Lab Leader:Chen Fan

Lab Name:Laboratory of Smart Drug Delivery

Lab Info：

Mental disorders are diseases caused by dysfunctions of the brain's neural circuitry, leading to varying degrees of impairment in cognition, emotion, behavior, and volition. These include conditions such as schizophrenia, depression, and autism spectrum disorder. It is estimated that approximately one billion people worldwide are affected by mental disorders, with a trend of increasing prevalence year by year. The causes of mental disorders are highly complex and are generally believed to be associated with disruptions in the neurotransmitter systems of the brain. As a result, neurotransmitter-related proteins have become major drug targets for the treatment of mental disorders. Ion channels play a critical role in neurotransmitter-mediated neuronal signaling. Research into their regulatory mechanisms and pharmacology helps elucidate the underlying pathology of these diseases and guides drug development. Our research group focuses on drug targets related to neuropsychiatric disorders. By integrating interdisciplinary approaches such as structural biology, pharmacology, and computational biology, we investigate the mechanisms of novel targets and conduct research on the design and discovery of innovative drugs. The main research directions include:

1）Regulatory mechanisms of ion channel proteins associated with neuropsychiatric disorders

2）Pharmacological mechanisms of drugs used to treat neuropsychiatric disorders

3）Discovery of novel targets and design of innovative drugs for neuropsychiatric disorders

Lab Members: