Lab Leader: Qian Zhao

Lab Name: Laboratory of RNA and Tumor Cell Fate Determination

Lab Info：Our lab mainly focuses on the important scientific issue of "RNA and tumor cell fate determination". Combining multiple approaches including molecular and cellular biology, biochemistry, mouse reverse genetics and state-of-art omics techniques, our research focuses on the following areas: (1) Abnormal expression of long non-coding RNA (lncRNA) in tumor metastasis as well as its function and molecular mechanism; (2) Abnormal expressive regulation of lncRNA in tumor microenvironments such as hypoxia; (3) The function and molecular mechanism of m1A RNA epigenetic modification in the evolution of liver cancer. The members of the lab have published more than 50 SCI papers in international academic journals such as Blood, Cell Death Differ, Cell Discovery and other journals. The achievements won the second prize of the National Natural Science Award; the first prize of the Chinese Medical Science and Technology Award; the first prize of the Shanghai Natural Science Award and other awards.

Lab Members: