仪器介绍:
Thermo Scientific™ LTQ Orbitrap XL™应用LTQ Orbitrap技术,为各种实验室提供突破性技术服务。通过强大的功能,稳定性以及低运行成本成为蛋白质组学和代谢组学应用的最佳选择,完全超过并替代Q-TOF系统。通过高分辨以及精确的质量分析能力,使组合式质谱系统实现差异表达的高通量无标记鉴定。LTQ Orbitrap XL其无与伦比的MS和MSn灵敏度、快速扫描速率、高质量精确度,高分辨能力,无疑是蛋白质鉴定和生物标记领域的理想选择。
应用领域及仪器特性:
Protein Identification
• High mass accuracy lowers false positive rates
• Parallel acquisition mode optimizes productivity
• High MS and MS/MS sensitivity, wide dynamic range and fast cycle times increase protein identifications

Biomarker Discovery
• HCD collision cell provides high fragmentation efficiency combined with high sensitivity for the reporter and fragment ions of the peptide sequence
• Reliable identification and quantification in one experiment
De novo Sequencing
• High mass accuracy and high resolution leads to high confidence de novo sequencing results
• Multiple collision modes (CID and HCD) provide comprehensive structural information
Metabolite Profiling and Identification
• High mass accuracy, sensitivity, and dynamic range enable reliable profiling of low-abundance metabolites in complex mixtures
• MSn spectral tree fingerprints distinguish between isobaric compounds
Thermo Scientific™ SIEVE™ and Mass Frontier™ software facilitate determination of differentially expressed metabolites
• Thermo Scientific™ MetWorks™ and Mass Frontier software automates structural elucidation