YAN Chonghuai


Email:yanchk@qq.com, yanchk@gmail.com


Research Areas: pollutants AND children’s health, Heavy metals neurotoxicity


Prof. Yan is work in Department of Women and Children’s Health of School of Public Health, and he is also a Pediatrician in Xinhua Hospital of Shanghai Jiao Tong University School of Medicine.

Prof. Yan is a vice director of MOE-Shanghai Key Laboratory of Children’s Environmental Health since 2004. He is the director of Research Center of Childhood Lead Poisoning Prevention.

Prof. Yan has finished a national epidemiological investigation of heavy metal exposure levels of children in China. Dr. Yan wrote and drafted the Chinese version of the guidelines for the prevention of Childhood lead poisoning twice in 2005 and 2022. Dr. Yan has been invited in multiple national environmental advisory committees, and Expert Panels for children’s environmental health research to the Chinese government. He is serving as a standing member for both Public Health Branch of Chinese Medical Association, and Environmental Health Branch & Child Health Branch of Chinese Preventive Medicine Association.



  1. Richard Fuller, Philip J Landrigan, Kalpana Balakrishnan, Glynda Bathan, Stephan Bose-O’Reilly, Michael Brauer, Jack Caravanos, Tom Chiles, Aaron Cohen, Lilian Corra, Maureen Cropper, Greg Ferraro, Jill Hanna, David Hanrahan, Howard Hu, David Hunter, Gloria Janata, Rachael Kupka, Bruce Lanphear, Maureen Lichtveld, Keith Martin, Adetoun Mustapha, Ernesto Sanchez-Triana, Karti Sandilya, Laura Schaefli, Joseph Shaw, Jessica Seddon, William Suk, Martha María Téllez-Rojo, Chonghuai Yan. Pollution and health: a progress update - The Lancet Planetary Health. https://doi.org/10.1016/S2542-5196(22)00090-0

  2. Wang Y, Wang Y, Yan C. Gender differences in trace element exposures with cognitive abilities of school-aged children: a cohort study in Wujiang city, China. Environ Sci Pollut Res Int. 2022 Apr 27. doi: 10.1007/s11356-022-20353-4. Online ahead of print. PMID: 35474433

  3. Wang Y, Wang S, Wang Y, Lu A, Cao L, Wang J, Gao Z, Yan C. Effects of prenatal exposure to arsenic on neonatal birth size in Wujiang, China. Chemosphere. 2022 Mar 28;299:134441. doi: 10.1016/j.chemosphere.2022.134441. Online ahead of print.PMID: 35358562

  4. Dong C, Liu J, Harvey P, Yan C. Characteristics and sources of Pb exposure via household dust from the urban area of Shanghai, China. Sci Total Environ. 2022 Mar 10;811:151984. doi: 10.1016/j.scitotenv.2021.151984. Epub 2021 Dec 4.PMID: 34871683

  5. Wang J, Cao LL, Gao ZY, Zhang H, Liu JX, Wang SS, Pan H, Yan CH. Relationship between thyroid hormone parameters and exposure to a mixture of organochlorine pesticides, mercury and nutrients in the cord blood of newborns. Environ Pollut. 2022 Jan 1;292(Pt A):118362. doi: 10.1016/j.envpol.2021.118362. Epub 2021 Oct 12.

  6. Wang SS, Lu AX, Cao LL, Ran XF, Wang YQ, Liu C, Yan CH. Effects of prenatal exposure to persistent organic pollutants on neonatal Outcomes:A mother-child cohort (Shanghai, China). Environ Res. 2022 Jan;203:111767. doi: 10.1016/j.envres.2021.111767. Epub 2021 Aug 12.

  7. Zhang H, Wang S, Wang Y, Lu A, Hu C, Yan C. DHA ameliorates MeHg‑induced PC12 cell apoptosis by inhibiting the ROS/JNK signaling pathway. Mol Med Rep. 2021 Aug;24(2):558. doi: 10.3892/mmr.2021.12197. Epub 2021 Jun 10. PMID: 34109428 Free PMC article.

