Biography

Dr. Gao obtained a Bachelor's degree of Maternity and child care from Peking University Health Science Center and Doctorate in Pediatrics from Shanghai Jiao Tong University School of Medicine. Dr. Gao focuses on how exposures that occur during critical and vulnerable periods of development may influence offspring’ health outcomes based on birth cohort studies. Her research work involves applying epidemiology, risk analysis, and toxicology to provide a comprehensive understanding of the risk and mechanism of environmental endocrine disruptors, not only traditional contaminants such as organophosphate or pyrethroid pesticides, and brominated flame retardants, but also emerging environmental contaminants such as perfluoroalkyl substances, personal care products, bisphenol A and organophosphorus flame retardants. She is responsible for building and maintaining Laizhou Wai Birth Cohort. She is also interested in epidemiologic methodology research and statistical models that could help us better address biases in observational studies, and explore the mixed effects of traditional and emerging environmental contaminants. Dr. Gao is leading several studies with funding from the National Natural Science Foundation of China and The Science and Technology Commission of Shanghai Municipality to evaluate whether fetal exposures to endocrine disrupting compounds could harm fetal growth and development leading to adverse health effects such as impaired neuropsychological function, obesity and disrupted reproductive function in childhood. She has published more than 50 papers in the field of influential magazines such as Environ Health Perspect, Environ Int, Environ Sci Technol, and Environ Res.

Publications

(Only list published as the first author or the corresponding author during the last 5 years)

1. Gao Y, Luo J, Zhang Y, Pan C, Ren Y, Zhang J, Tian Y; Shanghai Birth Cohort. Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Child Growth Trajectories in the First Two Years. Environ Health Perspect 2022,130(3):37006.

2. Pan C, Yu J, Yao Q, Lin N, Lu Z, Zhang Y, Zhao S, Wang Z, Lei X, Tian Y, Gao Y. Prenatal neonicotinoid insecticides Exposure, oxidative Stress, and birth outcomes. Environ Int 2022,163:107180.

3. Yao Q, Vinturache A, Lei X, Wang Z, Pan C, Shi R, Yuan T, Gao Y, Tian Y. Prenatal exposure to per- and polyfluoroalkyl substances, fetal thyroid hormones, and infant neurodevelopment. Environ Res 2022,206:112561.

4. Wang Z, Shi R, Ding G, Yao Q, Pan C, Gao Y, Tian Y. Association between maternal serum concentration of perfluoroalkyl substances (PFASs) at delivery and acute infectious diseases in infancy. Chemosphere 2022,289:133235.

5. Yao Q, Gao Y, Zhang Y, Qin K, Liew Z, Tian Y. Associations of paternal and maternal per- and polyfluoroalkyl substances exposure with cord serum reproductive hormones, placental steroidogenic enzyme and birth weight. Chemosphere 2021, 285:131521.

6. Zhang, Y.; Chen, D.; Shi, R.; Kamijima, M.; Sakai, K.; Tian, Y.; Gao, Y.; Indoor volatile organic compounds exposures and risk of childhood acute leukemia: a case-control study in Shanghai. Journal of Environmental Science and Health, Part A 2021,56(2):190-198

7. Hu, P.; Vinturache, A.; Li, H.; Tian, Y.; Yuan, Y.; Cai, C.; Lu, M.; Zhao, J.; Zhang, Q.; Gao, Y.; Liu, Z.; Ding, G.; Urinary Organophosphate Metabolite Concentrations and Pregnancy Outcomes among Women Conceiving through in Vitro Fertilization in Shanghai, China. Environmental Health Perspectives 2020, 128(9):97007.

8. Gao, Y.; Yu, Y.; Xiao, J.; Luo, J.; Zhang, Y.; Tian, Y.; Zhang, J.; Olsen, J.; Li, J.; Liew, Z., Association of Grandparental and Parental Age at Childbirth With Autism Spectrum Disorder in Children. JAMA Netw Open 2020, 3, (4), e202868.

9. Zhang, Y.; Ji, L.; Hu, Y.; Tse, L. A.; Wang, Y.; Qin, K.; Ding, G.; Zhou, Y.; Yu, X.; Ouyang, F.; Zhang, J.; Gao, Y.; Tian, Y.; Shanghai Birth Cohort, S., Exposure to Organophosphate Pesticides and Menstrual Cycle Characteristics in Chinese Preconceptional Women. Am J Epidemiol 2020, 189, (5), 375-383.

10. Yuan, L.; Zhang, Y.; Wang, W.; Chen, R.; Liu, Y.; Liu, C.; Kan, H.; Gao, Y.; Tian, Y.; Shanghai Birth Cohort, S., Critical windows for maternal fine particulate matter exposure and adverse birth outcomes: The Shanghai birth cohort study. Chemosphere 2020, 240, 124904.

