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LV Jiangteng

E-mail: jiangtenglu@shsmu.edu.cn

Tel: 13262748253

Laboratory of Assembly and Operation of Prefrontal Cortical Circuits

Research Field: Assembly and operation    of prefrontal     cortical circuits

Personal Introduction

Jiangteng Lv, professor of Neurobiology in Shanghai Jiao Tong University College of Basic Medical Science. Research in Lu Lab aims to (1) analyze the structure and function of neural circuits in prefrontal cortex based on cell typing; (2) Dissect the Cytological and neural circuits mechanisms of synaptic inhibition at the  axon initial segment.

Education and Training

  • PEKING University, Bachelor, 1996-2000

  • Institute of Neuroscience, Chinese Academy of Science Center, Doctor, 2000-2007

  • Cold Spring Harbor Laboratory, Postdoctor, 2007-2018

  • Shanghai Jiao Tong University College of Basic Medical Science, professor, 2018-now.

Scientific Research Projects

  • 2018.12.01-2021.11.30, Grant from Shanghai Science and Technology Committee. (18JC1420302).

  • 2020.01.01-2023.12.31, Dissect the contribution of synaptic inhibition at axon initial segment to the operation of cortical neuronal circuits, National Natural Science Foundation of China.

  • 2022.05.01-2025.04.30, Dissect the role and mechanism of chandelier cells in cognitive impairment, the Program of Shanghai Academic/Technology Innovation Action Plan.

  • 2021.12.01-2026.11, Grant from the Ministry of Science and Technology of the People's Republic of China (2021ZD0202800).

Publications

  1. Lu J#, Tucciarone J#, et al. Selective inhibitory control of pyramidal neuron ensembles and cortical subnetworks by chandelier cells. Nat Neurosci, 2017, 20(10): 1377~1383

  2. Lu J, et al. Input-specific maturation of synaptic dynamics of parvalbumin interneurons in primary visual cortex. Proc Natl Acad Sci USA, 2014, 114(47): 16895~900

  3. Lu J, et al. Spike-timing-dependent plasticity of neocortical excitatory synapses on inhibitory interneurons depends on target cell type. J Neurosci, 2007, 27(36): 9711~972

  4. Li C#, Lu J# et al. Bidirectional modification of presynaptic neuronal excitability accompanying spike timing-dependent synaptic plasticity. Neuron, 2004, 41(2): 257~268