Press, Editorial Committee Member

  • 《Health and Immunology Popular Science Series: Disease Diagnosis and Prevention Volume》, People's Medical Publishing House, Editorial Committee Member

Patent

  • Application of trichosanthin activated TLR7 in enhancing the immunoprotective efficacy of novel coronavirus vaccine (Patent Number or Application Number: 202410938609. 7).

  • Application of trichosanthin in the preparation of drugs for the prevention or treatment of inflammatory bowel disease (Patent Number or Application Number: 202410862475.5).

  • Use of trichosanthin in the preparation of drugs to treat obesity caused by a high-fat diet (Patent Number or Application Number: 202410862474.0).

  • Human hypopharyngeal squamous cell carcinoma cell line and its application (Patent Number or Application Number: 202311408950.3).

  • Application of IRF4 in preparing kits for predicting prognosis of allogeneic hematopoietic stem cell transplantation recipients (Patent Number or Application Number: CN202210501546.X.).

  • Construction and application of a Chinese lung squamous carcinoma cell line (Patent Number or Application Number: 202010547005.1).

  • Application and induction of a new CD8+ regulatory T cell in immune regulation (Patent Number or Application Number: 202010965416.2).

  • Construction and application of a Chinese esophageal squamous carcinoma cell line (Patent Number or Application Number: 202010558292.6).

  • Construction and application of a Chinese lung adenocarcinoma cell line (Patent Number or Application Number: ZL 201710426801.8).

  • PHOP Application for treating lung cancer (Patent Number or Application Number: ZL 201710373254.1).

  • Application of Trichosanthin in enhancing vaccine specific antibodies (Patent Number or Application Number: ZL201610049358.2).

  • Screen of immunosuppressive effective epitope of Trichosanthin (Patent Number or Application Number: ZL201210390572.6).

  • Trichosanthin derived peptide and its application (Patent Number or Application Number: ZL200710173408.9).

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