11. Wang, Y.; Zhang, Y.; Ji, L.; Zhou, Y.; Shi, R.; Kamijima, M.; Ueyama, J.; Gao, Y.; Tian, Y., Prenatal exposure to organophosphate pesticides, maternal paraoxonase 1 genotype, and childhood neurodevelopment at 24 months of age in Shandong, China. Environ Sci Pollut Res Int 2020, 27, (2), 1969-1977.

12. Qin, K.; Zhang, Y.; Wang, Y.; Shi, R.; Pan, R.; Yao, Q.; Tian, Y.; Gao, Y., Prenatal organophosphate pesticide exposure and reproductive hormones in cord blood in Shandong, China. Int J Hyg Environ Health 2020, 225, 113479.

13. Hu, Y.; Zhang, Y.; Vinturache, A.; Wang, Y.; Shi, R.; Chen, L.; Qin, K.; Tian, Y.; Gao, Y., Effects of environmental pyrethroids exposure on semen quality in reproductive-age men in Shanghai, China. Chemosphere 2020, 245, 125580.

14. Ding, G.; Niu, L.; Vinturache, A.; Zhang, J.; Lu, M.; Gao, Y.; Pan, S.; Tian, Y.; Shanghai Birth Cohort, S., "Doing the month" and postpartum depression among Chinese women: A Shanghai prospective cohort study. Women Birth 2020, 33, (2), e151-e158.

15. Pan, R.; Wang, C.; Shi, R.; Zhang, Y.; Wang, Y.; Cai, C.; Ding, G.; Yuan, T.; Tian, Y.; Gao, Y., Prenatal Bisphenol A exposure and early childhood neurodevelopment in Shandong, China. Int J Hyg Environ Health 2019, 222, (5), 896-902.

16. Hu, Y.; Zhang, Z.; Qin, K.; Zhang, Y.; Pan, R.; Wang, Y.; Shi, R.; Gao, Y.; Tian, Y., Environmental pyrethroid exposure and thyroid hormones of pregnant women in Shandong, China. Chemosphere 2019, 234, 815-821.

17. Cai, C.; Chen, W.; Vinturache, A.; Hu, P.; Lu, M.; Gu, H.; Qiao, J.; Liu, F.; Tian, Y.; Gao, Y.; Ding, G., Thyroid hormone concentrations in second trimester of gestation and birth outcomes in Shanghai, China. J Matern Fetal Neonatal Med 2019, 1-9.

18. Hu, Y.; Ji, L.; Zhang, Y.; Shi, R.; Han, W.; Tse, L. A.; Pan, R.; Wang, Y.; Ding, G.; Xu, J.; Zhang, Q.; Gao, Y.; Tian, Y., Organophosphate and Pyrethroid Pesticide Exposures Measured before Conception and Associations with Time to Pregnancy in Chinese Couples Enrolled in the Shanghai Birth Cohort. Environ Health Perspect 2018, 126, (7), 077001.

19. Zhang, J.; Hu, Y.; Guo, J.; Pan, R.; Shi, R.; Tian, Y.; Zhou, Y.; Gao, Y., Fenvalerate decreases semen quality in puberty rat through germ cell apoptosis. Andrologia 2018, 50, (9), e13079.

20. Guo, J.; Shi, R.; Luan, Y.; Zhou, Y.; Gao, Y.; Tian, Y., Genotoxic effects of imidacloprid in human lymphoblastoid TK6 cells. Drug Chem Toxicol 2018, 1-5.

21. Chen, L.; Wang, C.; Zhang, Y., Zhou, Y.; Shi, R.; Cui, C.;Gao, Y.; Tian, Y., Polybrominated diphenyl ethers in cord blood and perinatal outcomes from Laizhou Wan Birth Cohort, China. Environ Sci Pollut Res Int 2018, 25(21):20802-20808.

22. Wang, Y.; Zhang, Y.; Ji, L.;Hu, Y.; Zhang, J.; Wang, C.; Ding, G.; Chen, L.; Kamijima, M.; Ueyama, J.; Gao, Y.; Tian, Y., Prenatal and postnatal exposure to organophosphate pesticides andchildhood neurodevelopment in Shandong, China. Environ Int 2017, 108, 119-126.

23. Ding, G.; Wang, C.; Vinturache, A.; Zhao, S.; Pan, R.; Han, W.; Chen, L.; Wang, Y.; Yuan, T.; Gao, Y.; Tian, Y., Prenatal low-level phenol exposures and birth outcomes in China. Sci Total Environ 2017, 607-608, 1400-1407.