  8. Wang S, Hu C, Lu A, Wang Y, Cao L, Wu W, Li H, Wu M, Yan C. Association between prenatal exposure to persistent organic pollutants and neurodevelopment in early life: A mother-child cohort (Shanghai, China). Ecotoxicol Environ Saf. 2021 Jan 15;208:111479. doi: 10.1016/j.ecoenv.2020.111479. Epub 2020 Oct 21.

  9. Zhou CC, He YQ, Gao ZY, Wu MQ, Yan CH. Sex differences in the effects of lead exposure on growth and development in young children. Chemosphere. 2020 Jul;250:126294. doi: 10.1016/j.chemosphere.2020.126294. Epub 2020 Feb 21.

  10. Li MM, Gao ZY, Dong CY, Wu MQ, Yan J, Cao J, Ma WJ, Wang J, Gong YL, Xu J, Cai SZ, Chen JY, Xu SQ, Tong S, Tang D, Zhang J, Yan CH. Contemporary blood lead levels of children aged 0-84 months in China: A national cross-sectional study. Environ Int. 2020 Jan;134:105288. doi: 10.1016/j.envint.2019.105288. Epub 2019 Nov 22.

  11. Wang J, Wu W, Li H, Cao L, Wu M, Liu J, Gao Z, Zhou C, Liu J, Yan C. Relation of prenatal low-level mercury exposure with early child neurobehavioral development and exploration of the effects of sex and DHA on it. Environ Int. 2019 May;126:14-23. doi: 10.1016/j.envint.2019.02.012. Epub 2019 Feb 15.

  12. Wu MQ, Wu DQ, Yang Y, Zhou CC, Yan CH. Impact of delivery mode on the levels of essential trace elements in breast milk. J Matern Fetal Neonatal Med. 2020 Oct;33(19):3293-3299. doi: 10.1080/14767058.2019.1571035. Epub 2019 Jan 31.

  13. Zhou CC, Gao ZY, He YQ, Wu MQ, Chen F, Wang J, Liu JX, Yan CH.Effects of lead, mercury, aluminium and manganese co-exposure on the serum BDNF concentration of pre-school children in Taizhou, China. Chemosphere. 2019 Feb;217:158-165. doi: 10.1016/j.chemosphere.2018.11.028. Epub 2018 Nov 3.

  14. Chen F, Zhou CC, Yang Y, Liu JW, Yan CH. GM1 Ameliorates Lead-Induced Cognitive Deficits and Brain Damage Through Activating the SIRT1/CREB/BDNF Pathway in the Developing Male Rat Hippocampus. Biol Trace Elem Res. 2019 Aug;190(2):425-436. doi: 10.1007/s12011-018-1569-6. Epub 2018 Nov 9.

  15. Zhou CC, Gao ZY, Wang J, Wu MQ, Hu S, Chen F, Liu JX, Pan H, Yan CH. Lead exposure induces Alzheimers's disease (AD)-like pathology and disturbes cholesterol metabolism in the young rat brain. Toxicol Lett. 2018 Oct 15;296:173-183. doi: 10.1016/j.toxlet.2018.06.1065. Epub 2018 Jun 15.

  16. Gao ZY, Li MM, Wang J, Yan J, Zhou CC, Yan CH. Blood mercury concentration, fish consumption and anthropometry in Chinese children: A national study. Environ Int. 2018 Jan;110:14-21. doi: 10.1016/j.envint.2017.08.016. Epub 2017 Nov 4.

  17. Ying XL, Gao ZY, Yan J, Zhang M, Wang J, Xu J, Markowitz M, Yan CH. Sources, symptoms and characteristics of childhood lead poisoning: experience from a lead specialty clinic in China. Clin Toxicol (Phila). 2018 Jun;56(6):397-403. doi: 10.1080/15563650.2017.1391392. Epub 2017 Oct 27.

  18. Wang J, Gao ZY, Yan J, Ying XL, Tong SL, Yan CH. Sex differences in the effects of prenatal lead exposure on birth outcomes. Environ Pollut. 2017 Jun;225:193-200. doi: 10.1016/j.envpol.2017.03.031. Epub 2017 Apr 1.