Lab Leader: Xu Yue

Lab Name: Laboratory of Bacterial Infections and Host Innate Immunity

Lab Info：Our lab was established in early 2021 and mainly focuses on the mechanisms of pathogenic bacterial infection and host innate immune recognition. Mining from the pathogen side, our lab is devoted to identifying and analyzing the biochemical activities of bacterial effectors secreted into host cells during the infection process. This helps to elucidate the pathogenic mechanism of bacteria and provides an excellent entry point and novel tool for studying eukaryotic cell signaling pathways. From the side of eukaryotic cells, our lab combines biochemistry, genetic screening, and cell biology to identify and study host signaling pathways defending bacterial infection. And continue to explore the biological function of the novel non-canonical autophagy pathway (VAIL) based on our previous research. Relevant works have been published in international academic journals such as Cell, Nature Structural & Molecular Biology, Autophagy, mBio, etc.

Lab Members: